UniProtKB - Q53F19 (NCBP3_HUMAN)

BLAST

>sp|Q53F19|NCBP3_HUMAN Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2
MAAVRGLRVSVKAEAPAGPALGLPSPEAESGVDRGEPEPMEVEEGELEIVPVRRSLKELI
PDTSRRYENKAGSFITGIDVTSKEAIEKKEQRAKRFHFRSEVNLAQRNVALDRDMMKKAI
PKVRLETIYICGVDEMSTQDVFSYFKEYPPAHIEWLDDTSCNVVWLDEMTATRALINMSS
LPAQDKIRSRDASEDKSAEKRKKDKQEDSSDDDEAEEGEVEDENSSDVELDTLSQVEEES
LLRNDLRPANKLAKGNRLFMRFATKDDKKELGAARRSQYYMKYGNPNYGGMKGILSNSWK
RRYHSRRIQRDVIKKRALIGDDVGLTSYKHRHSGLVNVPEEPIEEEEEEEEEEEEEEEED
QDMDADDRVVVEYHEELPALKQPRERSASRRSSASSSDSDEMDYDLELKMISTPSPKKSM
KMTMYADEVESQLKNIRNSMRADSVSSSNIKNRIGNKLPPEKFADVRHLLDEKRQHSRPR
PPVSSTKSDIRQRLGKRPHSPEKAFSSNPVVRREPSSDVHSRLGVPRQDSKGLYADTREK
KSGNLWTRLGSAPKTKEKNTKKVDHRAPGAEEDDSELQRAWGALIKEKEQSRQKKSRLDN
LPSLQIEVSRESSSGSEAES

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History
Entry version 110 (07 Nov 2018)
Sequence version 2 (23 Oct 2007)
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Protein

Nuclear cap-binding protein subunit 3

Gene

NCBP3

Organism

Homo sapiens (Human)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. NCBP3 serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with NCBP3 does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the NCBP3 activity is critical to inhibit virus growth (PubMed:26382858).1 Publication

GO - Molecular functionⁱ

mRNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 26382858
RNA 7-methylguanosine cap binding
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 26382858
RNA binding
Source: UniProtKB
Inferred from high throughput direct assayⁱ
- 22658674
- 22681889

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

7-methylguanosine mRNA capping Source: UniProtKB-KW
defense response to virus
Source: UniProtKB
Inferred from mutant phenotypeⁱ
- 26382858
mRNA transport Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	RNA-binding
Biological process	Antiviral defense, mRNA capping, mRNA processing, mRNA transport, Transport

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Nuclear cap-binding protein subunit 3Imported Alternative name(s): Protein ELG
Gene namesⁱ	Name:NCBP3Imported Synonyms:C17orf85
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 17

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000074356.16
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:24612 NCBP3
MIMⁱ	616624 gene
neXtProtⁱ	NX_Q53F19

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Mutagenesisⁱ	134	D → A: Minor loss of 7-methylguanosine-containing mRNA cap binding. 1 Publication		1
Mutagenesisⁱ	155 – 158	WLDD → ALAA: Complete loss of 7-methylguanosine-containing mRNA cap binding. 1 Publication		4

Organism-specific databases

Open Targets More...OpenTargetsⁱ	ENSG00000074356
PharmGKBⁱ	PA145149545

Polymorphism and mutation databases

BioMutaⁱ	C17orf85
DMDMⁱ	160017360

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000308582	1 – 620	Nuclear cap-binding protein subunit 3Add BLAST		620

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Cross-linkⁱ	12	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	25	PhosphoserineCombined sources	1
Cross-linkⁱ	70	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	73	PhosphoserineCombined sources	1
Cross-linkⁱ	186	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	209	PhosphoserineCombined sources	1
Modified residueⁱ	210	PhosphoserineCombined sources	1
Modified residueⁱ	413	PhosphothreonineCombined sources	1
Modified residueⁱ	415	PhosphoserineCombined sources	1
Cross-linkⁱ	541	Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Modified residueⁱ	620	PhosphoserineCombined sources	1

