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UniProtKB - Q4WF53 (SIDD_ASPFU)

Entry version 95 (23 Feb 2022)
Sequence version 1 (05 Jul 2005)
Previous versions | rss
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Protein

Nonribosomal peptide synthase sidD

Gene

NRPS4

Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Nonribosomal peptide synthase; part of the siderophore biosynthetic pathway (PubMed:15953695, PubMed:17845073, PubMed:17464044).

Aspergillus fumigatus produces four types of siderophores, low-molecular-mass iron chelators, including excreted fusarinine C (FsC) and triacetylfusarinine C (TAFC) for iron uptake; and intacellular ferricrocin (FC) for hyphal and hydroxyferricrocin (HFC) for conidial iron distribution and storage. TAFC consists of three N2-acetyl-N5-anhydromevalonyl-N5-hydroxyornithine residues cyclically linked by ester bonds; FC is a cyclic hexapeptide with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)x3. The biosynthesis of all four siderophores depends on the hydroxylation of ornithine, catalyzed by the monooxygenase sidA (PubMed:15504822, PubMed:16113265).

Subsequently, the pathways for biosynthesis of extra- and intracellular siderophores split (PubMed:17845073).

For biosynthesis of extracellular siderophores, the transacylase sidF transfers anhydromevalonyl to N5-hydroxyornithine (PubMed:17845073).

The required anhydromevalonyl-CoA moiety is derived from mevalonate by CoA ligation and dehydration catalyzed by sidI and sidH respectively (PubMed:22106303).

The acetylation of N5-hydroxyornithine for FC biosynthesis involves the constitutively expressed sidL (PubMed:21622789).

FC is hydroxylated to HFC by an as yet uncharacterized enzyme during conidiation (PubMed:17845073).

Assembly of fusarinine C (FsC) and FC is catalyzed by two different nonribosomal peptide synthetases (NRPS), sidD and sidC respectively (PubMed:15953695, PubMed:17845073, PubMed:17464044).

Subsequently, sidG catalyzes N2-acetylation of FsC for forming TAFC (PubMed:17845073).

Both extra- and intracellular siderophores are crucial for growth during iron limitation and virulence (PubMed:16113265).

7 Publications

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: Siderophore biosynthesis

This protein is involved in Siderophore biosynthesis.1 Publication
View all proteins of this organism that are known to be involved in Siderophore biosynthesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionLigase
Biological processVirulence

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nonribosomal peptide synthase sidD1 Publication (EC:6.3.2.-1 Publication)
Short name:
NPRS sidD1 Publication
Alternative name(s):
Siderophore synthetase D1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:NRPS41 Publication
Synonyms:sidD1 Publication
ORF Names:AFUA_3G03420
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri330879 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Fumigati ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002530 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		FungiDB:Afu3g03420

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the 'Pathology and Biotech' section describes the in vivo effects caused by ablation of the gene (or one or more transcripts) coding for the protein described in the entry. This includes gene knockout and knockdown, provided experiments have been performed in the context of a whole organism or a specific tissue, and not at the single-cell level.<p><a href='/help/disruption_phenotype' target='_top'>More...</a></p>Disruption phenotypei

Prevents synthesis of TAFC and FsC without affecting FC production (PubMed:17845073).1 Publication

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004165451 – 2083Nonribosomal peptide synthase sidDAdd BLAST2083

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei801O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1
Modified residuei1594O-(pantetheine 4'-phosphoryl)serinePROSITE-ProRule annotation1

Keywords - PTMi

Phosphopantetheine, Phosphoprotein

Proteomic databases

PRoteomics IDEntifications database

More...PRIDEi		Q4WF53

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Expression is induced during iron starvation (PubMed:15953695, PubMed:17845073).2 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		746128.CADAFUBP00004398

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q4WF53

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini764 – 840Carrier 1PROSITE-ProRule annotationAdd BLAST77
Domaini1557 – 1633Carrier 2PROSITE-ProRule annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni251 – 650Adenylation 1Add BLAST400
Regioni876 – 1146Condensation 1Add BLAST271
Regioni1336 – 1421Adenylation 2Add BLAST86
Regioni1674 – 1946Condensation 2Add BLAST273

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

NRP synthetases are composed of discrete domains (adenylation (A), thiolation (T) or peptidyl carrier protein (PCP) and condensation (C) domains) which when grouped together are referred to as a single module. Each module is responsible for the recognition (via the A domain) and incorporation of a single amino acid into the growing peptide product. Thus, an NRP synthetase is generally composed of one or more modules and can terminate in a thioesterase domain (TE) that releases the newly synthesized peptide from the enzyme. Occasionally, epimerase (E) domains (responsible for l- to d- amino acid conversion) are present within the NRP synthetase. NRPS4 has the following architecture: A-T-C-A-C.2 Publications

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the NRP synthetase family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1178, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000022_60_2_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q4WF53

