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UniProtKB - Q501D2 (IQD30_ARATH)
Protein
Protein IQ-DOMAIN 30
Gene
IQD30
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
May be involved in cooperative interactions with calmodulins or calmodulin-like proteins (By similarity).
Recruits calmodulin proteins to microtubules, thus being a potential scaffold in cellular signaling and trafficking (By similarity).
May associate with nucleic acids and regulate gene expression at the transcriptional or post-transcriptional level (By similarity).
By similarityGO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
Keywordsi
Molecular function | Calmodulin-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein IQ-DOMAIN 301 PublicationShort name: AtIQD301 Publication |
Gene namesi | Name:IQD301 Publication Ordered Locus Names:At1g18840Imported ORF Names:F6A14.7Imported |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT1G18840 |
TAIRi | locus:2034929, AT1G18840 |
Subcellular locationi
Cytoskeleton
- cytoskeleton 1 Publication
Nucleus
- Nucleus envelope 1 Publication
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Nucleus
- nuclear envelope Source: UniProtKB-SubCell
Vacuole
- plant-type vacuole Source: TAIR
Keywords - Cellular componenti
Cytoplasm, Cytoskeleton, NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000453135 | 1 – 572 | Protein IQ-DOMAIN 30Add BLAST | 572 |
Proteomic databases
PaxDbi | Q501D2 |
PRIDEi | Q501D2 |
ProteomicsDBi | 174847 |
Interactioni
Subunit structurei
Binds to multiple calmodulin (CaM) in the presence of Ca2+ and CaM-like proteins.
By similarityGO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
Protein-protein interaction databases
STRINGi | 3702.AT1G18840.1 |
Structurei
3D structure databases
AlphaFoldDBi | Q501D2 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 108 – 136 | IQ 1PROSITE-ProRule annotationAdd BLAST | 29 | |
Domaini | 137 – 154 | IQ 2PROSITE-ProRule annotationAdd BLAST | 18 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 75 – 96 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 159 – 178 | Calmodulin-binding1 PublicationAdd BLAST | 20 | |
Regioni | 282 – 332 | DisorderedSequence analysisAdd BLAST | 51 | |
Regioni | 399 – 572 | DisorderedSequence analysisAdd BLAST | 174 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 80 – 96 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 290 – 307 | Polar residuesSequence analysisAdd BLAST | 18 | |
Compositional biasi | 399 – 421 | Polar residuesSequence analysisAdd BLAST | 23 | |
Compositional biasi | 428 – 453 | Basic and acidic residuesSequence analysisAdd BLAST | 26 | |
Compositional biasi | 454 – 489 | Polar residuesSequence analysisAdd BLAST | 36 | |
Compositional biasi | 497 – 561 | Polar residuesSequence analysisAdd BLAST | 65 |
Sequence similaritiesi
Belongs to the IQD family.Curated
Keywords - Domaini
RepeatPhylogenomic databases
eggNOGi | ENOG502QTUQ, Eukaryota |
HOGENOMi | CLU_026881_0_0_1 |
InParanoidi | Q501D2 |
OMAi | VPHIEVE |
OrthoDBi | 533192at2759 |
PhylomeDBi | Q501D2 |
Family and domain databases
InterProi | View protein in InterPro IPR025064, DUF4005 IPR000048, IQ_motif_EF-hand-BS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF13178, DUF4005, 1 hit PF00612, IQ, 2 hits |
SMARTi | View protein in SMART SM00015, IQ, 2 hits |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
i Sequence
Sequence statusi: Complete.
Q501D2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKPARWLKS VLLGKKPSKS SGSKDKERIV NGKEVVVISK IEESDVVSDL
60 70 80 90 100
SSIGNAAVYT SGIVETQNLK HEDVSDDEIQ VSEVQPTDSQ DVASVPDDSL
110 120 130 140 150
SESEKIQQEI AAVTVQAAYR GYLARRAFKI LKGIIRLQAL IRGHMVRRQA
160 170 180 190 200
VSTLCCVMGI VRLQALARGR EIRHSDIGVE VQRKCHLHHQ PLENKANSVV
210 220 230 240 250
DTHSYLGINK LTGNAFAQKL LASSPNVLPL SLDNDSSNSI WLENWSASCF
260 270 280 290 300
WKPVPQPKKA SLRKSQKKFA SNPQIVEAEF ARPKKSVRKV PSSNLDNSSV
310 320 330 340 350
AQTSSELEKP KRSFRKVSTS QSVEPLPSMD NPQVDLEKVK RGLRKVHNPV
360 370 380 390 400
VENSIQPQLV PQIAVEKPNG SLEESVNAFD EEKEDEVAET VVQQPEELIQ
410 420 430 440 450
THTPLGTNES LDSTLVNQIE ESEENVMAEE KEDVKEERTP KQNHKENSAG
460 470 480 490 500
KENQKSGKKA SSVTATQTAE FQESGNGNQT SSPGIPSYMQ ATKSAKAKLR
510 520 530 540 550
LQGSSSPRQL GTTEKASRRY SLPSSGNSAK ITSHSPKTRV SNSSGKSGNK
560 570
TEKTLLSSRE GNGKATPVEW KR
Sequence cautioni
The sequence AAF27097 differs from that shown. Reason: Erroneous gene model prediction.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 183 | R → G in BAH20070 (PubMed:19423640).Curated | 1 | |
Sequence conflicti | 564 | K → R in BAH20070 (PubMed:19423640).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011809 Genomic DNA Translation: AAF27097.1 Sequence problems. CP002684 Genomic DNA Translation: AEE29769.1 CP002684 Genomic DNA Translation: AEE29770.1 CP002684 Genomic DNA Translation: ANM60334.1 AK317400 mRNA Translation: BAH20070.1 BT022035 mRNA Translation: AAY25447.1 AY702666 mRNA Translation: AAW22636.1 |
PIRi | C86322 |
RefSeqi | NP_001031067.1, NM_001035990.2 NP_001322630.1, NM_001332375.1 NP_173318.2, NM_101741.4 |
Genome annotation databases
EnsemblPlantsi | AT1G18840.1; AT1G18840.1; AT1G18840 AT1G18840.2; AT1G18840.2; AT1G18840 AT1G18840.3; AT1G18840.3; AT1G18840 |
GeneIDi | 838465 |
Gramenei | AT1G18840.1; AT1G18840.1; AT1G18840 AT1G18840.2; AT1G18840.2; AT1G18840 AT1G18840.3; AT1G18840.3; AT1G18840 |
KEGGi | ath:AT1G18840 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC011809 Genomic DNA Translation: AAF27097.1 Sequence problems. CP002684 Genomic DNA Translation: AEE29769.1 CP002684 Genomic DNA Translation: AEE29770.1 CP002684 Genomic DNA Translation: ANM60334.1 AK317400 mRNA Translation: BAH20070.1 BT022035 mRNA Translation: AAY25447.1 AY702666 mRNA Translation: AAW22636.1 |
PIRi | C86322 |
RefSeqi | NP_001031067.1, NM_001035990.2 NP_001322630.1, NM_001332375.1 NP_173318.2, NM_101741.4 |
3D structure databases
AlphaFoldDBi | Q501D2 |
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 3702.AT1G18840.1 |
Proteomic databases
PaxDbi | Q501D2 |
PRIDEi | Q501D2 |
ProteomicsDBi | 174847 |
Genome annotation databases
EnsemblPlantsi | AT1G18840.1; AT1G18840.1; AT1G18840 AT1G18840.2; AT1G18840.2; AT1G18840 AT1G18840.3; AT1G18840.3; AT1G18840 |
GeneIDi | 838465 |
Gramenei | AT1G18840.1; AT1G18840.1; AT1G18840 AT1G18840.2; AT1G18840.2; AT1G18840 AT1G18840.3; AT1G18840.3; AT1G18840 |
KEGGi | ath:AT1G18840 |
Organism-specific databases
Araporti | AT1G18840 |
TAIRi | locus:2034929, AT1G18840 |
Phylogenomic databases
eggNOGi | ENOG502QTUQ, Eukaryota |
HOGENOMi | CLU_026881_0_0_1 |
InParanoidi | Q501D2 |
OMAi | VPHIEVE |
OrthoDBi | 533192at2759 |
PhylomeDBi | Q501D2 |
Gene expression databases
ExpressionAtlasi | Q501D2, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR025064, DUF4005 IPR000048, IQ_motif_EF-hand-BS IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF13178, DUF4005, 1 hit PF00612, IQ, 2 hits |
SMARTi | View protein in SMART SM00015, IQ, 2 hits |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS50096, IQ, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | IQD30_ARATH | |
Accessioni | Q501D2Primary (citable) accession number: Q501D2 Secondary accession number(s): B9DH53, Q2NND8, Q9M9V3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 2, 2021 |
Last sequence update: | June 7, 2005 | |
Last modified: | May 25, 2022 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families