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Entry version 124 (29 Sep 2021)
Sequence version 2 (13 Jun 2006)
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Protein

Enhancer of polycomb homolog 2

Gene

EPC2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in transcription or DNA repair.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulator
Biological processDNA damage, DNA repair, Transcription, Transcription regulation

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q52LR7

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Enhancer of polycomb homolog 2
Alternative name(s):
EPC-like
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:EPC2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:24543, EPC2

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
611000, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q52LR7

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSG00000135999

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
26122

Open Targets

More...
OpenTargetsi
ENSG00000135999

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA134875170

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q52LR7, Tbio

Genetic variation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
EPC2

Domain mapping of disease mutations (DMDM)

More...
DMDMi
108935980

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002392951 – 807Enhancer of polycomb homolog 2Add BLAST807

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki135Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki195Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki324Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
Cross-linki362Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei538PhosphoserineCombined sources1
Modified residuei754PhosphoserineCombined sources1

Keywords - PTMi

Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q52LR7

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q52LR7

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q52LR7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q52LR7

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q52LR7

PeptideAtlas

More...
PeptideAtlasi
Q52LR7

PRoteomics IDEntifications database

More...
PRIDEi
Q52LR7

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62425

PTM databases

CarbonylDB database of protein carbonylation sites

More...
CarbonylDBi
Q52LR7

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q52LR7, 3 sites, 1 O-linked glycan (3 sites)

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q52LR7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q52LR7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000135999, Expressed in corpus callosum and 217 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q52LR7, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q52LR7, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000135999, Low tissue specificity

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
117564, 38 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-978, NuA4 histone acetyltransferase complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q52LR7

Protein interaction database and analysis system

More...
IntActi
Q52LR7, 27 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000258484

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q52LR7, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q52LR7

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni376 – 396DisorderedSequence analysisAdd BLAST21
Regioni600 – 628DisorderedSequence analysisAdd BLAST29
Regioni645 – 673DisorderedSequence analysisAdd BLAST29

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi652 – 673Polar residuesSequence analysisAdd BLAST22

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the enhancer of polycomb family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2261, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000158526

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_012781_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q52LR7

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNEECTS

Database of Orthologous Groups

More...
OrthoDBi
957492at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q52LR7

TreeFam database of animal gene trees

More...
TreeFami
TF106438

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR024943, Enhancer_polycomb
IPR019542, Enhancer_polycomb-like_N
IPR009607, Enhancer_polycomb_C

The PANTHER Classification System

More...
PANTHERi
PTHR14898, PTHR14898, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06752, E_Pc_C, 1 hit
PF10513, EPL1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q52LR7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKLSFRARA LDAAKPLPIY RGKDMPDLND CVSINRAVPQ MPTGMEKEEE
60 70 80 90 100
SEHHLQRAIS AQQVFREKKE SMVIPVPEAE SNVNYYNRLY KGEFKQPKQF
110 120 130 140 150
IHIQPFNLDN EQPDYDMDSE DETLLNRLNR KMEIKPLQFE IMIDRLEKAS
160 170 180 190 200
SNQLVTLQEA KLLLNEDDYL IKAVYDYWVR KRKNCRGPSL IPQIKQEKRD
210 220 230 240 250
GSTNNDPYVA FRRRTEKMQT RKNRKNDEAS YEKMLKLRRE FSRAITILEM
260 270 280 290 300
IKRREKTKRE LLHLTLEVVE KRYHLGDYGG EILNEVKISR SEKELYATPA
310 320 330 340 350
TLHNGNHHKV QECKTKHPHH LSLKEEASDV VRQKKKYPKK PKAEALITSQ
360 370 380 390 400
QPTPETLPVI NKSDIKQYDF HSSDEDEFPQ VLSPVSEPEE ENDPDGPCAF
410 420 430 440 450
RRRAGCQYYA PRLDQANHSC ENSELADLDK LRYRHCLTTL TVPRRCIGFA
460 470 480 490 500
RRRIGRGGRV IMDRISTEHD PVLKQIDPEM LNSFSSSSQT IDFSSNFSRT
510 520 530 540 550
NASSKHCENR LSLSEILSNI RSCRLQCFQP RLLNLQDSDS EECTSRKPGQ
560 570 580 590 600
TVNNKRVSAA SVALLNTSKN GISVTGGITE EQFQTHQQQL VQMQRQQLAQ
610 620 630 640 650
LQQKQQSQHS SQQTHPKAQG SSTSDCMSKT LDSASAHFAA SAVVSAPVPS
660 670 680 690 700
RSEVAKEQNT GHNNINGVVQ PSGTSKTLYS TNMALSSSPG ISAVQLVRTV
710 720 730 740 750
GHTTTNHLIP ALCTSSPQTL PMNNSCLTNA VHLNNVSVVS PVNVHINTRT
760 770 780 790 800
SAPSPTALKL ATVAASMDRV PKVTPSSAIS SIARENHEPE RLGLNGIAET