Keywords - PTMⁱ

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDⁱ	Q53F19
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q53F19
PaxDbⁱ	Q53F19
PeptideAtlas More...PeptideAtlasⁱ	Q53F19
PRIDEⁱ	Q53F19
ProteomicsDBⁱ	62454 62455 [Q53F19-2]

PTM databases

iPTMnetⁱ	Q53F19
PhosphoSitePlusⁱ	Q53F19

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000074356 Expressed in 203 organ(s), highest expression level in testis
CleanExⁱ	HS_C17orf85
ExpressionAtlasⁱ	Q53F19 baseline and differential
Genevisibleⁱ	Q53F19 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA008959 HPA013195

HPAⁱ

HPA008959
HPA013195

Interactionⁱ

Subunit structureⁱ

Component of an alternative cap-binding complex (CBC) composed of NCBP1/CBP80 and NCBP3. Interacts with SRRT, KPNA3, THOC5 and EIF4A3.1 Publication

Protein-protein interaction databases

BioGridⁱ	120662, 60 interactors
ComplexPortalⁱ	CPX-3624 Alternative nuclear cap-binding complex
IntActⁱ	Q53F19, 31 interactors
Molecular INTeraction database More...MINTⁱ	Q53F19
STRINGⁱ	9606.ENSP00000373657

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q53F19
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	126 – 187	RNA recognition motif (RRM) domain1 PublicationAdd BLAST		62

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	155 – 158	WLDD motif; essential for 7-methylguanosine-containing mRNA cap binding1 Publication		4

Compositional bias

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Compositional biasⁱ	340 – 376	Glu-richAdd BLAST		37

Sequence similaritiesⁱ

Belongs to the NCBP3 family.Curated

Phylogenomic databases

eggNOGⁱ	ENOG410IHKG Eukaryota ENOG4110MQP LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000005712
HOGENOMⁱ	HOG000059260
HOVERGENⁱ	HBG059983
InParanoidⁱ	Q53F19
OMAⁱ	QDIFSYF
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0ELU
PhylomeDBⁱ	Q53F19
TreeFamⁱ	TF331339

Family and domain databases

Gene3Dⁱ	3.30.70.330, 1 hit
InterProⁱ	View protein in InterPro IPR019416 NCBP3 IPR012677 Nucleotide-bd_a/b_plait_sf
PANTHERⁱ	PTHR16291 PTHR16291, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF10309 NCBP3, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q53F19-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAAVRGLRVS VKAEAPAGPA LGLPSPEAES GVDRGEPEPM EVEEGELEIV 
        60         70         80         90        100
PVRRSLKELI PDTSRRYENK AGSFITGIDV TSKEAIEKKE QRAKRFHFRS 
       110        120        130        140        150
EVNLAQRNVA LDRDMMKKAI PKVRLETIYI CGVDEMSTQD VFSYFKEYPP 
       160        170        180        190        200
AHIEWLDDTS CNVVWLDEMT ATRALINMSS LPAQDKIRSR DASEDKSAEK 
       210        220        230        240        250
RKKDKQEDSS DDDEAEEGEV EDENSSDVEL DTLSQVEEES LLRNDLRPAN 
       260        270        280        290        300
KLAKGNRLFM RFATKDDKKE LGAARRSQYY MKYGNPNYGG MKGILSNSWK 
       310        320        330        340        350
RRYHSRRIQR DVIKKRALIG DDVGLTSYKH RHSGLVNVPE EPIEEEEEEE 
       360        370        380        390        400
EEEEEEEEED QDMDADDRVV VEYHEELPAL KQPRERSASR RSSASSSDSD 
       410        420        430        440        450
EMDYDLELKM ISTPSPKKSM KMTMYADEVE SQLKNIRNSM RADSVSSSNI 
       460        470        480        490        500
KNRIGNKLPP EKFADVRHLL DEKRQHSRPR PPVSSTKSDI RQRLGKRPHS 
       510        520        530        540        550
PEKAFSSNPV VRREPSSDVH SRLGVPRQDS KGLYADTREK KSGNLWTRLG 
       560        570        580        590        600
SAPKTKEKNT KKVDHRAPGA EEDDSELQRA WGALIKEKEQ SRQKKSRLDN 
       610        620
LPSLQIEVSR ESSSGSEAES

Length:620

Mass (Da):70,593

Last modified:October 23, 2007 - v2

Checksum:ⁱ78ABD2F3E0BE4760

Isoform 2 (identifier: Q53F19-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-280: Missing.

« Hide

        10         20         30         40         50
MKYGNPNYGG MKGILSNSWK RRYHSRRIQR DVIKKRALIG DDVGLTSYKH 
        60         70         80         90        100
RHSGLVNVPE EPIEEEEEEE EEEEEEEEED QDMDADDRVV VEYHEELPAL 
       110        120        130        140        150
KQPRERSASR RSSASSSDSD EMDYDLELKM ISTPSPKKSM KMTMYADEVE 
       160        170        180        190        200
SQLKNIRNSM RADSVSSSNI KNRIGNKLPP EKFADVRHLL DEKRQHSRPR 
       210        220        230        240        250
PPVSSTKSDI RQRLGKRPHS PEKAFSSNPV VRREPSSDVH SRLGVPRQDS 
       260        270        280        290        300
KGLYADTREK KSGNLWTRLG SAPKTKEKNT KKVDHRAPGA EEDDSELQRA 
       310        320        330        340
WGALIKEKEQ SRQKKSRLDN LPSLQIEVSR ESSSGSEAES

Show »

Length:340

Mass (Da):38,920

Checksum:ⁱ7C1D9D36C19FE9B2

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

K7ELP6	K7ELP6_HUMAN	Nuclear cap-binding protein subunit... Nuclear cap-binding protein subunit 3	NCBP3	80	Annotation score:
K7EQA5	K7EQA5_HUMAN	Nuclear cap-binding protein subunit... Nuclear cap-binding protein subunit 3	NCBP3	36	Annotation score:

Sequence cautionⁱ

The sequence BAD97190 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	465	D → N in BAD97190 (Ref. 5) Curated		1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_028999	1 – 280	Missing in isoform 2. 2 PublicationsAdd BLAST		280

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ277841 mRNA Translation: CAB91001.1 AC005940 Genomic DNA No translation available. AC116914 Genomic DNA No translation available. AK125048 mRNA Translation: BAG54129.1 AK223470 mRNA Translation: BAD97190.1 Different initiation. CH471108 Genomic DNA Translation: EAW90479.1 BC010707 mRNA Translation: AAH10707.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS45578.1 [Q53F19-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_001107590.1, NM_001114118.2 [Q53F19-1] XP_016880318.1, XM_017024829.1 [Q53F19-2]
UniGeneⁱ	Hs.120963

Genome annotation databases

Ensemblⁱ	ENST00000389005; ENSP00000373657; ENSG00000074356 [Q53F19-1]
GeneIDⁱ	55421
KEGGⁱ	hsa:55421
UCSC genome browser More...UCSCⁱ	uc010ckl.3 human [Q53F19-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q53F19	Nuclear cap binding subunit 3		GORGO		619	UniRef100_Q53F19
Isoform 2 of Nuclear cap-binding protein subunit 3		HUMAN		340
UPI0008F46ECA		GORGO		581
UPI0007DC7B64		HUMAN		485

Protein	Similar proteins		Species	Score	Length	Source
Q53F19	Nuclear cap-binding protein subunit 3		MOUSE		615	UniRef90_Q53F19
Nuclear cap binding subunit 3		GORGO		619
Isoform 2 of Nuclear cap-binding protein subunit 3		HUMAN		340
Uncharacterized protein C17orf85		CASCN		637
Nuclear cap binding subunit 3		SAIBB		630
+156

Protein	Similar proteins		Species	Score	Length	Source
Q53F19	Nuclear cap-binding protein subunit 3		MOUSE		615	UniRef50_Q53F19
Nuclear cap-binding protein subunit 3		CHICK		604
Nuclear cap binding subunit 3		GORGO		619
Isoform 2 of Nuclear cap-binding protein subunit 3		HUMAN		340
Uncharacterized protein C17orf85		CASCN		637
+191

