UniProtKB - Q4V860 (TFCP2_XENLA)
Protein
Transcription factor CP2
Gene
tfcp2
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
May function as a transcription factor.
GO - Molecular functioni
- DNA binding Source: UniProtKB-KW
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: InterPro
Keywordsi
Molecular function | DNA-binding |
Biological process | Transcription, Transcription regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription factor CP2 |
Gene namesi | Name:tfcp2 |
Organismi | Xenopus laevis (African clawed frog) |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-865546, tfcp2.L |
Subcellular locationi
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000228004 | 1 – 506 | Transcription factor CP2Add BLAST | 506 |
Interactioni
Subunit structurei
Component of the SSP (stage selector protein) complex, which appears to be a heteromer of TFCP2 and 2 copies of NFE4.
By similarityProtein-protein interaction databases
BioGRIDi | 592278, 2 interactors |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 133 – 395 | DNA-bindingBy similarityAdd BLAST | 263 |
Sequence similaritiesi
Phylogenomic databases
OMAi | NEEYTEH |
OrthoDBi | 386296at2759 |
Family and domain databases
CDDi | cd09589, SAM_TFCP2, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR007604, CP2 IPR013761, SAM/pointed_sf IPR041418, SAM_3 IPR040167, TF_CP2-like IPR037599, TFCP2_SAM |
PANTHERi | PTHR11037, PTHR11037, 1 hit |
Pfami | View protein in Pfam PF04516, CP2, 1 hit PF18016, SAM_3, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4V860-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAWALKLPLA DEVIESGLVQ DFDASLSGIG QELGAGAYSM SDVLALPIFK
60 70 80 90 100
QEESSLPSEN ENKILPFQYV LCTATSPAVK LHEETLTYLN QGQSYEIRML
110 120 130 140 150
DNRKIGELPE LNGKLVKSIF RVVFHDRRLQ YTEHQQLEGW RWNRPGDRIL
160 170 180 190 200
DIDIPMSVGI IDPRANPTQL NTIEFLWDPA KRTSVFIQVH CISTEFTMRK
210 220 230 240 250
HGGEKGVPFR VQIDTFKENE NGEYTEHLHS ASSQIKVFKP KGADRKQKTD
260 270 280 290 300
REKMEKRTPQ EKEKYQPSYE TTILTECSPW PEITYVSNSP SPGFNSSHNS
310 320 330 340 350
FPIGEGNGSP NHQPEPPAPI VDVSAGLTPI QNLMPTSTPQ EAQQWLHRNR
360 370 380 390 400
FAAFSRLFTN FSGADLLKLT REDVIQICGP ADGIRLFNAL KGRIVRPRLT
410 420 430 440 450
IYVCQESQQL REQQQHKHEN GEPGNGAFYV YHAIYLEEMT TIELTEKIAQ
460 470 480 490 500
LFSISPHQIN QIYKQGPTGI HVLISDEMIQ NFQDESCFIL DTMKAETNDS
YHIILK
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC097529 mRNA Translation: AAH97529.1 |
RefSeqi | NP_001089447.1, NM_001095978.1 |
Genome annotation databases
GeneIDi | 734497 |
KEGGi | xla:734497 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC097529 mRNA Translation: AAH97529.1 |
RefSeqi | NP_001089447.1, NM_001095978.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
BioGRIDi | 592278, 2 interactors |
Genome annotation databases
GeneIDi | 734497 |
KEGGi | xla:734497 |
Organism-specific databases
CTDi | 734497 |
Xenbasei | XB-GENE-865546, tfcp2.L |
Phylogenomic databases
OMAi | NEEYTEH |
OrthoDBi | 386296at2759 |
Family and domain databases
CDDi | cd09589, SAM_TFCP2, 1 hit |
Gene3Di | 1.10.150.50, 1 hit |
InterProi | View protein in InterPro IPR007604, CP2 IPR013761, SAM/pointed_sf IPR041418, SAM_3 IPR040167, TF_CP2-like IPR037599, TFCP2_SAM |
PANTHERi | PTHR11037, PTHR11037, 1 hit |
Pfami | View protein in Pfam PF04516, CP2, 1 hit PF18016, SAM_3, 1 hit |
SUPFAMi | SSF47769, SSF47769, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TFCP2_XENLA | |
Accessioni | Q4V860Primary (citable) accession number: Q4V860 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 21, 2006 |
Last sequence update: | July 5, 2005 | |
Last modified: | December 2, 2020 | |
This is version 54 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |