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Protein
Submitted name:

Transcription factor AP-2 gamma

Gene

Tfap2c

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-3232118 SUMOylation of transcription factors
R-RNO-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors
R-RNO-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-RNO-8866911 TFAP2 (AP-2) family regulates transcription of cell cycle factors

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-2 gammaImported
Submitted name:
Transcription factor AP-2, gammaImported
Gene namesi
Name:Tfap2cImported
Synonyms:Tcfap2cImported
ORF Names:rCG_40857Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 3

Organism-specific databases

RGDi1303185 Tfap2c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000005246 Expressed in 3 organ(s), highest expression level in brain

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006991

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini224 – 418TF_AP-2InterPro annotationAdd BLAST195

Phylogenomic databases

eggNOGiKOG3811 Eukaryota
ENOG410XR9E LUCA
GeneTreeiENSGT00550000074577
HOGENOMiHOG000231737
HOVERGENiHBG002455
KOiK09177
OMAiRPHVERN
OrthoDBiEOG091G0PR6

Family and domain databases

InterProiView protein in InterPro
IPR004979 TF_AP2
IPR013854 TF_AP2_C
IPR008123 TF_AP2_gamma
PANTHERiPTHR10812 PTHR10812, 1 hit
PfamiView protein in Pfam
PF03299 TF_AP-2, 1 hit
PRINTSiPR01751 AP2CTNSCPFCT
PR01748 AP2TNSCPFCT

Sequencei

Sequence statusi: Complete.

Q4V8P9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLWKITDNVK YEEDCEDRHD ASSNGNPRIP HLSSAGQHLY SPAPPLSHTG
60 70 80 90 100
VAEYQPPPYF PPPYQQLAYS QSADHYSHLG EAYAAAINPL HQPAPTGSQQ
110 120 130 140 150
QAWPGRQSQE GSSLASHHGR SAGLIPHISG LEGSAVSSRR EAYRRSDLLL
160 170 180 190 200
PHAHALEAAG LAENLGLHEM AHPIEEVQNV DDPHLLLHDQ TVIRKGPISM
210 220 230 240 250
TKNPLGLPCQ KDLVGAVMNP SEVFCSVPGR LSLLSSTSKY KVTVAEVQRR
260 270 280 290 300
LSPPECLNAS LLGGVLRRAK SKNGGRSLRE KLDKIGLNLP AGRRKAAHVT
310 320 330 340 350
LLTSLVEGEA VHLARDFAYV CEAEFPSKAV ADYLTRPHLG GRNEMAARKS
360 370 380 390 400
VLLAAQQVCK EFTDLLHQDR TPNGNSRPTP VLETNIQNCL SHFSLITHGF
410 420 430 440 450
GSQAICAAVS AVQNYIKEAL ITIDKSYMNP GEQSPADSNK TMEKMEKHRK
Length:450
Mass (Da):49,098
Last modified:July 5, 2005 - v1
Checksum:iB05330591EBBA16A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054819 Genomic DNA No translation available.
BC097260 mRNA Translation: AAH97260.1
CH474062 Genomic DNA Translation: EDL85139.1
RefSeqiNP_958823.2, NM_201420.2
UniGeneiRn.16142

Genome annotation databases

EnsembliENSRNOT00000006991; ENSRNOP00000006991; ENSRNOG00000005246
GeneIDi362280
KEGGirno:362280

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07054819 Genomic DNA No translation available.
BC097260 mRNA Translation: AAH97260.1
CH474062 Genomic DNA Translation: EDL85139.1
RefSeqiNP_958823.2, NM_201420.2
UniGeneiRn.16142

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000006991

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000006991; ENSRNOP00000006991; ENSRNOG00000005246
GeneIDi362280
KEGGirno:362280

Organism-specific databases

CTDi7022
RGDi1303185 Tfap2c

Phylogenomic databases

eggNOGiKOG3811 Eukaryota
ENOG410XR9E LUCA
GeneTreeiENSGT00550000074577
HOGENOMiHOG000231737
HOVERGENiHBG002455
KOiK09177
OMAiRPHVERN
OrthoDBiEOG091G0PR6

Enzyme and pathway databases

ReactomeiR-RNO-3232118 SUMOylation of transcription factors
R-RNO-8866904 Negative regulation of activity of TFAP2 (AP-2) family transcription factors
R-RNO-8866907 Activation of the TFAP2 (AP-2) family of transcription factors
R-RNO-8866911 TFAP2 (AP-2) family regulates transcription of cell cycle factors

Gene expression databases

BgeeiENSRNOG00000005246 Expressed in 3 organ(s), highest expression level in brain

Family and domain databases

InterProiView protein in InterPro
IPR004979 TF_AP2
IPR013854 TF_AP2_C
IPR008123 TF_AP2_gamma
PANTHERiPTHR10812 PTHR10812, 1 hit
PfamiView protein in Pfam
PF03299 TF_AP-2, 1 hit
PRINTSiPR01751 AP2CTNSCPFCT
PR01748 AP2TNSCPFCT
ProtoNetiSearch...

Entry informationi

Entry nameiQ4V8P9_RAT
AccessioniPrimary (citable) accession number: Q4V8P9
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: November 7, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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