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Entry version 97 (11 Dec 2019)
Sequence version 1 (19 Jul 2005)
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Protein
Submitted name:

Chromosome 6 SCAF14737, whole genome shotgun sequence

Gene

GSTENG00023908001

Organism
Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Chromosome 6 SCAF14737, whole genome shotgun sequenceImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:GSTENG00023908001Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTetraodon nigroviridis (Spotted green pufferfish) (Chelonodon nigroviridis)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri99883 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataEupercariaTetraodontiformesTetradontoideaTetraodontidaeTetraodon

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini12 – 177PPIase cyclophilin-typeInterPro annotationAdd BLAST166
Domaini1448 – 1516BTBInterPro annotationAdd BLAST69
Domaini1803 – 1831C2H2-typeInterPro annotationAdd BLAST29
Domaini1869 – 1897C2H2-typeInterPro annotationAdd BLAST29
Domaini1899 – 1926C2H2-typeInterPro annotationAdd BLAST28
Domaini1927 – 1954C2H2-typeInterPro annotationAdd BLAST28
Domaini1955 – 1982C2H2-typeInterPro annotationAdd BLAST28
Domaini1983 – 2010C2H2-typeInterPro annotationAdd BLAST28
Domaini2011 – 2038C2H2-typeInterPro annotationAdd BLAST28
Domaini2039 – 2072C2H2-typeInterPro annotationAdd BLAST34

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni186 – 639DisorderedSequence analysisAdd BLAST454
Regioni657 – 747DisorderedSequence analysisAdd BLAST91
Regioni762 – 874DisorderedSequence analysisAdd BLAST113
Regioni888 – 1089DisorderedSequence analysisAdd BLAST202
Regioni1110 – 1333DisorderedSequence analysisAdd BLAST224
Regioni1551 – 1574DisorderedSequence analysisAdd BLAST24
Regioni1680 – 1749DisorderedSequence analysisAdd BLAST70
Regioni1775 – 1795DisorderedSequence analysisAdd BLAST21
Regioni2117 – 2137DisorderedSequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi200 – 215PolarSequence analysisAdd BLAST16
Compositional biasi223 – 242BasicSequence analysisAdd BLAST20
Compositional biasi259 – 283PolyampholyteSequence analysisAdd BLAST25
Compositional biasi296 – 310PolyampholyteSequence analysisAdd BLAST15
Compositional biasi327 – 341BasicSequence analysisAdd BLAST15
Compositional biasi347 – 374PolyampholyteSequence analysisAdd BLAST28
Compositional biasi383 – 404PolyampholyteSequence analysisAdd BLAST22
Compositional biasi420 – 452BasicSequence analysisAdd BLAST33
Compositional biasi453 – 470PolyampholyteSequence analysisAdd BLAST18
Compositional biasi471 – 486PolarSequence analysisAdd BLAST16
Compositional biasi510 – 524BasicSequence analysisAdd BLAST15
Compositional biasi525 – 541PolarSequence analysisAdd BLAST17
Compositional biasi542 – 586BasicSequence analysisAdd BLAST45
Compositional biasi615 – 635Pro-richSequence analysisAdd BLAST21
Compositional biasi669 – 686PolyampholyteSequence analysisAdd BLAST18
Compositional biasi688 – 702PolarSequence analysisAdd BLAST15
Compositional biasi703 – 719BasicSequence analysisAdd BLAST17
Compositional biasi732 – 747PolyampholyteSequence analysisAdd BLAST16
Compositional biasi778 – 793PolyampholyteSequence analysisAdd BLAST16
Compositional biasi794 – 810PolarSequence analysisAdd BLAST17
Compositional biasi811 – 826PolyampholyteSequence analysisAdd BLAST16
Compositional biasi903 – 943BasicSequence analysisAdd BLAST41
Compositional biasi963 – 1010PolyampholyteSequence analysisAdd BLAST48
Compositional biasi1119 – 1140PolarSequence analysisAdd BLAST22
Compositional biasi1142 – 1173PolyampholyteSequence analysisAdd BLAST32
Compositional biasi1191 – 1234PolarSequence analysisAdd BLAST44
Compositional biasi1235 – 1253BasicSequence analysisAdd BLAST19
Compositional biasi1254 – 1272PolarSequence analysisAdd BLAST19
Compositional biasi1307 – 1322PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1686 – 1702AcidicSequence analysisAdd BLAST17
Compositional biasi1703 – 1717PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1718 – 1736AcidicSequence analysisAdd BLAST19

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0546 Eukaryota
COG0652 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000060246

KEGG Orthology (KO)

More...
KOi
K12740

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000210 BTB/POZ_dom
IPR029000 Cyclophilin-like_dom_sf
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00651 BTB, 1 hit
PF00160 Pro_isomerase, 1 hit
PF00096 zf-C2H2, 4 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00153 CSAPPISMRASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 9 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50891 SSF50891, 1 hit
SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50097 BTB, 1 hit
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q4S537-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
ITMGVKDRPQ CYFDVELNRE PVGRIVFQLF SDICPKTCKN FLSLCTGERG
60 70 80 90 100
SGKITGKKLC YKGSTFHRVV KNFMIQGGDF TEGNGRGGES IYGGYFEDEN
110 120 130 140 150
FVLKHDSAFL LSMANRGKDT NGSQFFITTK MAPHLDGVHV VFGLVISGFE
160 170 180 190 200
VVKKIEGLKT DAASRPYADV RVVDCGQLIT KSANDVLQGK RKRASRSAHS
210 220 230 240 250
SPSSHESSQF SSAEGGSEPE EKHKHRKHKK PKNKRSKKKR RESKKENVLP
260 270 280 290 300
PTQRSSQSPE KREIPEGEKE QSGKREKPVV RPEEIPPVPE NRFLLRRDVP
310 320 330 340 350
TQEEKTETVE NPEAFPSADQ KPAVSKSGRK IRGRGTMRYH TPTRSKSRSA
360 370 380 390 400
SVEERADSET PPHWKEEMKK TKVYQPPSLE RWSRGDRLND DSSGRWDDRS
410 420 430 440 450
DSAWSRSPGH SSDRSSKRSS PRRQQKKEKK KAKHKKKAKK RKHGKKKRSK
460 470 480 490 500
IKARSDYRSE GERSLSSERK RGGSRSSSCC SSSRYASSVR RRRRSSVSFR
510 520 530 540 550
GSRSFSRSHT SSHSRSRGRT KSYSPSRSRS HSPSHSPSRS QSHSRTRSRS
560 570 580 590 600
RSRSRYRSRS SSRRRRRRRR RRSFSRSPRK KKSSKSSSRN MVPGPDKPPD
610 620 630 640 650
RTGTSSLKLP AAPAPESVPV IPLSDSPPPS RWKPGQKPWK PSYIHIEEIK
660 670 680 690 700
AKVVANISSG PTADGVTDKP QAENDRASEK SRRSTSHSSR SKSYSHSYSR
710 720 730 740 750
SRSRSYSRSR SRNRYRSRSS SRSQSHSGTS RRKQSHKTDS LHKNWKEYHH
760 770 780 790 800
SVEKGKYLDK YSSCTGSQEA ASGSEKSPDI DVPERRRSSG ESFKNPSDWD
810 820 830 840 850
SDSDQVSRSN GITEAKKEKH ALQAGEGVEK KVSALAGWNS GSDGNISPSR
860 870 880 890 900
AVVISEKEEG EASSDSDCGI YRETSEAVDA LEKKIAAVVS SQSDQSPRRS
910 920 930 940 950
PGAEKHRSKK KAKRKHKRKR SQSKSGSHHG KEKAKRAKRK QQKLKETFHW
960 970 980 990 1000
QPPLEFGEEE EEDDSKRERH SPTKAVKEKP AVAGSKAKDP HPTSSNRKTP
1010 1020 1030 1040 1050
ETRGHQRAKQ AEPHVQPSAS GKEQDSLDDM DICTPEHVSE IVAPSVFQDP
1060 1070 1080 1090 1100
HPKTPGPTLN STSKPPHSPS KEPPSLSPTA PTGGLAEDAA AVPPAGAVLH
1110 1120 1130 1140 1150
FKWKPLKGMA AVPKASASPA ALKSSQAEES QGSSAQAVRM EIKNKSRIRP
1160 1170 1180 1190 1200
GSLFDEVRKT ARLNQRPRNQ ESSSEERSPS VGKAKAPSCP RSAEQSRSVS
1210 1220 1230 1240 1250
RQSRSVSSAR SSSRGWSRSY SRSRSRSRSS SYSSRSHSRS RRRRGRGRTH
1260 1270 1280 1290 1300
SRSSTYRSYR SNSRTYSRSP SRSRSYGRHR RSSRSDSYDS YSSRSRSVSR
1310 1320 1330 1340 1350
RRGRRHSDSY RSLDRRSRCG GPESSQTRDG GEGCVLRMQA STCTSGRVKT
1360 1370 1380 1390 1400
CTEPPSDLPA ADFCTQVAAW RIRPRPLAAV SPQTARAAKA AADAESVSGA
1410 1420 1430 1440 1450
PLSSVLLIVE KTSEFPTAEF SLVEDVALHF TCLMDRLNQQ RLFQPDLCDV
1460 1470 1480 1490 1500
DIVLVRQHST FPAHKGVLAA YSPFFHSLFA QSKQLRRVDL SLDALTSQGL
1510 1520 1530 1540 1550
QQILNFIYTS KLLVSSRTVR DVLNAATLLQ MSDIAASCRD LISNHSLRTS
1560 1570 1580 1590 1600
AEGMASGGES AAAKASPGRR YPEIKQESEL ARGYRREGGG HFSVRVEDAG
1610 1620 1630 1640 1650
KTASHYPKEE GPMGGASAGV ASLCKAESNG EESKAADGHG SFNRDQIIVE
1660 1670 1680 1690 1700
VNLNNQTLNV SKGSEGKSVA RATAIFGRRC EKESVSEDDE ENEEENVDTV
1710 1720 1730 1740 1750
EDEDDLVLRR GDMLGQSSEE EAEEEEADEE EEENTLNIPC LEQPAAMERP
1760 1770 1780 1790 1800
RRGSRAFAVA GTAASLRQTL AEATLANRRQ GGRRAPDGEA PGQKVRLEEK
1810 1820 1830 1840 1850
QHFPCKKCPR VFNNRWYLEK HMNVTHNRMQ SCSHCSKRFL LESELLLHQQ
1860 1870 1880 1890 1900
TDCEKSIQVQ ELFLARFCPH CVTCGKAFKK LWSLHEHNKI VHGYAEKKFS
1910 1920 1930 1940 1950
CEICEKKFYT MAHVRKHMVA HTKDMPFTCE TCGKSFKRSM SLKVHSLQHS
1960 1970 1980 1990 2000
GEKPFKCENC SERFQYKYQL RSHMSIHIGH KQFMCQWCGK DFNMKQYFDE
2010 2020 2030 2040 2050
HMKTHTGEKP YICEICGKSF TSRPNMKRHR RTHTGEKPYP CEVCGQRFRF
2060 2070 2080 2090 2100
SNMLKAHREK CFRISNPAGL DPPLSSPAAE SGGPAELAML PVTPVSAPTA
2110 2120 2130
ASNPQPLRGS HLSLPLLRST AGVPPTPHLP TPPPLFC
Length:2,137
Mass (Da):238,831
Last modified:July 19, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2B5655D087B933C7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1
Non-terminal residuei2137Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CAAE01014737 Genomic DNA Translation: CAG04245.1

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
tng:GSTEN00023908G001

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CAAE01014737 Genomic DNA Translation: CAG04245.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

KEGGitng:GSTEN00023908G001

Phylogenomic databases

eggNOGiKOG0546 Eukaryota
COG0652 LUCA
HOGENOMiHOG000060246
KOiK12740

Family and domain databases

Gene3Di2.40.100.10, 1 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR029000 Cyclophilin-like_dom_sf
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
IPR011333 SKP1/BTB/POZ_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF00651 BTB, 1 hit
PF00160 Pro_isomerase, 1 hit
PF00096 zf-C2H2, 4 hits
PRINTSiPR00153 CSAPPISMRASE
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SM00355 ZnF_C2H2, 9 hits
SUPFAMiSSF50891 SSF50891, 1 hit
SSF54695 SSF54695, 1 hit
SSF57667 SSF57667, 5 hits
PROSITEiView protein in PROSITE
PS50097 BTB, 1 hit
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 7 hits
PS50157 ZINC_FINGER_C2H2_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4S537_TETNG
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4S537
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: December 11, 2019
This is version 97 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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