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UniProtKB - Q505F5 (LRC47_MOUSE)
Protein
Leucine-rich repeat-containing protein 47
Gene
Lrrc47
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- phenylalanine-tRNA ligase activity Source: InterPro
- RNA binding Source: InterPro
GO - Biological processi
- phenylalanyl-tRNA aminoacylation Source: InterPro
Names & Taxonomyi
Protein namesi | Recommended name: Leucine-rich repeat-containing protein 47 |
Gene namesi | Name:Lrrc47 Synonyms:Kiaa1185 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1920196, Lrrc47 |
VEuPathDBi | HostDB:ENSMUSG00000029028 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000223927 | 1 – 581 | Leucine-rich repeat-containing protein 47Add BLAST | 581 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 314 | PhosphoserineBy similarity | 1 | |
Modified residuei | 430 | PhosphoserineBy similarity | 1 | |
Modified residuei | 519 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q505F5 |
jPOSTi | Q505F5 |
MaxQBi | Q505F5 |
PaxDbi | Q505F5 |
PRIDEi | Q505F5 |
ProteomicsDBi | 252670 |
2D gel databases
REPRODUCTION-2DPAGEi | Q505F5 |
PTM databases
iPTMneti | Q505F5 |
PhosphoSitePlusi | Q505F5 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000029028, Expressed in blastocyst and 273 other tissues |
ExpressionAtlasi | Q505F5, baseline and differential |
Genevisiblei | Q505F5, MM |
Interactioni
Protein-protein interaction databases
BioGRIDi | 215663, 13 interactors |
IntActi | Q505F5, 5 interactors |
MINTi | Q505F5 |
STRINGi | 10090.ENSMUSP00000133124 |
Miscellaneous databases
RNActi | Q505F5, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 78 – 97 | LRR 1Add BLAST | 20 | |
Repeati | 102 – 123 | LRR 2Add BLAST | 22 | |
Repeati | 132 – 154 | LRR 3Add BLAST | 23 | |
Repeati | 156 – 177 | LRR 4Add BLAST | 22 | |
Repeati | 182 – 204 | LRR 5Add BLAST | 23 | |
Repeati | 205 – 227 | LRR 6Add BLAST | 23 | |
Repeati | 228 – 248 | LRR 7Add BLAST | 21 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 262 – 301 | DisorderedSequence analysisAdd BLAST | 40 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 401 – 436 | Sequence analysisAdd BLAST | 36 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 265 – 283 | Basic and acidic residuesSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Coiled coil, Leucine-rich repeat, RepeatPhylogenomic databases
eggNOGi | KOG2472, Eukaryota |
GeneTreei | ENSGT00530000063489 |
HOGENOMi | CLU_034522_0_0_1 |
InParanoidi | Q505F5 |
OMAi | YDVKPPT |
OrthoDBi | 1021451at2759 |
PhylomeDBi | Q505F5 |
Family and domain databases
Gene3Di | 3.50.40.10, 1 hit 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR005146, B3/B4_tRNA-bd IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR045060, Phe-tRNA-ligase_IIc_bsu IPR020825, Phe-tRNA_synthase-like_B3/B4 |
PANTHERi | PTHR10947, PTHR10947, 1 hit |
Pfami | View protein in Pfam PF03483, B3_4, 1 hit PF13855, LRR_8, 2 hits |
SMARTi | View protein in SMART SM00873, B3_4, 1 hit SM00369, LRR_TYP, 5 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 6 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All
Q505F5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAAAMAVSE AWPELELAER ERRRELLLTG PGLEERVKAA GGRLPPRLFT
60 70 80 90 100
LPLLHYLEVS GCGSLRAPGP GLAQGLPQLH SLVLRRNALG PGLSPELGPL
110 120 130 140 150
PALRVLDLSG NALETLPPGE GLGPAEPPGL PQLQSLNLSG NRLRELPADL
160 170 180 190 200
ARCAPRLQSL NLTGNRLDAF PPELFRPGAL PLLSELAAAD NCLRELSPDI
210 220 230 240 250
AHLASLKTLD LSNNQLTEIP AELADCPKLK EINFRGNRLR DKRLEKMVGG
260 270 280 290 300
CQTKSILEYL RAGGRGGRSK GRQEASEKED RKKRRERKQH RESGEGEEEV
310 320 330 340 350
ADSARLMLKV LHVSENPTPL TVRVSPEVKD VRPYIVGAIV RGMDLQPGNA
360 370 380 390 400
LRRFLNSQTK LHDDLCEKRT AATIATHDLQ AVRGPLLYAA RPPEDLKIVP
410 420 430 440 450
