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Protein

MORN repeat-containing protein 2

Gene

MORN2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Might have a role in spermatogenesis.By similarity

GO - Biological processi

Keywordsi

Biological processDifferentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
MORN repeat-containing protein 2Imported
Alternative name(s):
MORN motif protein in testis1 Publication
Gene namesi
Name:MORN2Imported
Synonyms:MOPT1 Publication
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000188010.12
HGNCiHGNC:30166 MORN2
neXtProtiNX_Q502X0

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasmic vesicle, Nucleus

Pathology & Biotechi

Organism-specific databases

DisGeNETi729967
OpenTargetsiENSG00000188010
PharmGKBiPA142671343

Polymorphism and mutation databases

BioMutaiMORN2
DMDMi110810457

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002474571 – 79MORN repeat-containing protein 2Add BLAST79

Proteomic databases

MaxQBiQ502X0
PaxDbiQ502X0
PeptideAtlasiQ502X0
PRIDEiQ502X0
ProteomicsDBi62399

PTM databases

iPTMnetiQ502X0
PhosphoSitePlusiQ502X0

Expressioni

Gene expression databases

BgeeiENSG00000188010 Expressed in 186 organ(s), highest expression level in testis
CleanExiHS_MORN2
ExpressionAtlasiQ502X0 baseline and differential
GenevisibleiQ502X0 HS

Organism-specific databases

HPAiHPA057815

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GORASP2Q9H8Y83EBI-725982,EBI-739467

Protein-protein interaction databases

BioGridi610358, 4 interactors
IntActiQ502X0, 2 interactors
STRINGi9606.ENSP00000344551

Structurei

3D structure databases

ProteinModelPortaliQ502X0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati15 – 36MORN 1Sequence analysisAdd BLAST22
Repeati38 – 55MORN 2Sequence analysisAdd BLAST18

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410J2DM Eukaryota
ENOG4111Z4K LUCA
GeneTreeiENSGT00390000006619
HOGENOMiHOG000000688
HOVERGENiHBG081981
InParanoidiQ502X0
OMAiGTFHFTA
OrthoDBiEOG091G0WNQ
PhylomeDBiQ502X0
TreeFamiTF352715

Family and domain databases

InterProiView protein in InterPro
IPR003409 MORN
PfamiView protein in Pfam
PF02493 MORN, 2 hits
SMARTiView protein in SMART
SM00698 MORN, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q502X0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNGFGRLEHF SGAVYEGQFK DNMFHGLGTY TFPNGAKYTG NFNENRVEGE
60 70
GEYTDIQGLE WSGNFHFTAA PDLKLKLHM
Length:79
Mass (Da):8,939
Last modified:July 25, 2006 - v2
Checksum:i93D0A55736E956FA
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F8WEM8F8WEM8_HUMAN
MORN repeat-containing protein 2
MORN2
68Annotation score:
B8ZZN7B8ZZN7_HUMAN
MORN repeat-containing protein 2
MORN2
57Annotation score:
B8ZZ40B8ZZ40_HUMAN
MORN repeat-containing protein 2
MORN2
46Annotation score:
A0A2R8YE86A0A2R8YE86_HUMAN
MORN repeat-containing protein 2
MORN2
151Annotation score:

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_02710648E → K1 PublicationCorresponds to variant dbSNP:rs3099950Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY367766 mRNA Translation: AAQ73170.1
BC095472 mRNA Translation: AAH95472.1
BC102032 mRNA Translation: AAI02033.1
BC102034 mRNA Translation: AAI02035.1
BC102035 mRNA Translation: AAI02036.1
CCDSiCCDS46262.1
RefSeqiNP_001138922.1, NM_001145450.1
UniGeneiHs.729207

Genome annotation databases

EnsembliENST00000340556; ENSP00000344551; ENSG00000188010
ENST00000409665; ENSP00000386874; ENSG00000188010
ENST00000410014; ENSP00000386563; ENSG00000188010
GeneIDi729967
KEGGihsa:729967
UCSCiuc010fak.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY367766 mRNA Translation: AAQ73170.1
BC095472 mRNA Translation: AAH95472.1
BC102032 mRNA Translation: AAI02033.1
BC102034 mRNA Translation: AAI02035.1
BC102035 mRNA Translation: AAI02036.1
CCDSiCCDS46262.1
RefSeqiNP_001138922.1, NM_001145450.1
UniGeneiHs.729207

3D structure databases

ProteinModelPortaliQ502X0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi610358, 4 interactors
IntActiQ502X0, 2 interactors
STRINGi9606.ENSP00000344551

PTM databases

iPTMnetiQ502X0
PhosphoSitePlusiQ502X0

Polymorphism and mutation databases

BioMutaiMORN2
DMDMi110810457

Proteomic databases

MaxQBiQ502X0
PaxDbiQ502X0
PeptideAtlasiQ502X0
PRIDEiQ502X0
ProteomicsDBi62399

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000340556; ENSP00000344551; ENSG00000188010
ENST00000409665; ENSP00000386874; ENSG00000188010
ENST00000410014; ENSP00000386563; ENSG00000188010
GeneIDi729967
KEGGihsa:729967
UCSCiuc010fak.3 human

Organism-specific databases

CTDi729967
DisGeNETi729967
EuPathDBiHostDB:ENSG00000188010.12
GeneCardsiMORN2
HGNCiHGNC:30166 MORN2
HPAiHPA057815
neXtProtiNX_Q502X0
OpenTargetsiENSG00000188010
PharmGKBiPA142671343
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410J2DM Eukaryota
ENOG4111Z4K LUCA
GeneTreeiENSGT00390000006619
HOGENOMiHOG000000688
HOVERGENiHBG081981
InParanoidiQ502X0
OMAiGTFHFTA
OrthoDBiEOG091G0WNQ
PhylomeDBiQ502X0
TreeFamiTF352715

Miscellaneous databases

ChiTaRSiMORN2 human
GenomeRNAii729967
PROiPR:Q502X0

Gene expression databases

BgeeiENSG00000188010 Expressed in 186 organ(s), highest expression level in testis
CleanExiHS_MORN2
ExpressionAtlasiQ502X0 baseline and differential
GenevisibleiQ502X0 HS

Family and domain databases

InterProiView protein in InterPro
IPR003409 MORN
PfamiView protein in Pfam
PF02493 MORN, 2 hits
SMARTiView protein in SMART
SM00698 MORN, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiMORN2_HUMAN
AccessioniPrimary (citable) accession number: Q502X0
Secondary accession number(s): Q6UL00
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: July 25, 2006
Last modified: November 7, 2018
This is version 95 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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Main funding by: National Institutes of Health

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