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Protein

Thermosome subunit beta

Gene

thsB

Organism
Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTKOD69014:G1G2A-2329-MONOMER
BRENDAi3.6.4.B10 5246

Names & Taxonomyi

Protein namesi
Recommended name:
Thermosome subunit beta
Alternative name(s):
Chaperonin subunit beta
Thermosome subunit 2
Gene namesi
Name:thsB
Synonyms:cpkB, ths
Ordered Locus Names:TK2303
OrganismiThermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1) (Pyrococcus kodakaraensis (strain KOD1))
Taxonomic identifieri69014 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaeThermococcus
Proteomesi
  • UP000000536 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001284111 – 546Thermosome subunit betaAdd BLAST546

Interactioni

Subunit structurei

Forms a Heterooligomeric complex of two stacked eight-membered rings.By similarity

GO - Molecular functioni

Protein-protein interaction databases

IntActiQ52500, 1 interactor
MINTiQ52500
STRINGi69014.TK2303

Structurei

3D structure databases

ProteinModelPortaliQ52500
SMRiQ52500
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.Curated

Phylogenomic databases

eggNOGiarCOG01257 Archaea
COG0459 LUCA
HOGENOMiHOG000226735
InParanoidiQ52500
KOiK22447
OMAiQFCLSPP
OrthoDBiPOG093Z02BT

Family and domain databases

CDDicd03343 cpn60, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
IPR012714 Thermosome_arc
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02339 thermosome_arch, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

Q52500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLAGQPVV ILPEGTQRYV GRDAQRLNIL AARIIAETVR TTLGPKGMDK
60 70 80 90 100
MLVDSLGDIV ITNDGATILD EMDIQHPAAK MMVEVAKTQD KEAGDGTTTA
110 120 130 140 150
VVIAGELLRK AEELLDQNIH PSIIIKGYAL AAEKAQEILD EIAKDVDVED
160 170 180 190 200
REILKKAAVT SITGKAAEEE REYLAEIAVE AVKQVAEKVG ETYKVDLDNI
210 220 230 240 250
KFEKKEGGSV KDTQLIKGVV IDKEVVHPGM PKRVEGAKIA LINEALEVKE
260 270 280 290 300
TETDAEIRIT SPEQLQAFLE QEEKMLREMV DKIKEVGANV VFVQKGIDDL
310 320 330 340 350
AQHYLAKYGI MAVRRVKKSD MEKLAKATGA KIVTNVRDLT PEDLGEAELV
360 370 380 390 400
EQRKVAGENM IFVEGCKNPK AVTILIRGGT EHVVDEVERA LEDAVKVVKD
410 420 430 440 450
IVEDGKIVAA GGAPEIELAI RLDEYAKEVG GKEQLAIEAF AEALKVIPRT
460 470 480 490 500
LAENAGLDPI ETLVKVIAAH KEKGPTIGVD VFEGEPADML ERGVIAPVRV
510 520 530 540
PKQAIKSASE AAIMILRIDD VIAASKLEKD KEGGKGGSED FGSDLD
Length:546
Mass (Da):59,158
Last modified:November 1, 1996 - v1
Checksum:i866191077CBD8E18
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D29672 Genomic DNA Translation: BAA06143.1
AP006878 Genomic DNA Translation: BAD86492.1
PIRiS61294
RefSeqiWP_011251253.1, NC_006624.1

Genome annotation databases

EnsemblBacteriaiBAD86492; BAD86492; TK2303
GeneIDi3233720
KEGGitko:TK2303
PATRICifig|69014.16.peg.2258

Similar proteinsi

Entry informationi

Entry nameiTHSB_THEKO
AccessioniPrimary (citable) accession number: Q52500
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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