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Protein

Elongation factor Tu-1

Gene

tuf1

Organism
Streptomyces collinus
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi19 – 26GTPUniRule annotation8
Nucleotide bindingi83 – 87GTPUniRule annotation5
Nucleotide bindingi138 – 141GTPUniRule annotation4

GO - Molecular functioni

Keywordsi

Molecular functionElongation factor
Biological processProtein biosynthesis
LigandGTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Elongation factor Tu-1UniRule annotation
Short name:
EF-Tu-1UniRule annotation
Gene namesi
Name:tuf1UniRule annotation
OrganismiStreptomyces collinus
Taxonomic identifieri42684 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000914031 – 397Elongation factor Tu-1Add BLAST397

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei386PhosphothreonineBy similarity1

Post-translational modificationi

Phosphorylated on threonine and serine.

Keywords - PTMi

Phosphoprotein

Proteomic databases

PRIDEiQ53871

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliQ53871
SMRiQ53871
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini10 – 206tr-type GAdd BLAST197

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni19 – 26G1By similarity8
Regioni62 – 66G2By similarity5
Regioni83 – 86G3By similarity4
Regioni138 – 141G4By similarity4
Regioni176 – 178G5By similarity3

Sequence similaritiesi

Family and domain databases

CDDicd03697 EFTU_II, 1 hit
HAMAPiMF_00118_B EF_Tu_B, 1 hit
InterProiView protein in InterPro
IPR004161 EFTu-like_2
IPR033720 EFTU_2
IPR031157 G_TR_CS
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR000795 TF_GTP-bd_dom
IPR009000 Transl_B-barrel_sf
IPR009001 Transl_elong_EF1A/Init_IF2_C
IPR004541 Transl_elong_EFTu/EF1A_bac/org
IPR004160 Transl_elong_EFTu/EF1A_C
PfamiView protein in Pfam
PF00009 GTP_EFTU, 1 hit
PF03144 GTP_EFTU_D2, 1 hit
PF03143 GTP_EFTU_D3, 1 hit
PRINTSiPR00315 ELONGATNFCT
SUPFAMiSSF50447 SSF50447, 1 hit
SSF50465 SSF50465, 1 hit
SSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00485 EF-Tu, 1 hit
TIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS00301 G_TR_1, 1 hit
PS51722 G_TR_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q53871-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKAKFERTK PHVNIGTIGH IDHGKTTLTA AITKVLHDAF PDLNEASAFD
60 70 80 90 100
QIDKAPEERQ RGITISIAHV EYQTETRHYA HVDCPGHADY IKNMITGAAQ
110 120 130 140 150
MDGAILVVAA TDGPMPQTKE HVLLARQVGV PYIVVALNKA DMVDDEEILE
160 170 180 190 200
LVELEVRELL SEYEFPGDDL PVVRVSALKA LEGDKEWGQS VLNLMQAVDE
210 220 230 240 250
NIPEPERDVD KPFLMPIEDV FTITGRGTVV TGRIERGVLK VNETVDIIGI
260 270 280 290 300
KTEKTTTTVT GIEMFRKLLD EGQAGENVGL LLRGIKREDV ERGQVIIKPG
310 320 330 340 350
SVTPHTEFEA QAYILSKDEG GRHTPFFNNY RPQFYFRTTD VTGVVTLPEG
360 370 380 390
TEMVMPGDNT EMKVELIQPV AMEEGLKFAI REGGRTVGAG QVTKINK
Length:397
Mass (Da):43,879
Last modified:November 1, 1997 - v1
Checksum:iD72A4054CA2EB567
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S79408 Genomic DNA Translation: AAC60496.1
PIRiPC4060

Similar proteinsi

Entry informationi

Entry nameiEFTU1_STRCU
AccessioniPrimary (citable) accession number: Q53871
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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