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UniProtKB - Q4YU79 (ACT2_PLABA)
Protein
Actin-2
Gene
PB001050.02.0
Organism
Plasmodium berghei (strain Anka)
Status
Functioni
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
Keywordsi
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Actin-2Alternative name(s): Actin II |
Gene namesi | ORF Names:PB001050.02.0 |
Organismi | Plasmodium berghei (strain Anka) |
Taxonomic identifieri | 5823 [NCBI] |
Taxonomic lineagei | Eukaryota › Sar › Alveolata › Apicomplexa › Aconoidasida › Haemosporida › Plasmodiidae › Plasmodium › Plasmodium (Vinckeia) › |
Organism-specific databases
VEuPathDBi | PlasmoDB:PBANKA_1030100 |
Subcellular locationi
Cytoskeleton
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000233391 | 1 – 376 | Actin-2Add BLAST | 376 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q4YU79 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Sequence similaritiesi
Belongs to the actin family.Curated
Phylogenomic databases
eggNOGi | KOG0676, Eukaryota |
HOGENOMi | CLU_027965_0_2_1 |
InParanoidi | Q4YU79 |
OMAi | PNIMVGM |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR004001, Actin_CS IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
PRINTSi | PR00190, ACTIN |
SMARTi | View protein in SMART SM00268, ACTIN, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
PROSITEi | View protein in PROSITE PS00406, ACTINS_1, 1 hit PS00432, ACTINS_2, 1 hit PS01132, ACTINS_ACT_LIKE, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4YU79-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPEESIALVV DNGSGMVKSG LAGDDAPKCV FPSIIGIPKM PNIMVGMEQK
60 70 80 90 100
ECYVGDEAQN KRGILTLKYP IEHGIVTNWD DMEKIWRHTF FNELRVSPEE
110 120 130 140 150
HPVLLTEAPL NPKTNREKMT QIMFESFDVP AMYVSIQAIL SLYASGRTTG
160 170 180 190 200
IVLDSGDGVT HTVPIYEGYV LPHAINRTDM AGRDLTYYMM KLFTERGYTF
210 220 230 240 250
TTTAEREIVR DIKEKLCYIA LDYDEELKKS EERTEEVEEM YELPDGNLIT
260 270 280 290 300
VGSERFRCPE ALFNPSLIGR ECPGLHITAY QSIMKCDIDI RKELYNNIVL
310 320 330 340 350
SGGTTMYNYI GERLTNEMTS LAPPSMKIKV IAPPERKYSV WIGGSILSSL
360 370
STFQKMWITK EEYDESGPSI VHRKCF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CAAI01002399 Genomic DNA Translation: CAH98428.1 |
RefSeqi | XP_680164.1, XM_675072.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CAAI01002399 Genomic DNA Translation: CAH98428.1 |
RefSeqi | XP_680164.1, XM_675072.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4CBX | X-ray | 2.20 | A | 1-376 | [»] | |
6I4M | X-ray | 1.87 | A | 1-376 | [»] | |
SMRi | Q4YU79 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 5821.PBANKA_103010 |
Organism-specific databases
VEuPathDBi | PlasmoDB:PBANKA_1030100 |
Phylogenomic databases
eggNOGi | KOG0676, Eukaryota |
HOGENOMi | CLU_027965_0_2_1 |
InParanoidi | Q4YU79 |
OMAi | PNIMVGM |
Family and domain databases
InterProi | View protein in InterPro IPR004000, Actin IPR020902, Actin/actin-like_CS IPR004001, Actin_CS IPR043129, ATPase_NBD |
PANTHERi | PTHR11937, PTHR11937, 1 hit |
Pfami | View protein in Pfam PF00022, Actin, 1 hit |
PRINTSi | PR00190, ACTIN |
SMARTi | View protein in SMART SM00268, ACTIN, 1 hit |
SUPFAMi | SSF53067, SSF53067, 2 hits |
PROSITEi | View protein in PROSITE PS00406, ACTINS_1, 1 hit PS00432, ACTINS_2, 1 hit PS01132, ACTINS_ACT_LIKE, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ACT2_PLABA | |
Accessioni | Q4YU79Primary (citable) accession number: Q4YU79 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 2, 2006 |
Last sequence update: | July 5, 2005 | |
Last modified: | September 29, 2021 | |
This is version 72 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
Miscellaneousi
Keywords - Technical termi
3D-structureDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families