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Protein

Naphthalene 1,2-dioxygenase system, ferredoxin component

Gene

ndoA

Organism
Pseudomonas aeruginosa
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Component of the naphthalene dioxygenase (NDO) multicomponent enzyme system which catalyzes the incorporation of both atoms of molecular oxygen into naphthalene to form cis-(1R,2S)-dihydroxy-1,2-dihydronaphthalene. Functions as an intermediate electron transfer protein via a specific interaction with iron sulfur protein components (ISP) (NdoB and NdoC).By similarity

Cofactori

[2Fe-2S] clusterPROSITE-ProRule annotationBy similarityNote: Binds 1 [2Fe-2S] cluster per subunit.PROSITE-ProRule annotationBy similarity

Pathwayi: naphthalene degradation

This protein is involved in the pathway naphthalene degradation, which is part of Aromatic compound metabolism.By similarity
View all proteins of this organism that are known to be involved in the pathway naphthalene degradation and in Aromatic compound metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi45Iron-sulfur (2Fe-2S)PROSITE-ProRule annotationBy similarity1
Metal bindingi47Iron-sulfur (2Fe-2S); via pros nitrogenPROSITE-ProRule annotationBy similarity1
Metal bindingi64Iron-sulfur (2Fe-2S)PROSITE-ProRule annotationBy similarity1
Metal bindingi67Iron-sulfur (2Fe-2S); via pros nitrogenPROSITE-ProRule annotationBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processAromatic hydrocarbons catabolism, Electron transport, Transport
Ligand2Fe-2S, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

UniPathwayiUPA00082

Names & Taxonomyi

Protein namesi
Recommended name:
Naphthalene 1,2-dioxygenase system, ferredoxin componentBy similarity
Gene namesi
Name:ndoABy similarity
Synonyms:pahA2
OrganismiPseudomonas aeruginosa
Taxonomic identifieri287 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00002016912 – 104Naphthalene 1,2-dioxygenase system, ferredoxin componentAdd BLAST103

Interactioni

Subunit structurei

The naphthalene dioxygenase (NDO) multicomponent enzyme system is composed of an electron transfer component and a dioxygenase component (iron sulfur protein (ISP)). The electron transfer component is composed of a ferredoxin reductase (NdoR) and a ferredoxin (NdoA), and the dioxygenase component is formed of a heterohexamer (trimer of heterodimers) of three large alpha subunits (NdoB) and three small beta subunits (NdoC).By similarity

Structurei

3D structure databases

ProteinModelPortaliQ51493
SMRiQ51493
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 101RieskePROSITE-ProRule annotationAdd BLAST96

Sequence similaritiesi

Family and domain databases

Gene3Di2.102.10.10, 1 hit
InterProiView protein in InterPro
IPR017941 Rieske_2Fe-2S
IPR036922 Rieske_2Fe-2S_sf
PfamiView protein in Pfam
PF00355 Rieske, 1 hit
SUPFAMiSSF50022 SSF50022, 1 hit
PROSITEiView protein in PROSITE
PS51296 RIESKE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q51493-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEKWIDAVA LYEIPEGDVL GVTVEGKELA LYEVEGEIYA TDNLCTHGAA
60 70 80 90 100
RMSDGFLEGR EIECPLHQGR FDVCTGRALC APVTQNIKTY PVKIEGQRVM

IDLS
Length:104
Mass (Da):11,490
Last modified:January 23, 2007 - v3
Checksum:i33F6E5CB9C112F40
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D84146 Genomic DNA Translation: BAA12239.1

Entry informationi

Entry nameiNDOA_PSEAI
AccessioniPrimary (citable) accession number: Q51493
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: January 23, 2007
Last modified: November 22, 2017
This is version 71 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

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