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UniProtKB - Q53317 (XYND_RUMFL)
Protein
Xylanase/beta-glucanase
Gene
xynD
Organism
Ruminococcus flavefaciens
Status
Functioni
Contains two catalytic domains with xylanase and endo-beta-1,3-1,4 glucanase activities.
Catalytic activityi
- Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans. EC:3.2.1.8
- Hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3)- and (1->4)-bonds. EC:3.2.1.73
: xylan degradation Pathwayi
This protein is involved in the pathway xylan degradation, which is part of Glycan degradation.View all proteins of this organism that are known to be involved in the pathway xylan degradation and in Glycan degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 124 | NucleophileBy similarity | 1 | |
Active sitei | 226 | Proton donorPROSITE-ProRule annotation | 1 | |
Active sitei | 684 | NucleophileBy similarity | 1 |
GO - Molecular functioni
- endo-1,4-beta-xylanase activity Source: UniProtKB-EC
- licheninase activity Source: UniProtKB-EC
GO - Biological processi
- xylan catabolic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | Glycosidase, Hydrolase, Multifunctional enzyme |
Biological process | Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation |
Enzyme and pathway databases
UniPathwayi | UPA00114 |
Protein family/group databases
CAZyi | CBM22, Carbohydrate-Binding Module Family 22 GH11, Glycoside Hydrolase Family 11 GH16, Glycoside Hydrolase Family 16 |
CLAEi | ZXG11D_RUMFL |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:xynD |
Organismi | Ruminococcus flavefaciens |
Taxonomic identifieri | 1265 [NCBI] |
Taxonomic lineagei | Bacteria › Firmicutes › Clostridia › Eubacteriales › Oscillospiraceae › Ruminococcus |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 31 | Sequence analysisAdd BLAST | 31 | |
ChainiPRO_0000008009 | 32 – 802 | Xylanase/beta-glucanaseAdd BLAST | 771 |
Proteomic databases
PRIDEi | Q53317 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 32 – 239 | GH11PROSITE-ProRule annotationAdd BLAST | 208 | |
Domaini | 258 – 404 | CBM-cenCAdd BLAST | 147 | |
Domaini | 434 – 513 | DockerinPROSITE-ProRule annotationAdd BLAST | 80 | |
Domaini | 556 – 792 | GH16PROSITE-ProRule annotationAdd BLAST | 237 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 245 – 523 | BAdd BLAST | 279 | |
Regioni | 414 – 436 | DisorderedSequence analysisAdd BLAST | 23 | |
Regioni | 524 – 555 | LinkerAdd BLAST | 32 | |
Regioni | 533 – 564 | DisorderedSequence analysisAdd BLAST | 32 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 533 – 557 | Polar residuesSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
In the N-terminal section; belongs to the glycosyl hydrolase 11 (cellulase G) family.Curated
In the C-terminal section; belongs to the glycosyl hydrolase 16 family.Curated
Keywords - Domaini
SignalFamily and domain databases
Gene3Di | 1.10.1330.10, 1 hit 2.60.120.180, 1 hit |
InterProi | View protein in InterPro IPR008264, Beta_glucanase IPR003305, CenC_carb-bd IPR013320, ConA-like_dom_sf IPR016134, Dockerin_dom IPR036439, Dockerin_dom_sf IPR008979, Galactose-bd-like_sf IPR013319, GH11/12 IPR018208, GH11_AS_1 IPR033119, GH11_AS_2 IPR033123, GH11_dom IPR000757, GH16 IPR008263, GH16_AS |
Pfami | View protein in Pfam PF02018, CBM_4_9, 1 hit PF00457, Glyco_hydro_11, 1 hit PF00722, Glyco_hydro_16, 1 hit |
PRINTSi | PR00737, GLHYDRLASE16 |
SUPFAMi | SSF49785, SSF49785, 1 hit SSF49899, SSF49899, 2 hits SSF63446, SSF63446, 1 hit |
PROSITEi | View protein in PROSITE PS51766, DOCKERIN, 1 hit PS00776, GH11_1, 1 hit PS00777, GH11_2, 1 hit PS51761, GH11_3, 1 hit PS01034, GH16_1, 1 hit PS51762, GH16_2, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
Q53317-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKSIFKRYA AAVGLMASVL MFTAVPTTSN AADDQKTGKV GGFDWEMWNQ
60 70 80 90 100
NYTGTVSMNP GAGSFTCSWS GIENFLARMG KNYDDQKKNY KAFGDIVLTY
110 120 130 140 150
DVEYTPRGNS YMCIYGWTRN PLMEYYIVEG WGDWEPPGND GVDNFGTTTI
160 170 180 190 200
DGKTYKIRKS MRYNQPSIEG TKTFPQYWSV RTTSGSRNNT TNYMKDQVSV
210 220 230 240 250
TKHFDAWSKA GLDMSGTLYE VSLNIEGYRS NGSANVKSIS FDGGIDIPDP
260 270 280 290 300
EPIKPDENGY YLKENFESGE GNWSGRGSAK VKSSSGYDGT KGIFVSGRED
310 320 330 340 350
TWNGASINLD ELTFKAGETY SLGTAVMQDF ESSVDFKLTL QYTDADGKEN
360 370 380 390 400
YDEVKTVTAA KGQWVDLSNS SYTIPSGATG LVLYVEVPES KTDFYMDGAY
410 420 430 440 450
AGVKGTKPLI SISSQSVDPP VTEPTNPTNP TGPSVTKWGD ANCDGGVDLS
460 470 480 490 500
DAIFIMQFLA NPNKYGLTGT ETNHMTNQGK VNGDVCEHGS GLTEDDAVSI
510 520 530 540 550
QKYLIRAISE LPESYLEGHD PSKTTTTTTR ITTTTTTTTT TTTSKTTTTT
560 570 580 590 600
TTTSPAMHGG YRDLGTPMNT SATMISDFRT GKAGDFFASD GWTNGKPFDC
610 620 630 640 650
WWYKRNAVIN DGCLQLSIDQ KWTNDKNPDW DPRYSGGEFR TNNFYHYGYY
660 670 680 690 700
ECSMQAMKND GVVSSFFTYT GPSDDNPWDE IDIEILGKNT TQVQFNYYTN
710 720 730 740 750
GQGKHEKLYD LGFDSSEAYH TYGFDWQPNY IAWYVDGREV YRATQDIPKT
760 770 780 790 800
PGKIMMNAWP GLTVDDWLKA FNGRTPLTAH YQWVTYNKNG VQHSSQGQNP
WG
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | S61204 Genomic DNA Translation: AAB26620.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | S61204 Genomic DNA Translation: AAB26620.1 |
3D structure databases
SMRi | Q53317 |
ModBasei | Search... |
Protein family/group databases
CAZyi | CBM22, Carbohydrate-Binding Module Family 22 GH11, Glycoside Hydrolase Family 11 GH16, Glycoside Hydrolase Family 16 |
CLAEi | ZXG11D_RUMFL |
Proteomic databases
PRIDEi | Q53317 |
Enzyme and pathway databases
UniPathwayi | UPA00114 |
Family and domain databases
Gene3Di | 1.10.1330.10, 1 hit 2.60.120.180, 1 hit |
InterProi | View protein in InterPro IPR008264, Beta_glucanase IPR003305, CenC_carb-bd IPR013320, ConA-like_dom_sf IPR016134, Dockerin_dom IPR036439, Dockerin_dom_sf IPR008979, Galactose-bd-like_sf IPR013319, GH11/12 IPR018208, GH11_AS_1 IPR033119, GH11_AS_2 IPR033123, GH11_dom IPR000757, GH16 IPR008263, GH16_AS |
Pfami | View protein in Pfam PF02018, CBM_4_9, 1 hit PF00457, Glyco_hydro_11, 1 hit PF00722, Glyco_hydro_16, 1 hit |
PRINTSi | PR00737, GLHYDRLASE16 |
SUPFAMi | SSF49785, SSF49785, 1 hit SSF49899, SSF49899, 2 hits SSF63446, SSF63446, 1 hit |
PROSITEi | View protein in PROSITE PS51766, DOCKERIN, 1 hit PS00776, GH11_1, 1 hit PS00777, GH11_2, 1 hit PS51761, GH11_3, 1 hit PS01034, GH16_1, 1 hit PS51762, GH16_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | XYND_RUMFL | |
Accessioni | Q53317Primary (citable) accession number: Q53317 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | November 1, 1997 | |
Last modified: | September 29, 2021 | |
This is version 99 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Documents
- PATHWAY comments
Index of metabolic and biosynthesis pathways - SIMILARITY comments
Index of protein domains and families