TVAMEVT
Length:807
Mass (Da):91,095
Last modified:June 13, 2006 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i855433050972CA7C
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C9J1X4C9J1X4_HUMAN
Enhancer of polycomb homolog
EPC2
160Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E7ETK1E7ETK1_HUMAN
Enhancer of polycomb homolog
EPC2
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PBA8E9PBA8_HUMAN
Enhancer of polycomb homolog 2
EPC2
121Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H7C0K5H7C0K5_HUMAN
Enhancer of polycomb homolog 2
EPC2
126Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH93818 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH93820 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAK60500 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA91688 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAA92032 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti723N → D in CAB55993 (PubMed:17974005).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF286904 mRNA Translation: AAK60500.1 Different initiation.
AK002010 mRNA Translation: BAA92032.1 Different initiation.
AK001433 mRNA Translation: BAA91688.1 Different initiation.
AK125789 mRNA Translation: BAG54249.1
CH471058 Genomic DNA Translation: EAX11547.1
CH471058 Genomic DNA Translation: EAX11548.1
BC093818 mRNA Translation: AAH93818.1 Different initiation.
BC093820 mRNA Translation: AAH93820.1 Different initiation.
AL117558 mRNA Translation: CAB55993.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46422.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T17303

NCBI Reference Sequences

More...
RefSeqi
NP_056445.3, NM_015630.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000258484; ENSP00000258484; ENSG00000135999

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
26122

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:26122

UCSC genome browser

More...
UCSCi
uc010zbt.3, human

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF286904 mRNA Translation: AAK60500.1 Different initiation.
AK002010 mRNA Translation: BAA92032.1 Different initiation.
AK001433 mRNA Translation: BAA91688.1 Different initiation.
AK125789 mRNA Translation: BAG54249.1
CH471058 Genomic DNA Translation: EAX11547.1
CH471058 Genomic DNA Translation: EAX11548.1
BC093818 mRNA Translation: AAH93818.1 Different initiation.
BC093820 mRNA Translation: AAH93820.1 Different initiation.
AL117558 mRNA Translation: CAB55993.1
CCDSiCCDS46422.1
PIRiT17303
RefSeqiNP_056445.3, NM_015630.3

3D structure databases

SMRiQ52LR7
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi117564, 38 interactors
ComplexPortaliCPX-978, NuA4 histone acetyltransferase complex
CORUMiQ52LR7
IntActiQ52LR7, 27 interactors
STRINGi9606.ENSP00000258484

PTM databases

CarbonylDBiQ52LR7
GlyGeniQ52LR7, 3 sites, 1 O-linked glycan (3 sites)
iPTMnetiQ52LR7
PhosphoSitePlusiQ52LR7

Genetic variation databases

BioMutaiEPC2
DMDMi108935980

Proteomic databases

EPDiQ52LR7
jPOSTiQ52LR7
MassIVEiQ52LR7
MaxQBiQ52LR7
PaxDbiQ52LR7
PeptideAtlasiQ52LR7
PRIDEiQ52LR7
ProteomicsDBi62425

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
51789, 58 antibodies

The DNASU plasmid repository

More...
DNASUi
26122

Genome annotation databases

EnsembliENST00000258484; ENSP00000258484; ENSG00000135999
GeneIDi26122
KEGGihsa:26122
UCSCiuc010zbt.3, human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
26122
DisGeNETi26122

GeneCards: human genes, protein and diseases

More...
GeneCardsi
EPC2
HGNCiHGNC:24543, EPC2
HPAiENSG00000135999, Low tissue specificity
MIMi611000, gene
neXtProtiNX_Q52LR7
OpenTargetsiENSG00000135999
PharmGKBiPA134875170
VEuPathDBiHostDB:ENSG00000135999

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG2261, Eukaryota
GeneTreeiENSGT00940000158526
HOGENOMiCLU_012781_0_0_1
InParanoidiQ52LR7
OMAiDNEECTS
OrthoDBi957492at2759
PhylomeDBiQ52LR7
TreeFamiTF106438

Enzyme and pathway databases

PathwayCommonsiQ52LR7

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
26122, 195 hits in 1024 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
EPC2, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
26122
PharosiQ52LR7, Tbio

Protein Ontology

More...
PROi
PR:Q52LR7
RNActiQ52LR7, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000135999, Expressed in corpus callosum and 217 other tissues
ExpressionAtlasiQ52LR7, baseline and differential
GenevisibleiQ52LR7, HS

Family and domain databases

InterProiView protein in InterPro
IPR024943, Enhancer_polycomb
IPR019542, Enhancer_polycomb-like_N
IPR009607, Enhancer_polycomb_C
PANTHERiPTHR14898, PTHR14898, 1 hit
PfamiView protein in Pfam
PF06752, E_Pc_C, 1 hit
PF10513, EPL1, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEPC2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q52LR7
Secondary accession number(s): B3KWT7
, D3DP89, Q7L9J1, Q96RR7, Q9NUT8, Q9NVR1, Q9UFM9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: June 13, 2006
Last modified: September 29, 2021
This is version 124 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families
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