Identification of Orthologs from Complete Genome Data

More...OMAi		FNPYPLM

Database of Orthologous Groups

More...OrthoDBi		4243at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.1200.10, 2 hits
3.30.300.30, 2 hits
3.30.559.10, 2 hits
3.40.50.12780, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, ANL_N_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00501, AMP-binding, 1 hit
PF00668, Condensation, 2 hits
PF00550, PP-binding, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00823, PKS_PP, 2 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47336, SSF47336, 2 hits

TIGRFAMs; a protein family database

More...TIGRFAMsi		TIGR01733, AA-adenyl-dom, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS50075, CARRIER, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4WF53-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGSIQQDDVH NQIDHCNQSD DLPAARLNCN DVELFEVAGL ACDETSSPTG 
        60         70         80         90        100
MRDEMVLLSW LIALLRTREG GQIRYEWAYR YPEEEPVPRC LAMNEVVAGL 
       110        120        130        140        150
QSSVKETAAA VSRHISADVS SPPAPASLLL STSSLSQTSD EAKDEGLLHL 
       160        170        180        190        200
EIAFENGLCK IRPTWHSENM LPFTVTRYAR TLIDTVRLCI SNCDAAIQDC 
       210        220        230        240        250
LRPTAYDLDE IWRWNHNLPP TYNFCMHEII SDQAQKFPDK EAIASWDGSL 
       260        270        280        290        300
TYRQIDQYSS FVARSLIGMG VGLHDVLPVC FEKSRWTIVA VLAVMKAGAT 
       310        320        330        340        350
FVLMDPTLPL ARLQNMAQQV GAKMMVSSRG QYNLATEIIP NANVLVVEEN 
       360        370        380        390        400
TFSSLSAEQN GEPLPTVPSS ALMYMIFTSG STGTPKGVKI SHETYTSSAI 
       410        420        430        440        450
PRANAVGYTE DSRVLDFASY AFDVSIDSML LTLGNGGCLC IPSDEDRLND 
       460        470        480        490        500
INGVIRRMKV NYAGLTPSVA RILDADVISS LSGLGLGGEA VSARDVNLWG 
       510        520        530        540        550
QDTRIIIGYG PCECTIGCTV NSSAATGRDY ISIGPGNGAV IWIVDPNDHE 
       560        570        580        590        600
SLVPLGAVGE LLVEGPIVGQ GYLNDPEKTA AAFIEDPSWL VAGHEGYPGR 
       610        620        630        640        650
RGRLYKTGDL GRYDPDGSGG IVFVGRKDTQ VKLRGQRVEL GEIESQLRAR 
       660        670        680        690        700
LPSETTVIAE VIVPQGSGGQ PTLVAFVAAQ TTKGHDHTGL EAAELPDELR 
       710        720        730        740        750
RALSEADAEL AKVLPRYMVP TAYIPVNHIP TLISGKTDRK RLRQFGATVD 
       760        770        780        790        800
LRQLDQDATN TAARELSDLE RRLRQAWSQT LKLQACSIRL QDNFFALGGD 
       810        820        830        840        850
SLTAMKLVSV CRSQGLDLSV TSMFSNPTLS AMASVVRICD VDVQRTVPAF 
       860        870        880        890        900
SMITSDMNSA CVEAAEPCGV GPADIEDIYP CTPTQESLFT FSLKSVKPYV 
       910        920        930        940        950
AQRVLCIPSH IDLNAWRKAW EDVVAALPIL RTRVAQLQEP GLQQVVLKNS 
       960        970        980        990       1000
ISWTQASDLA EYLENDRTQK MNLGESLARY AIVEDSADGK RYMVWTIHHV 
      1010       1020       1030       1040       1050
LYDGWSEPII LKQVSDALQG QPVEVKAQMR DFVRFVRDSD DAAVQEFWRR 
      1060       1070       1080       1090       1100
ELKGAVGPQF PRLPSRDFMP TPDALVERQV SLDTSSGSPF TMATLIRGAW 
      1110       1120       1130       1140       1150
ALVASQYTGS DDIVFGETLT GRDIPLPGVE SIVGPLIATV PIRVRILRGS 
      1160       1170       1180       1190       1200
TVESYLQAVQ QSVLARTPYQ HLGMQNIRKV SQDAQHACET GTGLVIQPEP 
      1210       1220       1230       1240       1250
EYVGSELGVE RGDVVLEALH FNPYPLMLAC GIRKGGFRVC ASFDSSLIET 
      1260       1270       1280       1290       1300
RQMERMLAQL ETACWQLSQG LSRKVDEISC LPEAELNQIW QWNRSPPLSL 
      1310       1320       1330       1340       1350
DETTSRLRAN ASTKPGSSYP PAVVPWVCSP RNSSLLSPIG CVGELWLEGA 
      1360       1370       1380       1390       1400
LLSGDTVDSP AWLVAGSSTC AGRTGKVQAT GDMVQLREDG SLVFVGRKEN 
      1410       1420       1430       1440       1450
VVPVQGHAVD ITEIERHLAE HLPPTIRAAA TVVRSSSDQE LVMFIEQPAA 
      1460       1470       1480       1490       1500
EEACIELLSE KREIVCDAPD KAFQTTICAT IPGSLAAVLK KLDKYMRDSL 
      1510       1520       1530       1540       1550
PSYMAPSAYI VVEKLPNTMD DIDHNLLNQI ASQVTPQILN ELRDGLSNAW 
      1560       1570       1580       1590       1600
TKATAPNHLS ASESILRSAW AKVLRVDPEQ IDVDDNFFRR GGDSVLAMKL 
      1610       1620       1630       1640       1650
VSSLRAQGYS LSVADIFRHM RLSDAARVMK VDERSTEKIN SYQPFSMLRL 
      1660       1670       1680       1690       1700
PDVQQFLANI VRPQLGDQHW PIRDVLPVTD SQDMDIRATI QPPRTSIQYT 
      1710       1720       1730       1740       1750
MLYFDNSVDR ERLFRSCSDL VKTHEILRTV FISHESSFLQ VVLNELEIPV 
      1760       1770       1780       1790       1800
RAHKTDKQLD QYVASLFRED IESNFQLGCP FLRLFYVEGN NGESCLVIGL 
      1810       1820       1830       1840       1850
SHAQYDGVSL PRLLQDLDAL YTGTQLATFS PFSLYMAQTS EEAIQNKAAA 
      1860       1870       1880       1890       1900
YWRNLLSSSS LSTLDGPSSD PTDKAIFHTR PVNIHPLKEI TTANLLTAAW 
      1910       1920       1930       1940       1950
AMVLARRLQT PDVTFGSVTS GRTLDIPNAE NFMGPCYQLT PVRVPFHPDW 
      1960       1970       1980       1990       2000
TASDLLNFVQ TQSAESAAHD FLGFEKIAKL AGWASGRQGF DSIVHHQDWE 
      2010       2020       2030       2040       2050
DFDMMPFGGG SCRVDIANPH GDAAYPVKAV SFVKEGEIHV GVVCSERDVM 
      2060       2070       2080 
FVDEVLGELA AAVVELAGQS TEVLLDSKLF SGQ
Length:2,083
Mass (Da):228,752
Last modified:July 5, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i977306F5EA529610
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAHF01000010 Genomic DNA Translation: EAL86624.1

NCBI Reference Sequences

More...RefSeqi		XP_748662.1, XM_743569.1

Genome annotation databases

Ensembl fungal genome annotation project

More...EnsemblFungii		EAL86624; EAL86624; AFUA_3G03420

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3506154

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		afm:AFUA_3G03420

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHF01000010 Genomic DNA Translation: EAL86624.1
RefSeqiXP_748662.1, XM_743569.1

3D structure databases

SMRiQ4WF53
ModBaseiSearch...

Protein-protein interaction databases

STRINGi746128.CADAFUBP00004398

Proteomic databases

PRIDEiQ4WF53

Genome annotation databases

EnsemblFungiiEAL86624; EAL86624; AFUA_3G03420
GeneIDi3506154
KEGGiafm:AFUA_3G03420

Organism-specific databases

VEuPathDBiFungiDB:Afu3g03420

Phylogenomic databases

eggNOGiKOG1178, Eukaryota
HOGENOMiCLU_000022_60_2_1
InParanoidiQ4WF53
OMAiFNPYPLM
OrthoDBi4243at2759

Family and domain databases

Gene3Di1.10.1200.10, 2 hits
3.30.300.30, 2 hits
3.30.559.10, 2 hits
3.40.50.12780, 1 hit
InterProiView protein in InterPro
IPR010071, AA_adenyl_domain
IPR036736, ACP-like_sf
IPR045851, AMP-bd_C_sf
IPR020845, AMP-binding_CS
IPR000873, AMP-dep_Synth/Lig
IPR042099, ANL_N_sf
IPR023213, CAT-like_dom_sf
IPR001242, Condensatn
IPR020806, PKS_PP-bd
IPR009081, PP-bd_ACP
PfamiView protein in Pfam
PF00501, AMP-binding, 1 hit
PF00668, Condensation, 2 hits
PF00550, PP-binding, 2 hits
SMARTiView protein in SMART
SM00823, PKS_PP, 2 hits
SUPFAMiSSF47336, SSF47336, 2 hits
TIGRFAMsiTIGR01733, AA-adenyl-dom, 1 hit
PROSITEiView protein in PROSITE
PS00455, AMP_BINDING, 1 hit
PS50075, CARRIER, 2 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSIDD_ASPFU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4WF53
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2012
Last sequence update: July 5, 2005
Last modified: February 23, 2022
This is version 95 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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