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Protein

Protein S-acyltransferase 24

Gene

PAT24

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Palmitoyltransferase involved in cell growth regulation.1 Publication

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei401S-palmitoyl cysteine intermediateBy similarity1

GO - Molecular functioni

  • acyl binding Source: TAIR
  • protein-cysteine S-palmitoyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  • cell tip growth Source: TAIR

Keywordsi

Molecular functionAcyltransferase, Transferase

Enzyme and pathway databases

BRENDAi2.3.1.225 399

Names & Taxonomyi

Protein namesi
Recommended name:
Protein S-acyltransferase 24 (EC:2.3.1.225)
Alternative name(s):
Ankyrin repeat-containing S-palmitoyltransferase
Palmitoyltransferase TIP1
Protein TIP GROWTH DEFECTIVE 1
Short name:
AtTIP1
Zinc finger DHHC domain-containing protein TIP1
Gene namesi
Name:PAT24
Synonyms:TIP1
Ordered Locus Names:At5g20350
ORF Names:F5O24.240
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 5

Organism-specific databases

AraportiAT5G20350
TAIRilocus:2149309 AT5G20350

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei277 – 297HelicalSequence analysisAdd BLAST21
Transmembranei308 – 328HelicalSequence analysisAdd BLAST21
Transmembranei416 – 436HelicalSequence analysisAdd BLAST21
Transmembranei462 – 482HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasmic vesicle, Golgi apparatus, Membrane

Pathology & Biotechi

Disruption phenotypei

Plants have defects in root hair growth and pollen tube germination.3 Publications

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002129151 – 620Protein S-acyltransferase 24Add BLAST620

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiQ52T38

PTM databases

iPTMnetiQ52T38
SwissPalmiQ52T38

Expressioni

Tissue specificityi

Expressed in root, leaf, inflorescence stem, pollen and floral tissue.2 Publications

Gene expression databases

ExpressionAtlasiQ52T38 baseline and differential
GenevisibleiQ52T38 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT5G20350.1

Structurei

3D structure databases

ProteinModelPortaliQ52T38
SMRiQ52T38
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati64 – 93ANK 1Add BLAST30
Repeati97 – 126ANK 2Add BLAST30
Repeati164 – 193ANK 3Add BLAST30
Repeati197 – 226ANK 4Add BLAST30
Repeati232 – 261ANK 5Add BLAST30
Domaini371 – 421DHHCPROSITE-ProRule annotationAdd BLAST51

Domaini

The DHHC domain is required for palmitoyltransferase activity.

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.Curated

Keywords - Domaini

ANK repeat, Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0509 Eukaryota
COG0666 LUCA
COG5273 LUCA
HOGENOMiHOG000243854
InParanoidiQ52T38
KOiK20032
OMAiHLNFLFI
OrthoDBiEOG093605DC
PhylomeDBiQ52T38

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF12796 Ank_2, 2 hits
PF01529 DHHC, 1 hit
SMARTiView protein in SMART
SM00248 ANK, 7 hits
SUPFAMiSSF48403 SSF48403, 1 hit
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 4 hits
PS50216 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

Q52T38-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSEIEVVEE IQSNPKENGE SSSKGIEEES LKNDVYTAAA YGDLEKLHRL
60 70 80 90 100
VECEGSSVSE PDALGYYALQ WSALNNRVAV AQYLIEHGGD VNATDHTGQT
110 120 130 140 150
ALHWSAVRGA IQVAELLLQE GARVDATDMY GYQATHVAAQ YGQTAFLCHV
160 170 180 190 200
VSKWNADPDV PDNDGRSPLH WAAYKGFADS IRLLLFLDAY RGRQDKEGCT
210 220 230 240 250
PLHWAAIRGN LEACTVLVQA GKKEDLMITD KTGLTPAQLA AEKNHRQVSF
260 270 280 290 300
FLGNARSLLE KRCDGSSPLG RLSKLGLAPV LWIMILLLLL VYTNSVVLAS
310 320 330 340 350
NLPKLTTGIG ALAWLGFILA TAGLFLFYRC SRKDPGYIRM NIHDPQTMKD
360 370 380 390 400
DEPLLKIELN NPALLAGNWT QLCATCKIIR PLRAKHCSTC DRCVEQFDHH
410 420 430 440 450
CPWVSNCVGK KNKWEFFLFL LLEVLAMLIT GGVTLARVLS DPSAPSSFGA
460 470 480 490 500
WMSHVASNHV GALSFLLVEF CLFFSVAVLT VIQASQISRN ITTNEMANAL
510 520 530 540 550
RYSYLRGPGG RFRNPYDLGC RRNCSDFLVK GYNEDIECHE EDATQRPEGI
560 570 580 590 600
SMMQMQRNPN LQNGNGHVAI DVNPTHNSQS AHVHSANCSH SHNSKSKSDN
610 620
VPLGLGLGLS RNPTRPVVSP
Length:620
Mass (Da):68,234
Last modified:May 24, 2005 - v1
Checksum:iBF6247CB99911659
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY965346 mRNA Translation: AAX89384.1
AF296825 Genomic DNA No translation available.
CP002688 Genomic DNA Translation: AED92834.1
AK228596 mRNA Translation: BAF00511.1
RefSeqiNP_197535.2, NM_122042.4
UniGeneiAt.22462

Genome annotation databases

EnsemblPlantsiAT5G20350.1; AT5G20350.1; AT5G20350
GeneIDi832157
GrameneiAT5G20350.1; AT5G20350.1; AT5G20350
KEGGiath:AT5G20350

Similar proteinsi

Entry informationi

Entry nameiZDH22_ARATH
AccessioniPrimary (citable) accession number: Q52T38
Secondary accession number(s): Q0WQT8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: May 24, 2005
Last modified: April 25, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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