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UniProtKB - Q53317 (XYND_RUMFL)

Entry version 97 (17 Jun 2020)
Sequence version 2 (01 Nov 1997)
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Protein

Xylanase/beta-glucanase

Gene

xynD

Organism
Ruminococcus flavefaciens
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Contains two catalytic domains with xylanase and endo-beta-1,3-1,4 glucanase activities.

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8
  • Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds. EC:3.2.1.73

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: xylan degradation

This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.
View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei124NucleophileBy similarity1
Active sitei226Proton donorPROSITE-ProRule annotation1
Active sitei684NucleophileBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosidase, Hydrolase, Multifunctional enzyme
Biological processCarbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...UniPathwayi		UPA00114

Protein family/group databases

Carbohydrate-Active enZymes

More...CAZyi		CBM22, Carbohydrate-Binding Module Family 22
GH11, Glycoside Hydrolase Family 11
GH16, Glycoside Hydrolase Family 16

CLAE, a database of fungal genes encoding lignocellulose-active proteins

More...CLAEi		ZXG11D_RUMFL

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Xylanase/beta-glucanase
Including the following 2 domains:
Endo-1,4-beta-xylanase (EC:3.2.1.8)
Short name:
Xylanase
Endo-beta-1,3-1,4 glucanase (EC:3.2.1.73)
Alternative name(s):
1,3-1,4-beta-D-glucan 4-glucanohydrolase
Lichenase
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:xynD
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRuminococcus flavefaciens
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1265 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteria › Firmicutes › Clostridia › Clostridiales › Ruminococcaceae › Ruminococcus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 31Sequence analysisAdd BLAST31
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000000800932 – 802Xylanase/beta-glucanaseAdd BLAST771

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		Q53317

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q53317

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini32 – 239GH11PROSITE-ProRule annotationAdd BLAST208
Domaini258 – 404CBM-cenCAdd BLAST147
Domaini434 – 513DockerinPROSITE-ProRule annotationAdd BLAST80
Domaini556 – 792GH16PROSITE-ProRule annotationAdd BLAST237

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni245 – 523BAdd BLAST279
Regioni524 – 555LinkerAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi524 – 529Poly-Thr6
Compositional biasi532 – 543Poly-ThrAdd BLAST12
Compositional biasi546 – 553Poly-Thr8

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

In the N-terminal section; belongs to the glycosyl hydrolase 11 (cellulase G) family.Curated
In the C-terminal section; belongs to the glycosyl hydrolase 16 family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1330.10, 1 hit
2.60.120.180, 1 hit
2.60.120.260, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR008264, Beta_glucanase
IPR003305, CenC_carb-bd
IPR013320, ConA-like_dom_sf
IPR016134, Dockerin_dom
IPR036439, Dockerin_dom_sf
IPR008979, Galactose-bd-like_sf
IPR013319, GH11/12
IPR018208, GH11_AS_1
IPR033119, GH11_AS_2
IPR033123, GH11_dom
IPR000757, GH16
IPR008263, GH16_AS

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02018, CBM_4_9, 1 hit
PF00457, Glyco_hydro_11, 1 hit
PF00722, Glyco_hydro_16, 1 hit

Protein Motif fingerprint database; a protein domain database

More...PRINTSi		PR00737, GLHYDRLASE16

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF49785, SSF49785, 1 hit
SSF49899, SSF49899, 2 hits
SSF63446, SSF63446, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51766, DOCKERIN, 1 hit
PS00776, GH11_1, 1 hit
PS00777, GH11_2, 1 hit
PS51761, GH11_3, 1 hit
PS01034, GH16_1, 1 hit
PS51762, GH16_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

Q53317-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKKSIFKRYA AAVGLMASVL MFTAVPTTSN AADDQKTGKV GGFDWEMWNQ 
        60         70         80         90        100
NYTGTVSMNP GAGSFTCSWS GIENFLARMG KNYDDQKKNY KAFGDIVLTY 
       110        120        130        140        150
DVEYTPRGNS YMCIYGWTRN PLMEYYIVEG WGDWEPPGND GVDNFGTTTI 
       160        170        180        190        200
DGKTYKIRKS MRYNQPSIEG TKTFPQYWSV RTTSGSRNNT TNYMKDQVSV 
       210        220        230        240        250
TKHFDAWSKA GLDMSGTLYE VSLNIEGYRS NGSANVKSIS FDGGIDIPDP 
       260        270        280        290        300
EPIKPDENGY YLKENFESGE GNWSGRGSAK VKSSSGYDGT KGIFVSGRED 
       310        320        330        340        350
TWNGASINLD ELTFKAGETY SLGTAVMQDF ESSVDFKLTL QYTDADGKEN 
       360        370        380        390        400
YDEVKTVTAA KGQWVDLSNS SYTIPSGATG LVLYVEVPES KTDFYMDGAY 
       410        420        430        440        450
AGVKGTKPLI SISSQSVDPP VTEPTNPTNP TGPSVTKWGD ANCDGGVDLS 
       460        470        480        490        500
DAIFIMQFLA NPNKYGLTGT ETNHMTNQGK VNGDVCEHGS GLTEDDAVSI 
       510        520        530        540        550
QKYLIRAISE LPESYLEGHD PSKTTTTTTR ITTTTTTTTT TTTSKTTTTT 
       560        570        580        590        600
TTTSPAMHGG YRDLGTPMNT SATMISDFRT GKAGDFFASD GWTNGKPFDC 
       610        620        630        640        650
WWYKRNAVIN DGCLQLSIDQ KWTNDKNPDW DPRYSGGEFR TNNFYHYGYY 
       660        670        680        690        700
ECSMQAMKND GVVSSFFTYT GPSDDNPWDE IDIEILGKNT TQVQFNYYTN 
       710        720        730        740        750
GQGKHEKLYD LGFDSSEAYH TYGFDWQPNY IAWYVDGREV YRATQDIPKT 
       760        770        780        790        800
PGKIMMNAWP GLTVDDWLKA FNGRTPLTAH YQWVTYNKNG VQHSSQGQNP 

WG
Length:802
Mass (Da):89,091
Last modified:November 1, 1997 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2880A689647284AF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
S61204 Genomic DNA Translation: AAB26620.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S61204 Genomic DNA Translation: AAB26620.1

3D structure databases

SMRiQ53317
ModBaseiSearch...

Protein family/group databases

CAZyiCBM22, Carbohydrate-Binding Module Family 22
GH11, Glycoside Hydrolase Family 11
GH16, Glycoside Hydrolase Family 16
CLAEiZXG11D_RUMFL

Proteomic databases

PRIDEiQ53317

Enzyme and pathway databases

UniPathwayiUPA00114

Family and domain databases

Gene3Di1.10.1330.10, 1 hit
2.60.120.180, 1 hit
2.60.120.260, 1 hit
InterProiView protein in InterPro
IPR008264, Beta_glucanase
IPR003305, CenC_carb-bd
IPR013320, ConA-like_dom_sf
IPR016134, Dockerin_dom
IPR036439, Dockerin_dom_sf
IPR008979, Galactose-bd-like_sf
IPR013319, GH11/12
IPR018208, GH11_AS_1
IPR033119, GH11_AS_2
IPR033123, GH11_dom
IPR000757, GH16
IPR008263, GH16_AS
PfamiView protein in Pfam
PF02018, CBM_4_9, 1 hit
PF00457, Glyco_hydro_11, 1 hit
PF00722, Glyco_hydro_16, 1 hit
PRINTSiPR00737, GLHYDRLASE16
SUPFAMiSSF49785, SSF49785, 1 hit
SSF49899, SSF49899, 2 hits
SSF63446, SSF63446, 1 hit
PROSITEiView protein in PROSITE
PS51766, DOCKERIN, 1 hit
PS00776, GH11_1, 1 hit
PS00777, GH11_2, 1 hit
PS51761, GH11_3, 1 hit
PS01034, GH16_1, 1 hit
PS51762, GH16_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiXYND_RUMFL
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q53317
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: June 17, 2020
This is version 97 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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