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Protein
Submitted name:

GATA zinc finger domain-containing 2B

Gene

Gatad2b

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • negative regulation of transcription by RNA polymerase II Source: GO_Central

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-RNO-6804758 Regulation of TP53 Activity through Acetylation
R-RNO-73762 RNA Polymerase I Transcription Initiation
R-RNO-8943724 Regulation of PTEN gene transcription

Names & Taxonomyi

Protein namesi
Submitted name:
GATA zinc finger domain-containing 2BImported
Gene namesi
Name:Gatad2bImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 2

Organism-specific databases

RGDi1308533 Gatad2b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000015553 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021502

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini414 – 444GATA-typeInterPro annotationAdd BLAST31

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili159 – 186Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG410IQ4W Eukaryota
ENOG410ZCNE LUCA
GeneTreeiENSGT00390000004097
HOGENOMiHOG000074070
HOVERGENiHBG053401
OMAiMNPTINY
TreeFamiTF321369

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR032346 P66_CC
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 1 hit
PF16563 P66_CC, 1 hit
PROSITEiView protein in PROSITE
PS50114 GATA_ZN_FINGER_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q4V8E1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDRMTEDALR LNLLKRSLDP ADERDDVLAK RLKMEGHEAM ERLKMLALLK
60 70 80 90 100
RKDLANLEVP HELPTKQDGS GVKSYEEKLN GNLRPHGDNR TAGRPGKENI
110 120 130 140 150
NDEPVDMSAR RSEPDRGRLT PSPDIIVLSD NEASSPRSSS RMEERLKAAN
160 170 180 190 200
LEMFKGKGIE ERQQLIKQLR DELRLEEARL VLLKKLRQSQ LQKENVVQKT
210 220 230 240 250
PVVQNAASIV QPSPAHVGQQ GLSKLPSRPG AQGIEPQNLR TLQGHSVIRS
260 270 280 290 300
AANTTLPHML MSQRVIAPNP AQLQGQRGPP KPGIVRTTTP NMNPAISYQP
310 320 330 340 350
QSSSSVPCQR TTSSAIYMNL ASHIQPGTVN RVSSPLPSPS AMSDAANSQA
360 370 380 390 400
AAKLALRKQL EKTLLEIPPP KPPAPLLHFL PSAANSEFIY MVGLEEVVQS
410 420 430 440 450
VIDSQGKNCA SLLRVEPFVC AQCRTDFTPH WKQEKNGKIL CEQCMTSNQK
460 470 480 490 500
KALKAEHTNR LKNAFVKALQ QEQEIEQRLQ QQAALSPTTA PAVSSVSKQE
510 520 530 540 550
TIMRHHTLRQ APQPQSSLQR GIPTSARSML SNFAQAPQLS VPGGLLGMPG
560 570 580 590
VNIAYLNTGI GGHKAPSLAD RQREYLLDMI PPRSISQSIS GQK
Length:593
Mass (Da):65,261
Last modified:July 5, 2005 - v1
Checksum:iC30A63C9830B6B4C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07012152 Genomic DNA No translation available.
AABR07012153 Genomic DNA No translation available.
AABR07012154 Genomic DNA No translation available.
BC097428 mRNA Translation: AAH97428.1
RefSeqiNP_001020059.1, NM_001024888.1
XP_008759366.1, XM_008761144.2
UniGeneiRn.133230

Genome annotation databases

EnsembliENSRNOT00000021502; ENSRNOP00000021502; ENSRNOG00000015553
ENSRNOT00000086285; ENSRNOP00000071152; ENSRNOG00000015553
GeneIDi310614
KEGGirno:310614
UCSCiRGD:1308533 rat

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07012152 Genomic DNA No translation available.
AABR07012153 Genomic DNA No translation available.
AABR07012154 Genomic DNA No translation available.
BC097428 mRNA Translation: AAH97428.1
RefSeqiNP_001020059.1, NM_001024888.1
XP_008759366.1, XM_008761144.2
UniGeneiRn.133230

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000021502

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000021502; ENSRNOP00000021502; ENSRNOG00000015553
ENSRNOT00000086285; ENSRNOP00000071152; ENSRNOG00000015553
GeneIDi310614
KEGGirno:310614
UCSCiRGD:1308533 rat

Organism-specific databases

CTDi57459
RGDi1308533 Gatad2b

Phylogenomic databases

eggNOGiENOG410IQ4W Eukaryota
ENOG410ZCNE LUCA
GeneTreeiENSGT00390000004097
HOGENOMiHOG000074070
HOVERGENiHBG053401
OMAiMNPTINY
TreeFamiTF321369

Enzyme and pathway databases

ReactomeiR-RNO-6804758 Regulation of TP53 Activity through Acetylation
R-RNO-73762 RNA Polymerase I Transcription Initiation
R-RNO-8943724 Regulation of PTEN gene transcription

Gene expression databases

BgeeiENSRNOG00000015553 Expressed in 9 organ(s), highest expression level in skeletal muscle tissue

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR032346 P66_CC
IPR000679 Znf_GATA
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00320 GATA, 1 hit
PF16563 P66_CC, 1 hit
PROSITEiView protein in PROSITE
PS50114 GATA_ZN_FINGER_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ4V8E1_RAT
AccessioniPrimary (citable) accession number: Q4V8E1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 5, 2005
Last sequence update: July 5, 2005
Last modified: November 7, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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