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Protein

Coiled-coil domain-containing protein 84

Gene

Ccdc84

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Coiled-coil domain-containing protein 84
Gene namesi
Name:Ccdc84
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2685960 Ccdc84

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002710231 – 332Coiled-coil domain-containing protein 84Add BLAST332

Proteomic databases

PaxDbiQ4VA36
PeptideAtlasiQ4VA36
PRIDEiQ4VA36

PTM databases

iPTMnetiQ4VA36
PhosphoSitePlusiQ4VA36

Expressioni

Gene expression databases

BgeeiENSMUSG00000043923
CleanExiMM_CCDC84
ExpressionAtlasiQ4VA36 baseline and differential
GenevisibleiQ4VA36 MM

Interactioni

Protein-protein interaction databases

IntActiQ4VA36, 1 interactor

Structurei

3D structure databases

ProteinModelPortaliQ4VA36
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili137 – 168Sequence analysisAdd BLAST32

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi63 – 71Cys-rich9

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IGQ1 Eukaryota
ENOG410ZPSB LUCA
GeneTreeiENSGT00390000007799
HOGENOMiHOG000111440
HOVERGENiHBG081049
InParanoidiQ4VA36
OMAiPELDWME
OrthoDBiEOG091G0C3X
PhylomeDBiQ4VA36
TreeFamiTF324670

Family and domain databases

InterProiView protein in InterPro
IPR028015 CCDC84
PANTHERiPTHR31198 PTHR31198, 2 hits
PfamiView protein in Pfam
PF14968 CCDC84, 2 hits

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q4VA36-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAPPQRCPLC RQTFFCGRGH VYSHKHQRQL KGALERLLPQ VEAARRAVRA
60 70 80 90 100
AQVERYVPEH DRCCWCPCCG CEVRKHLSHG NLTVLHGGLL EHLASPEHKK
110 120 130 140 150
ATNKFWWENK ANAQMKEKFL ISPQDYARFK KSMVKGLDSY EEKEDEVIKE
160 170 180 190 200
MAAQIREVEQ SRQEVVRSVL EPQAESDPEE GSSAPESWKA TNGHVASSSQ
210 220 230 240 250
QVSHLALQPV AELDWMETGQ QLTFIGHQDT PGIGNIHSGA TPPWMIQEEE
260 270 280 290 300
HSSGSLPIGP SYEEFLKEKE KQKLKKLPPD RVGANFDHSS NTSAGWLPSF
310 320 330
GRVWNNGRRW QSRHQFKTEA ATRSKQPRKG KS
Length:332
Mass (Da):37,701
Last modified:July 5, 2005 - v1
Checksum:i8E8CE080764B00A2
GO
Isoform 2 (identifier: Q4VA36-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-194: PQAESDPEEGSSAPESWKATNGH → VGFPRRTQRTSGRVRSRRGLFST
     195-332: Missing.

Show »
Length:194
Mass (Da):22,541
Checksum:iE0C5CBA0F198311C
GO
Isoform 3 (identifier: Q4VA36-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     172-185: PQAESDPEEGSSAP → VGFPRRTQRSIQIH
     186-332: Missing.

Note: No experimental confirmation available.
Show »
Length:185
Mass (Da):21,558
Checksum:iCED402455BD1C883
GO

Sequence cautioni

The sequence AAH55929 differs from that shown. Reason: Erroneous initiation.Curated

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_022266172 – 194PQAES…ATNGH → VGFPRRTQRTSGRVRSRRGL FST in isoform 2. 2 PublicationsAdd BLAST23
Alternative sequenceiVSP_022268172 – 185PQAES…GSSAP → VGFPRRTQRSIQIH in isoform 3. 1 PublicationAdd BLAST14
Alternative sequenceiVSP_022269186 – 332Missing in isoform 3. 1 PublicationAdd BLAST147
Alternative sequenceiVSP_022267195 – 332Missing in isoform 2. 2 PublicationsAdd BLAST138

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK052757 mRNA Translation: BAC35135.1
AK171754 mRNA Translation: BAE42652.1
BC055929 mRNA Translation: AAH55929.1 Different initiation.
BC096560 mRNA Translation: AAH96560.1
BC116877 mRNA Translation: AAI16878.1
BC116879 mRNA Translation: AAI16880.1
CCDSiCCDS23110.1 [Q4VA36-1]
RefSeqiNP_958760.2, NM_201372.3 [Q4VA36-1]
UniGeneiMm.259573

Genome annotation databases

EnsembliENSMUST00000053286; ENSMUSP00000053216; ENSMUSG00000043923 [Q4VA36-1]
ENSMUST00000213813; ENSMUSP00000148874; ENSMUSG00000043923 [Q4VA36-3]
ENSMUST00000214494; ENSMUSP00000151113; ENSMUSG00000043923 [Q4VA36-2]
ENSMUST00000214702; ENSMUSP00000151118; ENSMUSG00000043923 [Q4VA36-2]
ENSMUST00000217270; ENSMUSP00000150949; ENSMUSG00000043923 [Q4VA36-2]
ENSMUST00000217351; ENSMUSP00000149682; ENSMUSG00000043923 [Q4VA36-2]
GeneIDi382073
KEGGimmu:382073
UCSCiuc009pdo.1 mouse [Q4VA36-1]
uc009pdq.1 mouse [Q4VA36-3]
uc012grv.1 mouse [Q4VA36-2]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiCCD84_MOUSE
AccessioniPrimary (citable) accession number: Q4VA36
Secondary accession number(s): Q3TAL6, Q7TNQ4, Q8C702
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: July 5, 2005
Last modified: November 22, 2017
This is version 78 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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