LGRKEAKAKE LVRQLQLEAE EQRKQKKRQS VSGLHRYLHL LDGKENYPCL
460 470 480 490 500
VDAEGDVISF PPITNSEKTK IKKTTCNLFL EVTSATSLQL CKDIMDSLIL
510 520 530 540 550
RMAELSKSTS ENKEEDMLSG TEADAGCGLS DPNLTLSSGK DGQCPLVVEQ
560 570 580
VRVVDLEGSL KVVYPSKTDL ITLPPHVTVV R
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE9PV22 | E9PV22_MOUSE | Leucine-rich repeat-containing prot... | Lrrc47 | 603 | Annotation score: | ||
F6YT33 | F6YT33_MOUSE | Leucine-rich repeat-containing prot... | Lrrc47 | 79 | Annotation score: | ||
F6Z4L9 | F6Z4L9_MOUSE | Leucine-rich repeat-containing prot... | Lrrc47 | 123 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 312 | H → Y in BAE32909 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 487 | S → N in BAC98116 (PubMed:14621295).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK013512 mRNA Translation: BAB28889.1 AK154897 mRNA Translation: BAE32909.1 BC094573 mRNA Translation: AAH94573.1 AK129306 mRNA Translation: BAC98116.1 |
CCDSi | CCDS19006.1 |
RefSeqi | NP_957678.1, NM_201226.1 |
Genome annotation databases
Ensembli | ENSMUST00000030894; ENSMUSP00000030894; ENSMUSG00000029028 |
GeneIDi | 72946 |
KEGGi | mmu:72946 |
UCSCi | uc008way.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK013512 mRNA Translation: BAB28889.1 AK154897 mRNA Translation: BAE32909.1 BC094573 mRNA Translation: AAH94573.1 AK129306 mRNA Translation: BAC98116.1 |
CCDSi | CCDS19006.1 |
RefSeqi | NP_957678.1, NM_201226.1 |
3D structure databases
AlphaFoldDBi | Q505F5 |
SMRi | Q505F5 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 215663, 13 interactors |
IntActi | Q505F5, 5 interactors |
MINTi | Q505F5 |
STRINGi | 10090.ENSMUSP00000133124 |
PTM databases
iPTMneti | Q505F5 |
PhosphoSitePlusi | Q505F5 |
2D gel databases
REPRODUCTION-2DPAGEi | Q505F5 |
Proteomic databases
EPDi | Q505F5 |
jPOSTi | Q505F5 |
MaxQBi | Q505F5 |
PaxDbi | Q505F5 |
PRIDEi | Q505F5 |
ProteomicsDBi | 252670 |
Protocols and materials databases
Antibodypediai | 1623, 28 antibodies from 13 providers |
DNASUi | 72946 |
Genome annotation databases
Ensembli | ENSMUST00000030894; ENSMUSP00000030894; ENSMUSG00000029028 |
GeneIDi | 72946 |
KEGGi | mmu:72946 |
UCSCi | uc008way.1, mouse |
Organism-specific databases
CTDi | 57470 |
MGIi | MGI:1920196, Lrrc47 |
VEuPathDBi | HostDB:ENSMUSG00000029028 |
Rougei | Search... |
Phylogenomic databases
eggNOGi | KOG2472, Eukaryota |
GeneTreei | ENSGT00530000063489 |
HOGENOMi | CLU_034522_0_0_1 |
InParanoidi | Q505F5 |
OMAi | YDVKPPT |
OrthoDBi | 1021451at2759 |
PhylomeDBi | Q505F5 |
Miscellaneous databases
BioGRID-ORCSi | 72946, 1 hit in 72 CRISPR screens |
PROi | PR:Q505F5 |
RNActi | Q505F5, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000029028, Expressed in blastocyst and 273 other tissues |
ExpressionAtlasi | Q505F5, baseline and differential |
Genevisiblei | Q505F5, MM |
Family and domain databases
Gene3Di | 3.50.40.10, 1 hit 3.80.10.10, 2 hits |
InterProi | View protein in InterPro IPR005146, B3/B4_tRNA-bd IPR001611, Leu-rich_rpt IPR003591, Leu-rich_rpt_typical-subtyp IPR032675, LRR_dom_sf IPR045060, Phe-tRNA-ligase_IIc_bsu IPR020825, Phe-tRNA_synthase-like_B3/B4 |
PANTHERi | PTHR10947, PTHR10947, 1 hit |
Pfami | View protein in Pfam PF03483, B3_4, 1 hit PF13855, LRR_8, 2 hits |
SMARTi | View protein in SMART SM00873, B3_4, 1 hit SM00369, LRR_TYP, 5 hits |
PROSITEi | View protein in PROSITE PS51450, LRR, 6 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | LRC47_MOUSE | |
Accessioni | Q505F5Primary (citable) accession number: Q505F5 Secondary accession number(s): Q3U380, Q6ZPW2, Q9CUZ0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 21, 2006 |
Last sequence update: | June 7, 2005 | |
Last modified: | May 25, 2022 | |
This is version 129 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot