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Entry version 83 (31 Jul 2019)
Sequence version 1 (19 Jul 2005)
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Protein
Submitted name:

Chromosome 11 SCAF14674, whole genome shotgun sequence

Gene

GSTENG00021024001

Organism
Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromosome 11 SCAF14674, whole genome shotgun sequenceImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:GSTENG00021024001Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri99883 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTetraodon

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini110 – 160Guanylate kinase-likeInterPro annotationAdd BLAST51
Domaini285 – 318WWInterPro annotationAdd BLAST34
Domaini471 – 540PDZInterPro annotationAdd BLAST70
Domaini655 – 733PDZInterPro annotationAdd BLAST79
Domaini865 – 947PDZInterPro annotationAdd BLAST83
Domaini1052 – 1148PDZInterPro annotationAdd BLAST97
Domaini1215 – 1297PDZInterPro annotationAdd BLAST83

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni151 – 290DisorderedSequence analysisAdd BLAST140
Regioni367 – 400DisorderedSequence analysisAdd BLAST34
Regioni583 – 637DisorderedSequence analysisAdd BLAST55
Regioni777 – 841DisorderedSequence analysisAdd BLAST65
Regioni955 – 1018DisorderedSequence analysisAdd BLAST64

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi185 – 211PolarSequence analysisAdd BLAST27
Compositional biasi251 – 277PolarSequence analysisAdd BLAST27
Compositional biasi583 – 614PolarSequence analysisAdd BLAST32
Compositional biasi621 – 637PolarSequence analysisAdd BLAST17
Compositional biasi777 – 807PolarSequence analysisAdd BLAST31
Compositional biasi812 – 826Pro-richSequence analysisAdd BLAST15
Compositional biasi963 – 1006PolarSequence analysisAdd BLAST44

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113200

KEGG Orthology (KO)

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KOi
K05631

Family and domain databases

Conserved Domains Database

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CDDi
cd00201 WW, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR030033 MAGI1
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR001202 WW_dom
IPR036020 WW_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR10316:SF12 PTHR10316:SF12, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF00595 PDZ, 5 hits
PF00397 WW, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00072 GuKc, 1 hit
SM00228 PDZ, 5 hits
SM00456 WW, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 5 hits
SSF51045 SSF51045, 1 hit
SSF52540 SSF52540, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS50106 PDZ, 5 hits
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4SBD0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MREVVESGSL AAFKIKKSVR FRQDDGVSEA VSPMANLQTE TGGEVGEDTL
60 70 80 90 100
ALGHQPSVTQ VEPNRVLEEG IKWLLIYNSS SGKMKNRGRI CPTVTIFTKS
110 120 130 140 150
VIFKDRRCGT TRAPREGEVP GIDYNFLSVD DFFKLEKSGT LLEIGTYEGN
160 170 180 190 200
YYGTPRPPVQ PPGGKVISSS GGSGDAPLPD GLSGSLPGSQ HSTPRRSKSY
210 220 230 240 250
NDMQNAGIGP GESQQEDDED LPDMNSSFTG DSSELDDIHH SVRPFAPHRS
260 270 280 290 300
DPSYSGTTPS PTATTESTQQ THSHLSHPPS EDPLGPLPEN WEMAYTEDGE
310 320 330 340 350
VYFIDHNTKT TSWVDPRCLN KPQKPLEECE DDEGVHTEEL DNDLELPPGW
360 370 380 390 400
EKIDDPVYGV YYVEGGGGPP PTHFPPPRRL RGVEAGTEQP QPQSQQPPEG
410 420 430 440 450
ERYIQEWIED SALAGAPLAS YAATQQETYR DPQTGPTVPS AMGQKQHNQL
460 470 480 490 500
CLGGKPFFTR NRSELKGTFI NTKLKKSRRG FGFTVVGGDE PDEFLQIKSL
510 520 530 540 550
VLDGPAALDG KMETGDVIVS VNDTCVLGYT HAQVVKIFQS IPIGSMVNLE
560 570 580 590 600
LCRGYPLPFD PDDPNTSLVT SVAILENKDP IIVNGQEDSN SYDSPSSHSS
610 620 630 640 650
QNNNGSSNGG APLNGLPRAS SPSVEVASDT SSQHGYPSDV VTLASSIATQ
660 670 680 690 700
PELITVHMEK GEKGFGFTIA DSPGGGGQRV KQIVDYPRCR GLKEGDIIVE
710 720 730 740 750
VNKRNVQSMS HNQVVDLLSK CTKGSEVTML VQRGVATAKK SPKLNDFELA
760 770 780 790 800
PPYRDYTRRL DILLRNLIDL LLQKKQLSRK DSQNSSQHSV SSHRSIHTDS
810 820 830 840 850
PAHSSLAAPL SESVAPPPPS QPLPSLPSQD SPADGTIQRK PDPFKIWAQS
860 870 880 890 900
RSMYESRLPD FQEQDIFLWR KDTGFGFRIL GGNEPGEPIY IGHIVKYGAA
910 920 930 940 950
DEDGRLRSGD ELICVDGTAV VGKSHQLVVQ LMQQAAKQGH VNLTVRRKTS
960 970 980 990 1000
YAVKAEGDVP PSPASSHHSS TQAPSLTEEM GKRTLQGSQN SLNTVSSGSG
1010 1020 1030 1040 1050
STSGIGSGGG GGGGGGGVGG GANSVVPAVA ATTSSQPLNA TSAVSSPLQP
1060 1070 1080 1090 1100
YDVEIRRGEN EGFGFVIVSS VSRPEAGTTF AGNACVAMPH KIGRIIEGSP
1110 1120 1130 1140 1150
ADRCGKLKVG DRILAVNGCS ITNKSHSDIV NLIKEAGNTV TLRIIPGDES
1160 1170 1180 1190 1200
SNASLLTNAE KIATITTTHT PQQQAAPETR TNTKPKQESY EFKAPQVAPP
1210 1220 1230 1240 1250
QPPTQISSQD AEFYSVDLER DNKGFGFSLR GGREYNMDLY VLRLAEDGAA
1260 1270 1280 1290 1300
VRNGKMRVGD EILEINGEST KGMKHARAIE LIKSGGRRVH LVLKRGDGSV
1310
PEYGGSIYEN IPFSPIFTP
Length:1,319
Mass (Da):141,898
Last modified:July 19, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEE12F6AF0676BACD
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CAAE01014674 Genomic DNA Translation: CAG02052.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tng:GSTEN00021024G001

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAE01014674 Genomic DNA Translation: CAG02052.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGitng:GSTEN00021024G001

Phylogenomic databases

HOGENOMiHOG000113200
KOiK05631

Family and domain databases

CDDicd00201 WW, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR020590 Guanylate_kinase_CS
IPR030033 MAGI1
IPR027417 P-loop_NTPase
IPR001478 PDZ
IPR036034 PDZ_sf
IPR001202 WW_dom
IPR036020 WW_dom_sf
PANTHERiPTHR10316:SF12 PTHR10316:SF12, 2 hits
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
PF00595 PDZ, 5 hits
PF00397 WW, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SM00228 PDZ, 5 hits
SM00456 WW, 2 hits
SUPFAMiSSF50156 SSF50156, 5 hits
SSF51045 SSF51045, 1 hit
SSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit
PS50106 PDZ, 5 hits
PS01159 WW_DOMAIN_1, 1 hit
PS50020 WW_DOMAIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4SBD0_TETNG
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4SBD0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: July 31, 2019
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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