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Entry version 116 (07 Apr 2021)
Sequence version 3 (27 Jul 2011)
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Protein

Cytosolic phospholipase A2 zeta

Gene

Pla2g4f

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Has calcium-dependent phospholipase and lysophospholipase activities with a potential role in membrane lipid remodeling and biosynthesis of lipid mediators (PubMed:17293613, PubMed:15866882). Preferentially hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids (phospholipase A2 activity) (PubMed:17293613, PubMed:15866882). Selectively hydrolyzes sn-2 arachidonoyl group from membrane phospholipids, providing the precursor for eicosanoid biosynthesis (PubMed:15866882, PubMed:17293613). In myocardial mitochondria, plays a major role in arachidonate release that is metabolically channeled to the formation of cardioprotective eicosanoids, epoxyeicosatrienoates (EETs) (By similarity).By similarity2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Ca2+PROSITE-ProRule annotation2 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes regulatory mechanisms for enzymes, transporters or microbial transcription factors, and reports the components which regulate (by activation or inhibition) the reaction.<p><a href='/help/activity_regulation' target='_top'>More...</a></p>Activity regulationi

Stimulated by cytosolic Ca2+.2 Publications

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi60Calcium 1PROSITE-ProRule annotation1
Metal bindingi60Calcium 2PROSITE-ProRule annotation1
Metal bindingi66Calcium 1PROSITE-ProRule annotation1
Metal bindingi116Calcium 1PROSITE-ProRule annotation1
Metal bindingi116Calcium 2PROSITE-ProRule annotation1
Metal bindingi118Calcium 1PROSITE-ProRule annotation1
Metal bindingi118Calcium 2PROSITE-ProRule annotation1
Metal bindingi123Calcium 2PROSITE-ProRule annotation1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei393NucleophileBy similarity1
Active sitei685Proton acceptorBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHydrolase
Biological processLipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism
LigandCalcium, Metal-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-1482788, Acyl chain remodelling of PC
R-MMU-1482801, Acyl chain remodelling of PS
R-MMU-1482839, Acyl chain remodelling of PE
R-MMU-1482922, Acyl chain remodelling of PI
R-MMU-1482925, Acyl chain remodelling of PG
R-MMU-1483115, Hydrolysis of LPC

Chemistry databases

SwissLipids knowledge resource for lipid biology

More...
SwissLipidsi
SLP:000001085

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cytosolic phospholipase A2 zeta (EC:3.1.1.42 Publications)
Short name:
cPLA2-zeta
Alternative name(s):
Phospholipase A2 group IVF
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Pla2g4f
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2685493, Pla2g4f

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membrane, Cytoplasm, Membrane, Mitochondrion

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002470281 – 855Cytosolic phospholipase A2 zetaAdd BLAST855

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q50L41

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q50L41

PRoteomics IDEntifications database

More...
PRIDEi
Q50L41

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
294373

PTM databases

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q50L41

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Strongly expressed in thyroid, expressed at intermediate level in stomach and at very low level in large intestine and prostate.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000046971, Expressed in skeletal muscle tissue and 133 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q50L41, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000062607

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q50L41, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q50L41

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 145C2PROSITE-ProRule annotationAdd BLAST119
Domaini304 – 855PLA2cPROSITE-ProRule annotationAdd BLAST552

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The N-terminal C2 domain associates with lipid membranes upon calcium binding. It modulates enzyme activity by presenting the active site to its substrate in response to elevations of cytosolic Ca2+ (By similarity).By similarity

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1028, Eukaryota
KOG1325, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT01000000214502

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011663_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q50L41

Identification of Orthologs from Complete Genome Data

More...
OMAi
GDFAEWC

Database of Orthologous Groups

More...
OrthoDBi
302848at2759

TreeFam database of animal gene trees

More...
TreeFami
TF325228

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04036, C2_cPLA2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.150, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016035, Acyl_Trfase/lysoPLipase
IPR041847, C2_cPLA2
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR040723, cPLA2_C2
IPR002642, LysoPLipase_cat_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00168, C2, 1 hit
PF18695, cPLA2_C2, 1 hit
PF01735, PLA2_B, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00239, C2, 1 hit
SM00022, PLAc, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52151, SSF52151, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50004, C2, 1 hit
PS51210, PLA2C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q50L41-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPWTLQPKWL AGKGLPLLGA ILLRKTEKSE PQWKHRRQET HPYYDLQVKV
60 70 80 90 100
LRARNIQHTD KLSKADCYVR LWLPTASVSP SQTRTVVNSS DPEWNETFPY
110 120 130 140 150
QIHGAVKNVL ELALYDEDVL DSDNVFSILF DTSTLQLGQP CTKNFTRQQD
160 170 180 190 200
PKELEVEFTL EKSQTPASEV VTNGVLVAHP CLRIQGTVTG DKTASLGELG
210 220 230 240 250
SRQIQLAVPG AYEKPQPLQP TSEPGLPVNF TFHVNPVLSP KLHIKLQEQL
260 270 280 290 300
QVFHSGPSDE LEAQTSKMDK ASILLSSLPL NEELTKLVDL EEGQQVSLRM
310 320 330 340 350
KADMSSSGDL DLRLGFDLCD GEQEFLDKRK QVASKALQRV MGLSEALHCD
360 370 380 390 400
QVPVVAVLGS GGGTRAMTSL YGSLAGLQEL GLLDAVTYLS GVSGSSWCIS
410 420 430 440 450
TLYRDPSWSQ KALQGPIKYA SERVCSSKIG MLSPKQFEYY SREKRAWESR
460 470 480 490 500
GHSMSFTDLW GLIIEYFLNQ EENPAKLSDQ QETVSQGQNP YPIYASINVH
510 520 530 540 550
KNISGDDFAE WCEFTPYEVG FPKYGAYVPT ELFGSEFFMG RLLHFWPEPR
560 570 580 590 600
ICYLQGMWGS AFAASLYEIF LKLGGLSLSF LDWHRGSVSV TDDWPKLRKQ
610 620 630 640 650
DPTRLPTRLF TPMSSFSQAV LDIFTSRITC AQTFNFTRGL CMYKDYTARK
660 670 680 690 700
DFVVSEDAWH SHNYGYPDAC PNQLTPMKDF LSLVDGGFAI NSPFPLVLQP
710 720 730 740 750
QRAVDLIVSF DYSLEGPFEV LQVTEKYCRD RGIPFPRIEV DPKDSEDPRE
760 770 780 790 800
CYLFAEAEDP CSPIVLHFPL VNRTFRTHLA PGVERQTAEE KAFGDFIING
810 820 830 840 850
PDTAYGMMDF TYEPKEFDRL VTLSRYNVLN NKETIRHALQ LALDRRRQAG

GRVGG
Length:855
Mass (Da):96,364
Last modified:July 27, 2011 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4F839C857E136D6F
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH39947 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti99P → H in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti132T → M in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti234V → M in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti297S → T in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti507D → Y in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti507D → Y in AAH46400 (PubMed:15489334).Curated1
Sequence conflicti526A → V in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti526A → V in AAH46400 (PubMed:15489334).Curated1
Sequence conflicti755A → T in AAH39947 (PubMed:15489334).Curated1
Sequence conflicti755A → T in AAH46400 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB195278 mRNA Translation: BAD98154.1
AL844608 Genomic DNA No translation available.
BC039947 mRNA Translation: AAH39947.1 Different initiation.
BC046400 mRNA Translation: AAH46400.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS16618.1

NCBI Reference Sequences

More...
RefSeqi
NP_001019316.1, NM_001024145.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000054651; ENSMUSP00000062607; ENSMUSG00000046971

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
271844

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:271844

UCSC genome browser

More...
UCSCi
uc008lvi.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB195278 mRNA Translation: BAD98154.1
AL844608 Genomic DNA No translation available.
BC039947 mRNA Translation: AAH39947.1 Different initiation.
BC046400 mRNA Translation: AAH46400.1
CCDSiCCDS16618.1
RefSeqiNP_001019316.1, NM_001024145.2

3D structure databases

SMRiQ50L41
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000062607

Chemistry databases

SwissLipidsiSLP:000001085

PTM databases

PhosphoSitePlusiQ50L41

Proteomic databases

MaxQBiQ50L41
PaxDbiQ50L41
PRIDEiQ50L41
ProteomicsDBi294373

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
42117, 61 antibodies

Genome annotation databases

EnsembliENSMUST00000054651; ENSMUSP00000062607; ENSMUSG00000046971
GeneIDi271844
KEGGimmu:271844
UCSCiuc008lvi.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
255189
MGIiMGI:2685493, Pla2g4f

Phylogenomic databases

eggNOGiKOG1028, Eukaryota
KOG1325, Eukaryota
GeneTreeiENSGT01000000214502
HOGENOMiCLU_011663_0_0_1
InParanoidiQ50L41
OMAiGDFAEWC
OrthoDBi302848at2759
TreeFamiTF325228

Enzyme and pathway databases

ReactomeiR-MMU-1482788, Acyl chain remodelling of PC
R-MMU-1482801, Acyl chain remodelling of PS
R-MMU-1482839, Acyl chain remodelling of PE
R-MMU-1482922, Acyl chain remodelling of PI
R-MMU-1482925, Acyl chain remodelling of PG
R-MMU-1483115, Hydrolysis of LPC

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
271844, 1 hit in 52 CRISPR screens

Protein Ontology

More...
PROi
PR:Q50L41
RNActiQ50L41, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000046971, Expressed in skeletal muscle tissue and 133 other tissues
GenevisibleiQ50L41, MM

Family and domain databases

CDDicd04036, C2_cPLA2, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR016035, Acyl_Trfase/lysoPLipase
IPR041847, C2_cPLA2
IPR000008, C2_dom
IPR035892, C2_domain_sf
IPR040723, cPLA2_C2
IPR002642, LysoPLipase_cat_dom
PfamiView protein in Pfam
PF00168, C2, 1 hit
PF18695, cPLA2_C2, 1 hit
PF01735, PLA2_B, 1 hit
SMARTiView protein in SMART
SM00239, C2, 1 hit
SM00022, PLAc, 1 hit
SUPFAMiSSF52151, SSF52151, 1 hit
PROSITEiView protein in PROSITE
PS50004, C2, 1 hit
PS51210, PLA2C, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiPA24F_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q50L41
Secondary accession number(s): A2AQJ2, Q80VQ8, Q80VV9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 27, 2011
Last modified: April 7, 2021
This is version 116 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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