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UniProtKB - Q4WLP9 (RBD2_ASPFU)
Protein
Rhomboid protein 2
Gene
rbd2
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Functioni
Probable serine protease.
By similaritySites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 138 | NucleophileBy similarity | 1 | |
Active sitei | 191 | By similarity | 1 |
GO - Molecular functioni
- serine-type endopeptidase activity Source: GO_Central
Keywordsi
Molecular function | Hydrolase, Protease, Serine protease |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:rbd2 ORF Names:AFUA_6G12750 |
Organismi | Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus) |
Taxonomic identifieri | 330879 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Fumigati › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | FungiDB:Afu6g12750 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus membrane By similarity; Multi-pass membrane protein By similarity
- cis-Golgi network membrane By similarity; Multi-pass membrane protein By similarity
Golgi apparatus
- Golgi membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 30 – 50 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 72 – 92 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 103 – 123 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 133 – 153 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 164 – 184 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 186 – 206 | HelicalSequence analysisAdd BLAST | 21 |
Keywords - Cellular componenti
Golgi apparatus, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000206183 | 1 – 272 | Rhomboid protein 2Add BLAST | 272 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the peptidase S54 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2632, Eukaryota |
HOGENOMi | CLU_084816_0_0_1 |
InParanoidi | Q4WLP9 |
OMAi | TFPLIHL |
OrthoDBi | 1588469at2759 |
Family and domain databases
Gene3Di | 1.20.1540.10, 1 hit |
InterProi | View protein in InterPro IPR022764, Peptidase_S54_rhomboid_dom IPR035952, Rhomboid-like_sf |
Pfami | View protein in Pfam PF01694, Rhomboid, 1 hit |
SUPFAMi | SSF144091, SSF144091, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4WLP9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAIPAALPPL PFNPTRVRSY MLRLPLFTRL VLLVILAFWL LELQTIWSVV
60 70 80 90 100
QWGSLTPNEI GIGSMYRLNT YPFIHVGFFH AFVNLLALTP LLERFEAEHG
110 120 130 140 150
TLTAVALFIG PLSTFPAGIY ILVEKFILRS NTAVVGASVW IFLLLGSEAI
160 170 180 190 200
KTFKSNPYFS LGTTKIPTWT SPLFACALVS IFVPNTSFLG HLSAIIIGYL
210 220 230 240 250
LGLGYLKVFV PPEKILRWIE GKLNLLGRLP HYVSVDQKTY GRYGVLPTAT
260 270
AAVGGERPTP LSYLGTNQRL GP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAHF01000006 Genomic DNA Translation: EAL89115.1 |
RefSeqi | XP_751153.1, XM_746060.1 |
Genome annotation databases
EnsemblFungii | EAL89115; EAL89115; AFUA_6G12750 |
GeneIDi | 3508460 |
KEGGi | afm:AFUA_6G12750 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AAHF01000006 Genomic DNA Translation: EAL89115.1 |
RefSeqi | XP_751153.1, XM_746060.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 746128.CADAFUBP00007676 |
Genome annotation databases
EnsemblFungii | EAL89115; EAL89115; AFUA_6G12750 |
GeneIDi | 3508460 |
KEGGi | afm:AFUA_6G12750 |
Organism-specific databases
VEuPathDBi | FungiDB:Afu6g12750 |
Phylogenomic databases
eggNOGi | KOG2632, Eukaryota |
HOGENOMi | CLU_084816_0_0_1 |
InParanoidi | Q4WLP9 |
OMAi | TFPLIHL |
OrthoDBi | 1588469at2759 |
Miscellaneous databases
PHI-basei | PHI:6861 |
Family and domain databases
Gene3Di | 1.20.1540.10, 1 hit |
InterProi | View protein in InterPro IPR022764, Peptidase_S54_rhomboid_dom IPR035952, Rhomboid-like_sf |
Pfami | View protein in Pfam PF01694, Rhomboid, 1 hit |
SUPFAMi | SSF144091, SSF144091, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | RBD2_ASPFU | |
Accessioni | Q4WLP9Primary (citable) accession number: Q4WLP9 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 6, 2005 |
Last sequence update: | July 5, 2005 | |
Last modified: | February 23, 2022 | |
This is version 96 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Peptidase families
Classification of peptidase families and list of entries - SIMILARITY comments
Index of protein domains and families