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Protein

Endoplasmic reticulum-Golgi intermediate compartment protein 3

Gene

ERGIC3

Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Possible role in transport between endoplasmic reticulum and Golgi.By similarity

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Gene namesi
Name:ERGIC3
ORF Names:QtsA-11239
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 25CytoplasmicSequence analysisAdd BLAST25
Transmembranei26 – 46HelicalSequence analysisAdd BLAST21
Topological domaini47 – 340LumenalSequence analysisAdd BLAST294
Transmembranei341 – 361HelicalSequence analysisAdd BLAST21
Topological domaini362 – 382CytoplasmicSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002393881 – 382Endoplasmic reticulum-Golgi intermediate compartment protein 3Add BLAST382

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineBy similarity1
Modified residuei116PhosphoserineBy similarity1
Glycosylationi265N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Acetylation, Glycoprotein, Phosphoprotein

Interactioni

Subunit structurei

Interacts with ERGIC1/ERGIC32.By similarity

Family & Domainsi

Sequence similaritiesi

Belongs to the ERGIC family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG105706
KOiK20367

Family and domain databases

InterProiView protein in InterPro
IPR012936 Erv_C
PfamiView protein in Pfam
PF07970 COPIIcoated_ERV, 1 hit

Sequencei

Sequence statusi: Complete.

Q4R8X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEALGKLKQF DAYPKTLEDF RVKTCGGATV TIVSGLLMLL LFLSELQYYL
60 70 80 90 100
TTEVHPELYV DKSRGDKLKI NIDVLFPHMP CAYLSIDAMD VAGEQQLDVE
110 120 130 140 150
HNLFKQRLDK DGTPVSSEAE RHELGKVEVT VFGPDSLDPD RCESCYGAEA
160 170 180 190 200
EDIKCCNTCE DVREAYRRRG AFKNPDTIEQ CRREGFSQKM QEQKNEGCQV
210 220 230 240 250
YGFLEVNKVA GNFHFAPGKS FQQSHVHVHD LQSFGLDNIN MTHYIQHLSF
260 270 280 290 300
GEDYPGIVNP LDHTNVTAPQ ASMMFQYFVK VVPTVYMKVD GEVLRTNQFS
310 320 330 340 350
VTRHEKVANG LLGDQGLPGV FVLYELSPMM VKLTEKHRSF THFLTGVCAI
360 370 380
IGGMFTVAGL IDSLIYHSAR AIQKKIDLGK TT
Length:382
Mass (Da):42,966
Last modified:July 19, 2005 - v1
Checksum:iADF98F5974D74239
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB168326 mRNA Translation: BAE00450.1
RefSeqiNP_001270982.1, NM_001284053.1
UniGeneiMfa.6763

Genome annotation databases

GeneIDi101866368
KEGGimcf:101866368

Similar proteinsi

Entry informationi

Entry nameiERGI3_MACFA
AccessioniPrimary (citable) accession number: Q4R8X1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 13, 2006
Last sequence update: July 19, 2005
Last modified: May 10, 2017
This is version 39 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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