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Entry version 79 (08 May 2019)
Sequence version 2 (26 Feb 2008)
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Protein

Protein FAM160A1

Gene

Fam160a1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM160A1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2444746 Fam160a1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003195791 – 1081Protein FAM160A1Add BLAST1081

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q505K2

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q505K2

PeptideAtlas

More...
PeptideAtlasi
Q505K2

PRoteomics IDEntifications database

More...
PRIDEi
Q505K2

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q505K2

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q505K2

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000051000 Expressed in 126 organ(s), highest expression level in oocyte

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q505K2 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q505K2 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000113235

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi489 – 497Poly-Pro9

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the UPF0518 family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3695 Eukaryota
ENOG410XY4X LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000182936

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000112444

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q505K2

Identification of Orthologs from Complete Genome Data

More...
OMAi
LFRVDMS

Database of Orthologous Groups

More...
OrthoDBi
141539at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q505K2

TreeFam database of animal gene trees

More...
TreeFami
TF313941

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR019384 RetinoicA-induced_16-like

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10257 RAI16-like, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q505K2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMSSVSTESK LQQAVSLKGV DPETCMIVFK NHWAQVVKIL EKHDPLKNTQ
60 70 80 90 100
AKYGSIPPDE ASAVQNYVEH MLFLLIEEQA KDAAMGPILE FVVCENIMEK
110 120 130 140 150
LFLWSLRREF TDETKLEQLK MYEMLVTQSY QPLLHHKPIL KPLMMLLSSC
160 170 180 190 200
SGTATPAVEG KLVVLLNQLC SILAKDPSIL ELFFHTSEDQ GAANFLIFSL
210 220 230 240 250
LIPFIHREGT VGQQARDALL FIMSLSAENS MVANHIVENT YFCPVLATGL
260 270 280 290 300
SGLYSSLPTK LEEKGEDWHC ILKDDWLLLP ALVQFMNSLE FCNAVIQVAH
310 320 330 340 350
PLIRTQLVSY IYNGFLVPVL APALHKVTVE EVMTTTAYLD LFLRSISEPA
360 370 380 390 400
LLEIFLRFIL LHRHENVHIL DTLTSRINTP FRLCVVSLAL FRTLIGLHCE
410 420 430 440 450
DVMLQLVLRY LVPCNHMMLS QRWAVKERDC YSVSAAKLLA LTPVCCASGI
460 470 480 490 500
TLTLGNQERD YILWSKCMHD GSGSEEQLLP ETPCSPSSPS PPPPPAPAAC
510 520 530 540 550
IVEYGKALDI SYLQYLWEAH TNILHCMRDC RVWSALYDGD SPDPETFLQS
560 570 580 590 600
LSEESRENSG HPEARLPQQS VRTSGQTKDK SQSELEWDDS YDTGISSGAD
610 620 630 640 650
VGSPGPDDEV ETPAPPAPID PPKHIQEMKK NAILLFKGSY IEESDFQDDV
660 670 680 690 700
MVYRLCAEKD TEDTTEPQKD TSEPQGDTLE PLEDTSEQQE DTSEQLEDTS
710 720 730 740 750
ELQEDTAEPQ GDTADPTAEA QPKLQPEAQS LPTSNGPLSS PDPETESQPS
760 770 780 790 800
RESSDLCQNT FSEAKPENEP GVALALDSEL IATTFEAEPQ SELAVVSTES
810 820 830 840 850
EDFIAQYDQI IQELDSGTEG LTEQSIPISE PSLLTQQEER REECKEEEDD
860 870 880 890 900
DFDSLMAATP AVEAGSSPFG VGEDTAFSSR HPVRTQSTPF TGPFISVVLS
910 920 930 940 950
KLENMLENSL HVNLLLIGII TQLASYPQPL LRSFLLNTNM VFQPSVRSLY
960 970 980 990 1000
QVLASVKNKI EQFASVERDF PGLLIQAQQY LLFRVDMSDM APAALTKDPI
1010 1020 1030 1040 1050
QEISRPESDK TLLDGPPRVL QPFLGNRAKV TRAPPNLPLP VKNTMLAAAL
1060 1070 1080
FPEFLKELAA LAQEHSILCY KILGDFEDSC C
Length:1,081
Mass (Da):120,219
Last modified:February 26, 2008 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2D8528C959F7B499
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PX40E9PX40_MOUSE
Protein FAM160A1
Fam160a1
226Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAC29618 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC102338 Genomic DNA No translation available.
BC094511 mRNA Translation: AAH94511.1
AK036881 mRNA Translation: BAC29618.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS17442.2

NCBI Reference Sequences

More...
RefSeqi
NP_766270.2, NM_172682.3
XP_006501396.1, XM_006501333.3
XP_011238384.1, XM_011240082.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000094148; ENSMUSP00000091700; ENSMUSG00000051000
ENSMUST00000118408; ENSMUSP00000113235; ENSMUSG00000051000

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
229488

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:229488

UCSC genome browser

More...
UCSCi
uc008pqu.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC102338 Genomic DNA No translation available.
BC094511 mRNA Translation: AAH94511.1
AK036881 mRNA Translation: BAC29618.1 Different initiation.
CCDSiCCDS17442.2
RefSeqiNP_766270.2, NM_172682.3
XP_006501396.1, XM_006501333.3
XP_011238384.1, XM_011240082.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000113235

PTM databases

iPTMnetiQ505K2
PhosphoSitePlusiQ505K2

Proteomic databases

MaxQBiQ505K2
PaxDbiQ505K2
PeptideAtlasiQ505K2
PRIDEiQ505K2

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000094148; ENSMUSP00000091700; ENSMUSG00000051000
ENSMUST00000118408; ENSMUSP00000113235; ENSMUSG00000051000
GeneIDi229488
KEGGimmu:229488
UCSCiuc008pqu.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
729830
MGIiMGI:2444746 Fam160a1

Phylogenomic databases

eggNOGiKOG3695 Eukaryota
ENOG410XY4X LUCA
GeneTreeiENSGT00950000182936
HOGENOMiHOG000112444
InParanoidiQ505K2
OMAiLFRVDMS
OrthoDBi141539at2759
PhylomeDBiQ505K2
TreeFamiTF313941

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q505K2

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000051000 Expressed in 126 organ(s), highest expression level in oocyte
ExpressionAtlasiQ505K2 baseline and differential
GenevisibleiQ505K2 MM

Family and domain databases

InterProiView protein in InterPro
IPR019384 RetinoicA-induced_16-like
PfamiView protein in Pfam
PF10257 RAI16-like, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF16A1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q505K2
Secondary accession number(s): Q8BZ23
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: February 26, 2008
Last modified: May 8, 2019
This is version 79 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries
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