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Entry version 101 (18 Sep 2019)
Sequence version 3 (03 Mar 2009)
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Protein

Interferon-induced protein 44-like

Gene

IFI44L

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Exhibits a low antiviral activity against hepatitis C virus.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiviral defense

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Interferon-induced protein 44-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:IFI44L
Synonyms:C1orf29
ORF Names:GS3686
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17817 IFI44L

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
613975 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q53G44

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
10964

Open Targets

More...
OpenTargetsi
ENSG00000137959

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA25615

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
IFI44L

Domain mapping of disease mutations (DMDM)

More...
DMDMi
224471886

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003378451 – 452Interferon-induced protein 44-likeAdd BLAST452

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q53G44

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q53G44

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q53G44

PeptideAtlas

More...
PeptideAtlasi
Q53G44

PRoteomics IDEntifications database

More...
PRIDEi
Q53G44

ProteomicsDB human proteome resource

More...
ProteomicsDBi
62472 [Q53G44-1]
62473 [Q53G44-2]

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q53G44

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By type I interferons.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000137959 Expressed in 209 organ(s), highest expression level in medulla oblongata

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q53G44 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q53G44 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA053247
HPA060372

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
116163, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q53G44, 1 interactor

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000359787

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 159TLDcPROSITE-ProRule annotationAdd BLAST159

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the IFI44 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IDX3 Eukaryota
ENOG410XP4J LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000163189

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000035123

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q53G44

Identification of Orthologs from Complete Genome Data

More...
OMAi
TRLTWND

Database of Orthologous Groups

More...
OrthoDBi
570957at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q53G44

TreeFam database of animal gene trees

More...
TreeFami
TF328728

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006073 GTP_binding_domain
IPR024644 IFI44_fam
IPR027417 P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR14241:SF2 PTHR14241:SF2, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01926 MMR_HSR1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51886 TLDC, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q53G44-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEVTTRLTWN DENHLRKLLG NVSLSLLYKS SVHGGSIEDM VERCSRQGCT
60 70 80 90 100
ITMAYIDYNM IVAFMLGNYI NLHESSTEPN DSLWFSLQKK NDTTEIETLL
110 120 130 140 150
LNTAPKIIDE QLVCRLSKTD IFIICRDNKI YLDKMITRNL KLRFYGHRQY
160 170 180 190 200
LECEVFRVEG IKDNLDDIKR IIKAREHRNR LLADIRDYRP YADLVSEIRI
210 220 230 240 250
LLVGPVGSGK SSFFNSVKSI FHGHVTGQAV VGSDITSITE RYRIYSVKDG
260 270 280 290 300
KNGKSLPFML CDTMGLDGAE GAGLCMDDIP HILKGCMPDR YQFNSRKPIT
310 320 330 340 350
PEHSTFITSP SLKDRIHCVA YVLDINSIDN LYSKMLAKVK QVHKEVLNCG
360 370 380 390 400
IAYVALLTKV DDCSEVLQDN FLNMSRSMTS QSRVMNVHKM LGIPISNILM
410 420 430 440 450
VGNYASDLEL DPMKDILILS ALRQMLRAAD DFLEDLPLEE TGAIERALQP

CI
Length:452
Mass (Da):51,322
Last modified:March 3, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE12E2DAF00547D7F
GO
Isoform 2 (identifier: Q53G44-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     161-161: I → M
     162-452: Missing.

Note: No experimental confirmation available.
Show »
Length:161
Mass (Da):18,825
Checksum:i9E67486F73BA8786
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7C1K6H7C1K6_HUMAN
Interferon-induced protein 44-like
IFI44L
232Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JPJ0C9JPJ0_HUMAN
Interferon-induced protein 44-like
IFI44L
97Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH15932 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA19056 differs from that shown. Reason: Frameshift at position 18.Curated
The sequence BAD96807 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti54A → V in CAD90004 (PubMed:17974005).Curated1
Sequence conflicti154E → G in CAD90004 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05464873H → R3 PublicationsCorresponds to variant dbSNP:rs273259Ensembl.1
Natural variantiVAR_054649104A → T. Corresponds to variant dbSNP:rs34932081Ensembl.1
Natural variantiVAR_054650148R → C. Corresponds to variant dbSNP:rs273258Ensembl.1
Natural variantiVAR_054651217V → I1 PublicationCorresponds to variant dbSNP:rs3820093Ensembl.1
Natural variantiVAR_054652235I → T1 PublicationCorresponds to variant dbSNP:rs987495Ensembl.1
Natural variantiVAR_054653296R → C1 PublicationCorresponds to variant dbSNP:rs1981071Ensembl.1
Natural variantiVAR_043726390M → I. Corresponds to variant dbSNP:rs35466823Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_036554161I → M in isoform 2. 1 Publication1
Alternative sequenceiVSP_036555162 – 452Missing in isoform 2. 1 PublicationAdd BLAST291

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB000115 mRNA Translation: BAA19056.1 Frameshift.
AK223087 mRNA Translation: BAD96807.1 Different initiation.
AL832618 mRNA Translation: CAD90004.1
AC104837 Genomic DNA No translation available.
BC015932 mRNA Translation: AAH15932.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS687.2 [Q53G44-1]

NCBI Reference Sequences

More...
RefSeqi
NP_006811.2, NM_006820.3 [Q53G44-1]
XP_011538841.1, XM_011540539.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000370751; ENSP00000359787; ENSG00000137959 [Q53G44-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
10964

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:10964

UCSC genome browser

More...
UCSCi
uc010oro.2 human [Q53G44-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000115 mRNA Translation: BAA19056.1 Frameshift.
AK223087 mRNA Translation: BAD96807.1 Different initiation.
AL832618 mRNA Translation: CAD90004.1
AC104837 Genomic DNA No translation available.
BC015932 mRNA Translation: AAH15932.1 Different initiation.
CCDSiCCDS687.2 [Q53G44-1]
RefSeqiNP_006811.2, NM_006820.3 [Q53G44-1]
XP_011538841.1, XM_011540539.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi116163, 2 interactors
IntActiQ53G44, 1 interactor
STRINGi9606.ENSP00000359787

PTM databases

PhosphoSitePlusiQ53G44

Polymorphism and mutation databases

BioMutaiIFI44L
DMDMi224471886

Proteomic databases

jPOSTiQ53G44
MassIVEiQ53G44
PaxDbiQ53G44
PeptideAtlasiQ53G44
PRIDEiQ53G44
ProteomicsDBi62472 [Q53G44-1]
62473 [Q53G44-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000370751; ENSP00000359787; ENSG00000137959 [Q53G44-1]
GeneIDi10964
KEGGihsa:10964
UCSCiuc010oro.2 human [Q53G44-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10964
DisGeNETi10964

GeneCards: human genes, protein and diseases

More...
GeneCardsi
IFI44L
HGNCiHGNC:17817 IFI44L
HPAiHPA053247
HPA060372
MIMi613975 gene
neXtProtiNX_Q53G44
OpenTargetsiENSG00000137959
PharmGKBiPA25615

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IDX3 Eukaryota
ENOG410XP4J LUCA
GeneTreeiENSGT00940000163189
HOGENOMiHOG000035123
InParanoidiQ53G44
OMAiTRLTWND
OrthoDBi570957at2759
PhylomeDBiQ53G44
TreeFamiTF328728

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
IFI44L human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
10964

Pharos

More...
Pharosi
Q53G44

Protein Ontology

More...
PROi
PR:Q53G44

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000137959 Expressed in 209 organ(s), highest expression level in medulla oblongata
ExpressionAtlasiQ53G44 baseline and differential
GenevisibleiQ53G44 HS

Family and domain databases

InterProiView protein in InterPro
IPR006073 GTP_binding_domain
IPR024644 IFI44_fam
IPR027417 P-loop_NTPase
PANTHERiPTHR14241:SF2 PTHR14241:SF2, 1 hit
PfamiView protein in Pfam
PF01926 MMR_HSR1, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS51886 TLDC, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiIF44L_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53G44
Secondary accession number(s): Q86TE1, Q96B64, Q99984
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: March 3, 2009
Last modified: September 18, 2019
This is version 101 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  5. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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