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UniProtKB - Q4VKV5 (MATRX_TUPVT)
Protein
Matrix protein
Gene
M
Organism
Tupaia virus (isolate Tupaia/Thailand/-/1986) (TUPV)
Status
Functioni
Plays a major role in assembly and budding of virion, by recruiting cellular partners of the ESCRT complexes that play a key role in releasing the budding particle from the host membrane. Condensates the ribonucleocapsid core during virus assembly.
By similarityGO - Molecular functioni
- structural constituent of virion Source: UniProtKB-KW
GO - Biological processi
- viral budding via host ESCRT complex Source: UniProtKB-KW
Keywordsi
Biological process | Host-virus interaction, Viral budding, Viral budding via the host ESCRT complexes, Viral release from host cell |
Names & Taxonomyi
Protein namesi | Recommended name: Matrix protein |
Gene namesi | Name:M |
Organismi | Tupaia virus (isolate Tupaia/Thailand/-/1986) (TUPV) |
Taxonomic identifieri | 1560034 [NCBI] |
Taxonomic lineagei | Viruses › Riboviria › Orthornavirae › Negarnaviricota › Haploviricotina › Monjiviricetes › Mononegavirales › Rhabdoviridae › Alpharhabdovirinae › Tupavirus › |
Virus hosti | Tupaia [TaxID: 9394] |
Proteomesi |
|
Subcellular locationi
- Virion membrane By similarity; Peripheral membrane protein By similarity
- Host endomembrane system By similarity; Peripheral membrane protein By similarity
- Host nucleus membrane By similarity; Peripheral membrane protein By similarity
Keywords - Cellular componenti
Host membrane, Host nucleus, Membrane, Viral matrix protein, VirionPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000432062 | 1 – 200 | Matrix proteinAdd BLAST | 200 |
Interactioni
Subunit structurei
Homomultimer.
Interacts with viral nucleocapsid.
By similarityStructurei
i Sequence
Sequence statusi: Complete.
Q4VKV5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLRWFSFGSN EGSEVAGNGW SVKPIGNMSI KKDDPVGFPQ GYQCLLKVII
60 70 80 90 100
QLEKKDPTKS DVSELIAGWV KRYSGPHLLE RLIKALIILT VPKLSRENID
110 120 130 140 150
NHVKLGGLFE GQVTFHFSSR DLIPTKYLSY ATSIRTTVKG IYSYLSIEAE
160 170 180 190 200
LNPSSHQGTS VAKLLRASDV AKYYDNTLQS IFSQFEIKNV TITDDQIIFN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY840978 Genomic RNA Translation: AAX47599.1 |
RefSeqi | YP_238531.1, NC_007020.1 |
Genome annotation databases
GeneIDi | 3416612 |
KEGGi | vg:3416612 |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY840978 Genomic RNA Translation: AAX47599.1 |
RefSeqi | YP_238531.1, NC_007020.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 3416612 |
KEGGi | vg:3416612 |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | MATRX_TUPVT | |
Accessioni | Q4VKV5Primary (citable) accession number: Q4VKV5 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 4, 2015 |
Last sequence update: | July 5, 2005 | |
Last modified: | September 29, 2021 | |
This is version 35 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Viral Protein Annotation Program |