Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Xylanase/beta-glucanase

Gene

xynD

Organism
Ruminococcus flavefaciens
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Contains two catalytic domains with xylanase and endo-beta-1,3-1,4 glucanase activities.

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds.

Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei124NucleophileBy similarity1
Active sitei226Proton donorPROSITE-ProRule annotation1
Active sitei684NucleophileBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosidase, Hydrolase, Multifunctional enzyme
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayi
UPA00114

Protein family/group databases

CAZyiCBM22 Carbohydrate-Binding Module Family 22
GH11 Glycoside Hydrolase Family 11
GH16 Glycoside Hydrolase Family 16
mycoCLAPiZXG11D_RUMFL

Names & Taxonomyi

Protein namesi
Recommended name:
Xylanase/beta-glucanase
Including the following 2 domains:
Endo-1,4-beta-xylanase (EC:3.2.1.8)
Short name:
Xylanase
Endo-beta-1,3-1,4 glucanase (EC:3.2.1.73)
Alternative name(s):
1,3-1,4-beta-D-glucan 4-glucanohydrolase
Lichenase
Gene namesi
Name:xynD
OrganismiRuminococcus flavefaciens
Taxonomic identifieri1265 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesRuminococcaceaeRuminococcus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 31Sequence analysisAdd BLAST31
ChainiPRO_000000800932 – 802Xylanase/beta-glucanaseAdd BLAST771

Proteomic databases

PRIDEiQ53317

Structurei

3D structure databases

ProteinModelPortaliQ53317
SMRiQ53317
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini32 – 239GH11PROSITE-ProRule annotationAdd BLAST208
Domaini258 – 404CBM-cenCAdd BLAST147
Domaini434 – 513DockerinPROSITE-ProRule annotationAdd BLAST80
Domaini556 – 792GH16PROSITE-ProRule annotationAdd BLAST237

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni245 – 523BAdd BLAST279
Regioni524 – 555LinkerAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi524 – 529Poly-Thr6
Compositional biasi532 – 543Poly-ThrAdd BLAST12
Compositional biasi546 – 553Poly-Thr8

Sequence similaritiesi

In the N-terminal section; belongs to the glycosyl hydrolase 11 (cellulase G) family.Curated
In the C-terminal section; belongs to the glycosyl hydrolase 16 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di2.60.120.180, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008264 Beta_glucanase
IPR003305 CenC_carb-bd
IPR013320 ConA-like_dom_sf
IPR016134 Dockerin_dom
IPR036439 Dockerin_dom_sf
IPR008979 Galactose-bd-like_sf
IPR013319 GH11/12
IPR018208 GH11_AS_1
IPR033119 GH11_AS_2
IPR033123 GH11_dom
IPR000757 GH16
IPR008263 GH16_AS
PfamiView protein in Pfam
PF02018 CBM_4_9, 1 hit
PF00457 Glyco_hydro_11, 1 hit
PF00722 Glyco_hydro_16, 1 hit
PRINTSiPR00737 GLHYDRLASE16
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 2 hits
SSF63446 SSF63446, 1 hit
PROSITEiView protein in PROSITE
PS51766 DOCKERIN, 1 hit
PS00776 GH11_1, 1 hit
PS00777 GH11_2, 1 hit
PS51761 GH11_3, 1 hit
PS01034 GH16_1, 1 hit
PS51762 GH16_2, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q53317-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKSIFKRYA AAVGLMASVL MFTAVPTTSN AADDQKTGKV GGFDWEMWNQ
60 70 80 90 100
NYTGTVSMNP GAGSFTCSWS GIENFLARMG KNYDDQKKNY KAFGDIVLTY
110 120 130 140 150
DVEYTPRGNS YMCIYGWTRN PLMEYYIVEG WGDWEPPGND GVDNFGTTTI
160 170 180 190 200
DGKTYKIRKS MRYNQPSIEG TKTFPQYWSV RTTSGSRNNT TNYMKDQVSV
210 220 230 240 250
TKHFDAWSKA GLDMSGTLYE VSLNIEGYRS NGSANVKSIS FDGGIDIPDP
260 270 280 290 300
EPIKPDENGY YLKENFESGE GNWSGRGSAK VKSSSGYDGT KGIFVSGRED
310 320 330 340 350
TWNGASINLD ELTFKAGETY SLGTAVMQDF ESSVDFKLTL QYTDADGKEN
360 370 380 390 400
YDEVKTVTAA KGQWVDLSNS SYTIPSGATG LVLYVEVPES KTDFYMDGAY
410 420 430 440 450
AGVKGTKPLI SISSQSVDPP VTEPTNPTNP TGPSVTKWGD ANCDGGVDLS
460 470 480 490 500
DAIFIMQFLA NPNKYGLTGT ETNHMTNQGK VNGDVCEHGS GLTEDDAVSI
510 520 530 540 550
QKYLIRAISE LPESYLEGHD PSKTTTTTTR ITTTTTTTTT TTTSKTTTTT
560 570 580 590 600
TTTSPAMHGG YRDLGTPMNT SATMISDFRT GKAGDFFASD GWTNGKPFDC
610 620 630 640 650
WWYKRNAVIN DGCLQLSIDQ KWTNDKNPDW DPRYSGGEFR TNNFYHYGYY
660 670 680 690 700
ECSMQAMKND GVVSSFFTYT GPSDDNPWDE IDIEILGKNT TQVQFNYYTN
710 720 730 740 750
GQGKHEKLYD LGFDSSEAYH TYGFDWQPNY IAWYVDGREV YRATQDIPKT
760 770 780 790 800
PGKIMMNAWP GLTVDDWLKA FNGRTPLTAH YQWVTYNKNG VQHSSQGQNP

WG
Length:802
Mass (Da):89,091
Last modified:November 1, 1997 - v2
Checksum:i2880A689647284AF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S61204 Genomic DNA Translation: AAB26620.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S61204 Genomic DNA Translation: AAB26620.1

3D structure databases

ProteinModelPortaliQ53317
SMRiQ53317
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiCBM22 Carbohydrate-Binding Module Family 22
GH11 Glycoside Hydrolase Family 11
GH16 Glycoside Hydrolase Family 16
mycoCLAPiZXG11D_RUMFL

Proteomic databases

PRIDEiQ53317

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00114

Family and domain databases

Gene3Di2.60.120.180, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008264 Beta_glucanase
IPR003305 CenC_carb-bd
IPR013320 ConA-like_dom_sf
IPR016134 Dockerin_dom
IPR036439 Dockerin_dom_sf
IPR008979 Galactose-bd-like_sf
IPR013319 GH11/12
IPR018208 GH11_AS_1
IPR033119 GH11_AS_2
IPR033123 GH11_dom
IPR000757 GH16
IPR008263 GH16_AS
PfamiView protein in Pfam
PF02018 CBM_4_9, 1 hit
PF00457 Glyco_hydro_11, 1 hit
PF00722 Glyco_hydro_16, 1 hit
PRINTSiPR00737 GLHYDRLASE16
SUPFAMiSSF49785 SSF49785, 1 hit
SSF49899 SSF49899, 2 hits
SSF63446 SSF63446, 1 hit
PROSITEiView protein in PROSITE
PS51766 DOCKERIN, 1 hit
PS00776 GH11_1, 1 hit
PS00777 GH11_2, 1 hit
PS51761 GH11_3, 1 hit
PS01034 GH16_1, 1 hit
PS51762 GH16_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiXYND_RUMFL
AccessioniPrimary (citable) accession number: Q53317
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 22, 2017
This is version 93 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again