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UniProtKB - Q505F4 (Q505F4_MOUSE)
Protein
Submitted name:
Zinc finger protein 280B
Gene
Zfp280b
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- regulation of transcription, DNA-templated Source: GO_Central
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: Zinc finger protein 280BImported |
Gene namesi | |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1927865, Zfp280b |
VEuPathDBi | HostDB:ENSMUSG00000049764 |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationExpressioni
Gene expression databases
Bgeei | ENSMUSG00000049764, Expressed in zygote and 243 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 334 – 362 | C2H2-typeInterPro annotationAdd BLAST | 29 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 30 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 63 – 142 | DisorderedSequence analysisAdd BLAST | 80 | |
Regioni | 205 – 266 | DisorderedSequence analysisAdd BLAST | 62 | |
Regioni | 514 – 534 | DisorderedSequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 16 | Acidic residuesSequence analysisAdd BLAST | 16 | |
Compositional biasi | 114 – 142 | Polar residuesSequence analysisAdd BLAST | 29 | |
Compositional biasi | 205 – 234 | Polar residuesSequence analysisAdd BLAST | 30 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161054 |
HOGENOMi | CLU_010097_3_2_1 |
OMAi | MEHKTRC |
OrthoDBi | 105829at2759 |
TreeFami | TF331707 |
Family and domain databases
InterProi | View protein in InterPro IPR025243, DUF4195 IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF13836, DUF4195, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 6 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
Q505F4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEQPFTVDDE DEQDPEPQPR SGEPIQVLDD DAAEDAELIF VGVEKVKEDA
60 70 80 90 100
ELIFVGVTSA SQPANSNILN RVTPGSRLKR KHDRLRATTT QRLQPSRPAA
110 120 130 140 150
PTSEAVVVLP ASPAESRSTD SPIAIEPLSE SDYRSSSPQV VPSSSSKCCS
160 170 180 190 200
PLVTLSSSEN SPVKAALSGG DLNENLYVSK CHFSINPQRP DHSIEIVEPL
210 220 230 240 250
SSALPPSGTF HTSNMQQRTP SFDAPNSLSR LVNGAPPSED SAHPRQDSGL
260 270 280 290 300
AEADFSSPAS QETFDPKKGS LTLLLSDFYY GQYKGDGKPE QKTHTTFKCP
310 320 330 340 350
SCLKALKNVK FMNHTKHHLE LERQGSEDAW ESHTTCLRCH RQFDSPFQLE
360 370 380 390 400
CHIDRVHTSP DPSVVCKICE LSFETDQVLL QHMKDNHKPG EMPYVCQVCK
410 420 430 440 450
YRSSGFADVE THFTKCHVNT KNLLCPFCLK IFKTGMPYMC HYRGHWERSG
460 470 480 490 500
HQCSKCRLQF LTFKEKMEHK TQCHQMFKKP KQLEGLPPET KVVIQVSLQP
510 520 530
VESESVKVAS ITVSTTDWEP SNPRPQGRLS QKPH
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketA0A1W2P8C5 | A0A1W2P8C5_MOUSE | Zinc finger protein 280B | Zfp280b | 33 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC094574 mRNA Translation: AAH94574.1 BC117874 mRNA Translation: AAI17875.1 |
RefSeqi | NP_803426.2, NM_177475.3 XP_006514005.1, XM_006513942.2 XP_006514006.1, XM_006513943.2 |
Genome annotation databases
Ensembli | ENSMUST00000061617.7; ENSMUSP00000056340.7; ENSMUSG00000049764.9 |
GeneIDi | 64453 |
KEGGi | mmu:64453 |
UCSCi | uc007ftw.2, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC094574 mRNA Translation: AAH94574.1 BC117874 mRNA Translation: AAI17875.1 |
RefSeqi | NP_803426.2, NM_177475.3 XP_006514005.1, XM_006513942.2 XP_006514006.1, XM_006513943.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000056340 |
Proteomic databases
ProteomicsDBi | 335194 |
Protocols and materials databases
Antibodypediai | 73538, 104 antibodies from 21 providers |
DNASUi | 64453 |
Genome annotation databases
Ensembli | ENSMUST00000061617.7; ENSMUSP00000056340.7; ENSMUSG00000049764.9 |
GeneIDi | 64453 |
KEGGi | mmu:64453 |
UCSCi | uc007ftw.2, mouse |
Organism-specific databases
CTDi | 64453 |
MGIi | MGI:1927865, Zfp280b |
VEuPathDBi | HostDB:ENSMUSG00000049764 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000161054 |
HOGENOMi | CLU_010097_3_2_1 |
OMAi | MEHKTRC |
OrthoDBi | 105829at2759 |
TreeFami | TF331707 |
Miscellaneous databases
BioGRID-ORCSi | 64453, 1 hit in 72 CRISPR screens |
ChiTaRSi | Zfp280b, mouse |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000049764, Expressed in zygote and 243 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR025243, DUF4195 IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF13836, DUF4195, 1 hit |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 6 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 4 hits PS50157, ZINC_FINGER_C2H2_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q505F4_MOUSE | |
Accessioni | Q505F4Primary (citable) accession number: Q505F4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 7, 2005 |
Last sequence update: | June 7, 2005 | |
Last modified: | May 25, 2022 | |
This is version 113 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |