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UniProtKB - Q4ZG85 (Q4ZG85_HUMAN)

Entry version 63 (07 Oct 2020)
Sequence version 1 (07 Jun 2005)
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Protein
Submitted name:

Uncharacterized protein CRIM1

Gene

CRIM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized protein CRIM1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CRIM1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...PeptideAtlasi		Q4ZG85

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini223 – 280VWFCInterPro annotationAdd BLAST58
Domaini290 – 346VWFCInterPro annotationAdd BLAST57
Domaini358 – 387Antistasin-likeInterPro annotationAdd BLAST30
Domaini394 – 421Antistasin-likeInterPro annotationAdd BLAST28
Domaini428 – 453Antistasin-likeInterPro annotationAdd BLAST26
Domaini456 – 481Antistasin-likeInterPro annotationAdd BLAST26
Domaini495 – 552VWFCInterPro annotationAdd BLAST58
Domaini566 – 624VWFCInterPro annotationAdd BLAST59
Domaini640 – 698VWFCInterPro annotationAdd BLAST59
Domaini706 – 763VWFCInterPro annotationAdd BLAST58

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004094, Antistasin-like
IPR011061, Hirudin/antistatin
IPR001007, VWF_dom

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02822, Antistasin, 4 hits
PF00093, VWC, 6 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00214, VWC, 6 hits
SM00215, VWC_out, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57262, SSF57262, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51252, ANTISTASIN, 4 hits
PS01208, VWFC_1, 3 hits
PS50184, VWFC_2, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q4ZG85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
ENWTDDQLLG FKPCNENLIA GCNIINGKCE CNTIRTCSNP FEFPSQDMCL 
        60         70         80         90        100
SALKRIEEEK PDCSKARCEV QFSPRCPEDS VLIEGYAPPG ECCPLPSRCV 
       110        120        130        140        150
CNPAGCLRKV CQPGNLNILV SKASGKPGEC CDLYECKPVF GVDCRTVECP 
       160        170        180        190        200
PVQQTACPPD SYETQVRLTA DGCCTLPTRC ECLSGLCGFP VCEVGSTPRI 
       210        220        230        240        250
VSRGDGTPGK CCDVFECVND TKPACVFNNV EYYDGDMFRM DNCRFCRCQG 
       260        270        280        290        300
GVAICFTAQC GEINCERYYV PEGECCPVCE DPVYPFNNPA GCYANGLILA 
       310        320        330        340        350
HGDRWREDDC TFCQCVNGER HCVATVCGQT CTNPVKVPGE CCPVCEEPTI 
       360        370        380        390        400
ITVDPPACGE LSNCTLTGKD CINGFKRDHN GCRTCQCINT EELCSERKQG 
       410        420        430        440        450
CTLNCPFGFL TDAQNCEICE CRPRPKKCRP IICDKYCPLG LLKNKHGCDI 
       460        470        480        490        500
CRCKKCPELS CSKICPLGFQ QDSHGCLICK CREASASAGP PILSGTCLTV 
       510        520        530        540        550
DGHHHKNEES WHDGCRECYC LNGREMCALI TCPVPACGNP TIHPGQCCPS 
       560        570        580        590        600
CADDFVVQKP ELSTPSICHA PGGEYFVEGE TWNIDSCTQC TCHSGRVLCE 
       610        620        630        640        650
TEVCPPLLCQ NPSRTQDSCC PQCTDQPFRP SLSRNNSVPN YCKNDEGDIF 
       660        670        680        690        700
LAAESWKPDV CTSCICIDSV ISCFSESCPS VSCERPVLRK GQCCPYCIED 
       710        720        730        740        750
TIPKKVVCHF SGKAYADEER WDLDSCTHCY CLQGQTLCST VSCPPLPCVE 
       760 
PINVEGSCCP MCP
Length:763
Mass (Da):83,432
Last modified:June 7, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEC84DC48D16AED18
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei763Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AC007378 Genomic DNA Translation: AAX88862.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC007378 Genomic DNA Translation: AAX88862.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PeptideAtlasiQ4ZG85

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		CRIM1, human

Family and domain databases

InterProiView protein in InterPro
IPR004094, Antistasin-like
IPR011061, Hirudin/antistatin
IPR001007, VWF_dom
PfamiView protein in Pfam
PF02822, Antistasin, 4 hits
PF00093, VWC, 6 hits
SMARTiView protein in SMART
SM00214, VWC, 6 hits
SM00215, VWC_out, 4 hits
SUPFAMiSSF57262, SSF57262, 3 hits
PROSITEiView protein in PROSITE
PS51252, ANTISTASIN, 4 hits
PS01208, VWFC_1, 3 hits
PS50184, VWFC_2, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4ZG85_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4ZG85
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 7, 2005
Last sequence update: June 7, 2005
Last modified: October 7, 2020
This is version 63 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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