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ277841 mRNA Translation: CAB91001.1 AC005940 Genomic DNA No translation available. AC116914 Genomic DNA No translation available. AK125048 mRNA Translation: BAG54129.1 AK223470 mRNA Translation: BAD97190.1 Different initiation. CH471108 Genomic DNA Translation: EAW90479.1 BC010707 mRNA Translation: AAH10707.1
CCDSⁱ	CCDS45578.1 [Q53F19-1]
RefSeqⁱ	NP_001107590.1, NM_001114118.2 [Q53F19-1] XP_016880318.1, XM_017024829.1 [Q53F19-2]
UniGeneⁱ	Hs.120963

3D structure databases

ProteinModelPortalⁱ	Q53F19
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	120662, 60 interactors
ComplexPortalⁱ	CPX-3624 Alternative nuclear cap-binding complex
IntActⁱ	Q53F19, 31 interactors
MINTⁱ	Q53F19
STRINGⁱ	9606.ENSP00000373657

PTM databases

iPTMnetⁱ	Q53F19
PhosphoSitePlusⁱ	Q53F19

Polymorphism and mutation databases

BioMutaⁱ	C17orf85
DMDMⁱ	160017360

Proteomic databases

EPDⁱ	Q53F19
MaxQBⁱ	Q53F19
PaxDbⁱ	Q53F19
PeptideAtlasⁱ	Q53F19
PRIDEⁱ	Q53F19
ProteomicsDBⁱ	62454 62455 [Q53F19-2]

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	55421
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000389005; ENSP00000373657; ENSG00000074356 [Q53F19-1]
GeneIDⁱ	55421
KEGGⁱ	hsa:55421
UCSCⁱ	uc010ckl.3 human [Q53F19-1]

Organism-specific databases

CTDⁱ	55421
EuPathDBⁱ	HostDB:ENSG00000074356.16
GeneCardsⁱ	NCBP3
H-InvDBⁱ	HIX0039403
HGNCⁱ	HGNC:24612 NCBP3
HPAⁱ	HPA008959 HPA013195
MIMⁱ	616624 gene
neXtProtⁱ	NX_Q53F19
OpenTargetsⁱ	ENSG00000074356
PharmGKBⁱ	PA145149545
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	ENOG410IHKG Eukaryota ENOG4110MQP LUCA
GeneTreeⁱ	ENSGT00390000005712
HOGENOMⁱ	HOG000059260
HOVERGENⁱ	HBG059983
InParanoidⁱ	Q53F19
OMAⁱ	QDIFSYF
OrthoDBⁱ	EOG091G0ELU
PhylomeDBⁱ	Q53F19
TreeFamⁱ	TF331339

Miscellaneous databases

ChiTaRSⁱ	NCBP3 human
GenomeRNAiⁱ	55421
Protein Ontology More...PROⁱ	PR:Q53F19
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000074356 Expressed in 203 organ(s), highest expression level in testis
CleanExⁱ	HS_C17orf85
ExpressionAtlasⁱ	Q53F19 baseline and differential
Genevisibleⁱ	Q53F19 HS

Family and domain databases

Gene3Dⁱ	3.30.70.330, 1 hit
InterProⁱ	View protein in InterPro IPR019416 NCBP3 IPR012677 Nucleotide-bd_a/b_plait_sf
PANTHERⁱ	PTHR16291 PTHR16291, 1 hit
Pfamⁱ	View protein in Pfam PF10309 NCBP3, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NCBP3_HUMAN
Accessionⁱ	Q53F19Primary (citable) accession number: Q53F19 Secondary accession number(s): B3KWG7 , Q7L406, Q96FK1, Q9NXZ4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	October 23, 2007
	Last sequence update:	October 23, 2007
	Last modified:	November 7, 2018
	This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
Human chromosome 17
Human chromosome 17: entries, gene names and cross-references to MIM

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Supporting data

UniProtKB - Q53F19 (NCBP3_HUMAN)

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Nuclear cap-binding protein subunit 3

NCBP3

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Motif

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

Experimental Info

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Sequence cautionⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