UniProtKB - Q51743 (Q51743_PSEFL)
Protein
Submitted name:
Iron-sulfur protein large subunit of cumene dioxygenase
Gene
cumA1
Organism
Pseudomonas fluorescens
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 101 | Iron-sulfur (2Fe-2S)Combined sources | 1 | |
Metal bindingi | 103 | Iron-sulfur (2Fe-2S); via pros nitrogenCombined sources | 1 | |
Metal bindingi | 121 | Iron-sulfur (2Fe-2S)Combined sources | 1 | |
Metal bindingi | 124 | Iron-sulfur (2Fe-2S); via pros nitrogenCombined sources | 1 | |
Metal bindingi | 126 | Iron-sulfur (2Fe-2S)Combined sources | 1 | |
Metal bindingi | 234 | Iron; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 240 | Iron; via tele nitrogenCombined sources | 1 | |
Metal bindingi | 388 | IronCombined sources | 1 |
GO - Molecular functioni
- 2 iron, 2 sulfur cluster binding Source: UniProtKB-KW
- dioxygenase activity Source: UniProtKB-KW
- iron ion binding Source: InterPro
GO - Biological processi
- aromatic compound catabolic process Source: UniProtKB-KW
Keywordsi
Molecular function | DioxygenaseImportedARBA annotation, Oxidoreductase |
Biological process | Aromatic hydrocarbons catabolismARBA annotation |
Ligand | 2Fe-2SCombined sourcesARBA annotation, Iron, Iron-sulfur, Metal-binding |
Names & Taxonomyi
Protein namesi | Submitted name: Iron-sulfur protein large subunit of cumene dioxygenaseImported |
Gene namesi | Name:cumA1Imported |
Organismi | Pseudomonas fluorescensImported |
Taxonomic identifieri | 294 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas › |
PTM / Processingi
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 145 ↔ 152 | Combined sources |
Structurei
3D structure databases
SMRi | Q51743 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q51743 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 59 – 141 | RieskeInterPro annotationAdd BLAST | 83 |
Sequence similaritiesi
Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family.ARBA annotation
Family and domain databases
CDDi | cd08881, RHO_alpha_C_NDO-like, 1 hit |
Gene3Di | 2.102.10.10, 1 hit |
InterProi | View protein in InterPro IPR043266, RHO_NdoB-like_C IPR017941, Rieske_2Fe-2S IPR036922, Rieske_2Fe-2S_sf IPR015881, Ring-hydroxy_dOase_2Fe2S_BS IPR015879, Ring_hydroxy_dOase_asu_C_dom IPR001663, Rng_hydr_dOase-A |
Pfami | View protein in Pfam PF00355, Rieske, 1 hit PF00848, Ring_hydroxyl_A, 1 hit |
PRINTSi | PR00090, RNGDIOXGNASE |
SUPFAMi | SSF50022, SSF50022, 1 hit |
PROSITEi | View protein in PROSITE PS51296, RIESKE, 1 hit PS00570, RING_HYDROXYL_ALPHA, 1 hit |
i Sequence
Sequence statusi: Complete.
Q51743-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSSIINKEVQ EAPLKWVKNW SDEEIKALVD EEKGLLDPRI FSDQDLYEIE
60 70 80 90 100
LERVFARSWL LLGHEGHIPK AGDYLTTYMG EDPVIVVRQK DRSIKVFLNQ
110 120 130 140 150
CRHRGMRIER SDFGNAKSFT CTYHGWAYDT AGNLVNVPYE KEAFCDKKEG
160 170 180 190 200
DCGFDKADWG PLQARVDTYK GLIFANWDTE APDLKTYLSD ATPYMDVMLD
210 220 230 240 250
RTEAVTQVIT GMQKTVIPCN WKFAAEQFCS DMYHAGTMAH LSGVLSSLPP
260 270 280 290 300
EMDLSQVKLP SSGNQFRAKW GGHGTGWFND DFALLQAIMG PKVVDYWTKG
310 320 330 340 350
PAAERAKERL GKVLPADRMV AQHMTIFPTC SFLPGINTVR TWHPRGPNEI
360 370 380 390 400
EVWSFIVVDA DAPEDIKEEY RRKNIFTFNQ GGTYEQDDGE NWVEVQRGLR
410 420 430 440 450
GYKARSRPLC AQMGAGVPNK NNPEFPGKTS YVYSEEAARG FYHHWSRMMS
EPSWDTLKS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D37828 Genomic DNA Translation: BAA07074.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | D37828 Genomic DNA Translation: BAA07074.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1WQL | X-ray | 2.20 | A | 1-459 | [»] | |
SMRi | Q51743 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
IntActi | Q51743, 1 interactor |
Miscellaneous databases
EvolutionaryTracei | Q51743 |
Family and domain databases
CDDi | cd08881, RHO_alpha_C_NDO-like, 1 hit |
Gene3Di | 2.102.10.10, 1 hit |
InterProi | View protein in InterPro IPR043266, RHO_NdoB-like_C IPR017941, Rieske_2Fe-2S IPR036922, Rieske_2Fe-2S_sf IPR015881, Ring-hydroxy_dOase_2Fe2S_BS IPR015879, Ring_hydroxy_dOase_asu_C_dom IPR001663, Rng_hydr_dOase-A |
Pfami | View protein in Pfam PF00355, Rieske, 1 hit PF00848, Ring_hydroxyl_A, 1 hit |
PRINTSi | PR00090, RNGDIOXGNASE |
SUPFAMi | SSF50022, SSF50022, 1 hit |
PROSITEi | View protein in PROSITE PS51296, RIESKE, 1 hit PS00570, RING_HYDROXYL_ALPHA, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q51743_PSEFL | |
Accessioni | Q51743Primary (citable) accession number: Q51743 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | October 7, 2020 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |