UniProtKB - Q50HX4 (Q50HX4_MOUSE)
Protein
Ras-related protein Rab-14
Gene
Rab14
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- GDP binding Source: Ensembl
- GTPase activity Source: Ensembl
- GTP binding Source: UniProtKB-KW
- myosin V binding Source: Ensembl
GO - Biological processi
- defense response to bacterium Source: InterPro
- endocytic recycling Source: Ensembl
- Golgi to endosome transport Source: InterPro
- phagosome maturation Source: InterPro
- regulation of protein localization Source: Ensembl
Keywordsi
Ligand | GTP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Ras-related protein Rab-14ARBA annotation |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:1915615, Rab14 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane ARBA annotation; Lipid-anchor ARBA annotation; Cytoplasmic side ARBA annotation
- trans-Golgi network membrane ARBA annotation; Lipid-anchor ARBA annotation; Cytoplasmic side ARBA annotation
Endosome
- Early endosome membrane ARBA annotation; Lipid-anchor ARBA annotation; Cytoplasmic side ARBA annotation
- Endosome membrane ARBA annotation; Lipid-anchor ARBA annotation; Cytoplasmic side ARBA annotation
- Recycling endosome ARBA annotation
Other locations
- phagosome ARBA annotation
Cytosol
- cytosol Source: GOC
Endosome
- early endosome membrane Source: UniProtKB-SubCell
- recycling endosome Source: UniProtKB-SubCell
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
- trans-Golgi network Source: InterPro
Other locations
- phagocytic vesicle Source: UniProtKB-SubCell
Keywords - Cellular componenti
MembraneARBA annotationPTM / Processingi
Keywords - PTMi
Lipoprotein, PrenylationARBA annotationProteomic databases
EPDi | Q50HX4 |
PeptideAtlasi | Q50HX4 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000026878, Expressed in secondary oocyte and 311 other tissues |
ExpressionAtlasi | Q50HX4, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 188 – 215 | DisorderedSequence analysisAdd BLAST | 28 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 125 – 145 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
OMAi | QRDVTFE |
OrthoDBi | 1146851at2759 |
Family and domain databases
CDDi | cd04122, Rab14, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR030702, Rab14 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
PANTHERi | PTHR24073:SF1098, PTHR24073:SF1098, 1 hit |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q50HX4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATAPYNYSY IFKYIIIGDM GVGKSCLLHQ FTEKKFMADC PHTIGVEFGT
60 70 80 90 100
RIIEVSGQKI KLQIWDTAGQ ERFRAVTRSY YRGAAGALMV YDITRRSTYN
110 120 130 140 150
HLSSWLTDAR NLTNPNTVII LIGNKADLEA QRDVTYEEAK QFAEENGLLF
160 170 180 190 200
LEASAKTGEN VEDAFLEAAK KIYQNIQDGS LDLNAAESGV QHKPSAPQGG
210
RLTSEPQPQR EGCGC
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK133963 mRNA Translation: BAE21957.1 AK160859 mRNA Translation: BAE36051.1 AK165812 mRNA Translation: BAE38391.1 AK168551 mRNA Translation: BAE40426.1 AK168867 mRNA Translation: BAE40686.1 AK169396 mRNA Translation: BAE41143.1 AB232609 mRNA Translation: BAF02871.1 AJ968955 mRNA Translation: CAI92125.1 |
RefSeqi | NP_080973.1, NM_026697.3 |
Genome annotation databases
GeneIDi | 68365 |
KEGGi | mmu:68365 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK133963 mRNA Translation: BAE21957.1 AK160859 mRNA Translation: BAE36051.1 AK165812 mRNA Translation: BAE38391.1 AK168551 mRNA Translation: BAE40426.1 AK168867 mRNA Translation: BAE40686.1 AK169396 mRNA Translation: BAE41143.1 AB232609 mRNA Translation: BAF02871.1 AJ968955 mRNA Translation: CAI92125.1 |
RefSeqi | NP_080973.1, NM_026697.3 |
3D structure databases
SMRi | Q50HX4 |
ModBasei | Search... |
Proteomic databases
EPDi | Q50HX4 |
PeptideAtlasi | Q50HX4 |
Protocols and materials databases
Antibodypediai | 15967, 159 antibodies |
Genome annotation databases
GeneIDi | 68365 |
KEGGi | mmu:68365 |
Organism-specific databases
CTDi | 51552 |
MGIi | MGI:1915615, Rab14 |
Phylogenomic databases
OMAi | QRDVTFE |
OrthoDBi | 1146851at2759 |
Miscellaneous databases
BioGRID-ORCSi | 68365, 3 hits in 12 CRISPR screens |
ChiTaRSi | Rab14, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000026878, Expressed in secondary oocyte and 311 other tissues |
ExpressionAtlasi | Q50HX4, baseline and differential |
Family and domain databases
CDDi | cd04122, Rab14, 1 hit |
InterProi | View protein in InterPro IPR027417, P-loop_NTPase IPR030702, Rab14 IPR005225, Small_GTP-bd_dom IPR001806, Small_GTPase |
PANTHERi | PTHR24073:SF1098, PTHR24073:SF1098, 1 hit |
Pfami | View protein in Pfam PF00071, Ras, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00231, small_GTP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q50HX4_MOUSE | |
Accessioni | Q50HX4Primary (citable) accession number: Q50HX4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | December 2, 2020 | |
This is version 158 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |