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UniProtKB - Q4Z1L3 (ACT1_PLABA)
Protein
Actin-1
Gene
PB000323.01.0
Organism
Plasmodium berghei (strain Anka)
Status
Functioni
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
Keywordsi
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Actin-1Alternative name(s): Actin I |
Gene namesi | ORF Names:PB000323.01.0 |
Organismi | Plasmodium berghei (strain Anka) |
Taxonomic identifieri | 5823 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Vinckeia) › |
Organism-specific databases
VEuPathDBi | PlasmoDB:PBANKA_1459300 |
Subcellular locationi
Cytoskeleton
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000233388 | 1 – 376 | Actin-1Add BLAST | 376 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
AlphaFoldDBi | Q4Z1L3 |
SMRi | Q4Z1L3 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the actin family.Curated
Phylogenomic databases
eggNOGi | KOG0676, Eukaryota |
InParanoidi | Q4Z1L3 |
OMAi | FHTTAER |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR004001, Actin_CS IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
PRINTSi | PR00190, ACTIN |
SMARTi | View protein in SMART SM00268, ACTIN, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
PROSITEi | View protein in PROSITE PS00406, ACTINS_1, 1 hit PS00432, ACTINS_2, 1 hit PS01132, ACTINS_ACT_LIKE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4Z1L3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGDEEVQALV IDNGSGNVKA GVAGDDAPRS VFPSIVGRPK NPGIMVGMEE
60 70 80 90 100
KDAFVGDEAQ TKRGILTLKY PIEHGIVTNW DDMEKIWHHT FYNELRAAPE
110 120 130 140 150
EHPVLLTEAP LNPKGNRERM TQIMFESFNV PAMYVAIQAV LSLYSSGRTT
160 170 180 190 200
GIVLDSGDGV SHTVPIYEGY ALPHAIMRLD LAGRDLTEYL MKILHERGYG
210 220 230 240 250
FSTSAEKEIV RDIKEKLCYI ALNFDEEMKT SEQSSDIEKS YELPDGNIIT
260 270 280 290 300
VGNERFRCPE ALFQPSFLGK EAAGIHTTTF NSIKKCDVDI RKDLYGNIVL
310 320 330 340 350
SGGTTMYEGI GERLTRDITT LAPSTMKIKV VAPPERKYSV WIGGSILSSL
360 370
STFQQMWITK EEYDESGPSI VHRKCF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CAAI01001113 Genomic DNA Translation: CAH95825.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CAAI01001113 Genomic DNA Translation: CAH95825.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4CBW | X-ray | 2.50 | A | 62-333 | [»] | |
A | 335-376 | [»] | ||||
AlphaFoldDBi | Q4Z1L3 | |||||
SMRi | Q4Z1L3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 5821.PBANKA_145930 |
Protocols and materials databases
ABCDi | Q4Z1L3, 1 sequenced antibody |
Organism-specific databases
VEuPathDBi | PlasmoDB:PBANKA_1459300 |
Phylogenomic databases
eggNOGi | KOG0676, Eukaryota |
InParanoidi | Q4Z1L3 |
OMAi | FHTTAER |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR004001, Actin_CS IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
PRINTSi | PR00190, ACTIN |
SMARTi | View protein in SMART SM00268, ACTIN, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
PROSITEi | View protein in PROSITE PS00406, ACTINS_1, 1 hit PS00432, ACTINS_2, 1 hit PS01132, ACTINS_ACT_LIKE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ACT1_PLABA | |
Accessioni | Q4Z1L3Primary (citable) accession number: Q4Z1L3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 2, 2006 |
Last sequence update: | August 30, 2017 | |
Last modified: | May 25, 2022 | |
This is version 74 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families