UniProtKB - Q4X1Z9 (Q4X1Z9_ASPFU)
Protein
Tubulin-specific chaperone A
Gene
AFUA_2G08190
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Functioni
Caution
The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported
GO - Molecular functioni
- beta-tubulin binding Source: InterPro
- tubulin binding Source: GO_Central
GO - Biological processi
- post-chaperonin tubulin folding pathway Source: UniProtKB-UniRule
- protein folding Source: GO_Central
- tubulin complex assembly Source: GO_Central
Keywordsi
Molecular function | ChaperoneUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin-specific chaperone AUniRule annotation |
Gene namesi | ORF Names:AFUA_2G08190Imported |
Organismi | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)Imported |
Taxonomic identifieri | 330879 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Fumigati › |
Proteomesi |
|
Organism-specific databases
EuPathDBi | FungiDB:Afu2g08190 |
Subcellular locationi
Cytoskeleton
- cytoskeleton UniRule annotation
Cytoskeleton
- microtubule Source: UniProtKB-KW
- microtubule cytoskeleton Source: GO_Central
Cytosol
- cytosol Source: GO_Central
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotationInteractioni
Subunit structurei
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
UniRule annotationGO - Molecular functioni
- beta-tubulin binding Source: InterPro
- tubulin binding Source: GO_Central
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 28 – 48 | DisorderedSequence analysisAdd BLAST | 21 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 62 – 89 | Sequence analysisAdd BLAST | 28 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | ENOG502SH35, Eukaryota |
HOGENOMi | CLU_130569_0_0_1 |
InParanoidi | Q4X1Z9 |
OMAi | DENREYM |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4X1Z9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAPRSQLEIA TSSVERLVKE EASYHRELQQ QTERIQKLES QEPGEDENRE
60 70 80 90 100
YMLKQEMQRL ALEETKKVLP SLKQKIDEAV AKLESLLAEE GKKGPESNVE
110 120
QITAGKEAIA KAKTAKREIA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAHF01000001 Genomic DNA Translation: EAL93116.1 |
RefSeqi | XP_755154.1, XM_750061.1 |
Genome annotation databases
EnsemblFungii | EAL93116; EAL93116; AFUA_2G08190 |
GeneIDi | 3512808 |
KEGGi | afm:AFUA_2G08190 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAHF01000001 Genomic DNA Translation: EAL93116.1 |
RefSeqi | XP_755154.1, XM_750061.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
EnsemblFungii | EAL93116; EAL93116; AFUA_2G08190 |
GeneIDi | 3512808 |
KEGGi | afm:AFUA_2G08190 |
Organism-specific databases
EuPathDBi | FungiDB:Afu2g08190 |
Phylogenomic databases
eggNOGi | ENOG502SH35, Eukaryota |
HOGENOMi | CLU_130569_0_0_1 |
InParanoidi | Q4X1Z9 |
OMAi | DENREYM |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q4X1Z9_ASPFU | |
Accessioni | Q4X1Z9Primary (citable) accession number: Q4X1Z9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 5, 2005 |
Last sequence update: | July 5, 2005 | |
Last modified: | December 2, 2020 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |