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Protein
Submitted name:

-Ha-ras Harvey rat sarcoma viral oncogene homolog b

Gene

hrasb

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-DRE-1169092 Activation of RAS in B cells
R-DRE-1250347 SHC1 events in ERBB4 signaling
R-DRE-1433557 Signaling by SCF-KIT
R-DRE-179812 GRB2 events in EGFR signaling
R-DRE-180336 SHC1 events in EGFR signaling
R-DRE-186763 Downstream signal transduction
R-DRE-1963640 GRB2 events in ERBB2 signaling
R-DRE-210993 Tie2 Signaling
R-DRE-2179392 EGFR Transactivation by Gastrin
R-DRE-2424491 DAP12 signaling
R-DRE-2871796 FCERI mediated MAPK activation
R-DRE-375165 NCAM signaling for neurite out-growth
R-DRE-3928662 EPHB-mediated forward signaling
R-DRE-442982 Ras activation upon Ca2+ influx through NMDA receptor
R-DRE-5218921 VEGFR2 mediated cell proliferation
R-DRE-5621575 CD209 (DC-SIGN) signaling
R-DRE-5654688 SHC-mediated cascade:FGFR1
R-DRE-5654693 FRS-mediated FGFR1 signaling
R-DRE-5654699 SHC-mediated cascade:FGFR2
R-DRE-5654700 FRS-mediated FGFR2 signaling
R-DRE-5654704 SHC-mediated cascade:FGFR3
R-DRE-5654706 FRS-mediated FGFR3 signaling
R-DRE-5654712 FRS-mediated FGFR4 signaling
R-DRE-5654719 SHC-mediated cascade:FGFR4
R-DRE-5658442 Regulation of RAS by GAPs
R-DRE-5673000 RAF activation
R-DRE-5673001 RAF/MAP kinase cascade
R-DRE-5674135 MAP2K and MAPK activation
R-DRE-5675221 Negative regulation of MAPK pathway
R-DRE-8849471 PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
R-DRE-8851805 MET activates RAS signaling

Names & Taxonomyi

Protein namesi
Submitted name:
-Ha-ras Harvey rat sarcoma viral oncogene homolog bImported
Submitted name:
-Ha-ras Harvey rat sarcoma viral oncogene homolog, likeImported
Gene namesi
Name:hrasbImported
Synonyms:hraslImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 7

Organism-specific databases

ZFINiZDB-GENE-050522-466 hrasb

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSDARG00000005651

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000016622

Family & Domainsi

Phylogenomic databases

eggNOGiKOG0395 Eukaryota
COG1100 LUCA
GeneTreeiENSGT00860000133672
HOGENOMiHOG000233973
HOVERGENiHBG009351
KOiK02833
OMAiCMNCRCV
OrthoDBiEOG091G0UAU
TreeFamiTF312796

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR005225 Small_GTP-bd_dom
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type
PANTHERiPTHR24070 PTHR24070, 1 hit
PfamiView protein in Pfam
PF00071 Ras, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR00231 small_GTP, 1 hit
PROSITEiView protein in PROSITE
PS51421 RAS, 1 hit

Sequencei

Sequence statusi: Complete.

Q503B6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET
60 70 80 90 100
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI
110 120 130 140 150
KRVKDSDDVP MVLVGNKCDL PARTVDTRQA QELARSYGIP YIETSAKTRQ
160 170 180
GVEDAFYTLV REIRQHKLRK LNPPDDNGQD CMNCRCVVS
Length:189
Mass (Da):21,481
Last modified:June 7, 2005 - v1
Checksum:i0FDBF83D95516686
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX088691 Genomic DNA No translation available.
BC095393 mRNA Translation: AAH95393.1
RefSeqiNP_001018465.1, NM_001020629.1
UniGeneiDr.8916

Genome annotation databases

EnsembliENSDART00000015040; ENSDARP00000016622; ENSDARG00000005651
ENSDART00000193674; ENSDARP00000155885; ENSDARG00000005651
GeneIDi553656
KEGGidre:553656

Similar proteinsi

Entry informationi

Entry nameiQ503B6_DANRE
AccessioniPrimary (citable) accession number: Q503B6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: June 20, 2018
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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