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Protein

tRNA pseudouridine synthase D

Gene

truD

Organism
Xanthomonas campestris pv. campestris (strain 8004)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(13) = tRNA pseudouridine(13).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase DUniRule annotation (EC:5.4.99.27UniRule annotation)
Alternative name(s):
tRNA pseudouridine(13) synthaseUniRule annotation
tRNA pseudouridylate synthase DUniRule annotation
tRNA-uridine isomerase DUniRule annotation
Gene namesi
Name:truDUniRule annotation
Ordered Locus Names:XC_2527
OrganismiXanthomonas campestris pv. campestris (strain 8004)
Taxonomic identifieri314565 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaXanthomonadalesXanthomonadaceaeXanthomonas
Proteomesi
  • UP000000420 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002301561 – 367tRNA pseudouridine synthase DAdd BLAST367

Interactioni

Protein-protein interaction databases

STRINGi314565.XC_2527

Structurei

3D structure databases

ProteinModelPortaliQ4UTP6
SMRiQ4UTP6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini156 – 316TRUDUniRule annotationAdd BLAST161

Sequence similaritiesi

Belongs to the pseudouridine synthase TruD family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit

Sequencei

Sequence statusi: Complete.

Q4UTP6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDSPVLPRA HGAAVLTAAM RSVAEDFQVD ELPAFDASGE GEHLLLTVRK
60 70 80 90 100
RGQNTAYVAK RLAQWAGIAE MGIGYAGLKD RHAVTTQRFS VHLPKRIAPD
110 120 130 140 150
LSALDDDDMQ VVEHTWHNRK LQRGALHGNR FVLTLREVVG DQAVIDARLH
160 170 180 190 200
AIAARGIPNW FGEQRFGRDG GNVAAALAMF GHTRQPDGTL APAPKRRLRN
210 220 230 240 250
DQRSLLLSAA RSALFNQVLT ARVEQGNWDA PLDGEAWMLD GSRSVFGPEP
260 270 280 290 300
WSEVLAERLA RFDIHPSGPL WGAGELRCSA DAAAIEQAAL SDPQSLALRT
310 320 330 340 350
GLEAAGLKQE RRALRLRPQG LAHAWLDAQT LQLTFALPPG CYATAVLWEL
360
GEVVDAARVA PQSRSEG
Length:367
Mass (Da):39,901
Last modified:July 5, 2005 - v1
Checksum:iEC9FC3814FA32A87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000050 Genomic DNA Translation: AAY49577.1
RefSeqiWP_011036881.1, NC_007086.1

Genome annotation databases

EnsemblBacteriaiAAY49577; AAY49577; XC_2527
KEGGixcb:XC_2527

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000050 Genomic DNA Translation: AAY49577.1
RefSeqiWP_011036881.1, NC_007086.1

3D structure databases

ProteinModelPortaliQ4UTP6
SMRiQ4UTP6
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi314565.XC_2527

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAY49577; AAY49577; XC_2527
KEGGixcb:XC_2527

Phylogenomic databases

eggNOGiENOG4106NZV Bacteria
COG0585 LUCA
HOGENOMiHOG000224848
KOiK06176
OMAiLWLWVEK
OrthoDBiPOG091H03KK

Family and domain databases

HAMAPiMF_01082 TruD, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001656 PsdUridine_synth_TruD
IPR020119 PsdUridine_synth_TruD_CS
IPR011760 PsdUridine_synth_TruD_insert
PANTHERiPTHR13326 PTHR13326, 2 hits
PfamiView protein in Pfam
PF01142 TruD, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
PROSITEiView protein in PROSITE
PS50984 TRUD, 1 hit
PS01268 UPF0024, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTRUD_XANC8
AccessioniPrimary (citable) accession number: Q4UTP6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: July 5, 2005
Last modified: November 7, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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