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Protein

O-acyltransferase

Gene
N/A
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei460UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAcyltransferaseUniRule annotationImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
O-acyltransferaseUniRule annotation
OrganismiMacaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)Imported
Taxonomic identifieri9541 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei141 – 162HelicalSequence analysisAdd BLAST22
Transmembranei182 – 203HelicalSequence analysisAdd BLAST22
Transmembranei224 – 244HelicalSequence analysisAdd BLAST21
Transmembranei320 – 341HelicalSequence analysisAdd BLAST22
Transmembranei361 – 389HelicalSequence analysisAdd BLAST29
Transmembranei447 – 464HelicalSequence analysisAdd BLAST18
Transmembranei470 – 489HelicalSequence analysisAdd BLAST20
Transmembranei501 – 520HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

Family & Domainsi

Sequence similaritiesi

Belongs to the membrane-bound acyltransferase family. Sterol o-acyltransferase subfamily.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00530000063122
HOVERGENiHBG058198
KOiK00637

Family and domain databases

InterProiView protein in InterPro
IPR004299 MBOAT_fam
IPR014371 Oat_ACAT_DAG_ARE
IPR030687 Sterol_acyltranf_meta
PANTHERiPTHR10408 PTHR10408, 1 hit
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit
PIRSFiPIRSF000439 Oat_ACAT_DAG_ARE, 1 hit
PIRSF500230 Sterol_acyltranf_ACAT, 1 hit

Sequencei

Sequence statusi: Complete.

Q4R775-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVGEEKMSLR NRLSKSRENP EEDEDQRKPA KESLEAPSNG RIDIKQLIAK
60 70 80 90 100
KIKLTAEAEE LKPFFMKEVG SHFDDFVTNL IEKSASLDNG GCALTTFSIL
110 120 130 140 150
EGEKNNHRAK DLRAPPEQGK IFIARRSLLD ELLEVDHIRT IYHMFIALLI
160 170 180 190 200
LFILSTLVVD YIDEGRLVLE FSLLSYAFGK FPTVVWTWWI MFLSTFSVPY
210 220 230 240 250
FLFQRWATGY SKSSHPLINS LFHGFLFMVF QIGILGFGPT YVVLAYTLPP
260 270 280 290 300
ASRFIIIFEQ IRFVMKAHSF VRENVPRVLN SAKEKSSTVP IPTVNQYLYF
310 320 330 340 350
LFAPTLIYRD SYPRNPTVRW GYVAMQFAQV FGCFFYVYYI FERLCAPLFR
360 370 380 390 400
NIKQEPFSAR VLVLCVFNSI LPGVLILFLT FFAFLHCWLN AFAEMLRFGD
410 420 430 440 450
RMFYKDWWNS TSYSNYYRTW NVVVHDWLYY YAYKDFLWFF SKRFKSAAML
460 470 480 490 500
AVFAVSAVVH EYALAVCLSF FYPVLFVLFM FFGMAFNFIV NDSRKKPIWN
510 520 530 540 550
VMMWTSLFLG NGVLLCFYSQ EWYARQHCPL KNPTFLDYVR PRSWTCRYVF
Length:550
Mass (Da):64,728
Last modified:July 19, 2005 - v1
Checksum:i3B5E4CF8DB6CC713
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01000893 Genomic DNA No translation available.
AQIA01000894 Genomic DNA No translation available.
AQIA01000895 Genomic DNA No translation available.
AQIA01000896 Genomic DNA No translation available.
AQIA01000897 Genomic DNA No translation available.
AQIA01000898 Genomic DNA No translation available.
AQIA01000899 Genomic DNA No translation available.
AQIA01000900 Genomic DNA No translation available.
AQIA01000901 Genomic DNA No translation available.
AB168948 mRNA Translation: BAE01048.1
RefSeqiNP_001274221.1, NM_001287292.1
UniGeneiMfa.5410

Genome annotation databases

EnsembliENSMFAT00000006594; ENSMFAP00000032373; ENSMFAG00000037136
GeneIDi102121286
KEGGimcf:102121286

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AQIA01000893 Genomic DNA No translation available.
AQIA01000894 Genomic DNA No translation available.
AQIA01000895 Genomic DNA No translation available.
AQIA01000896 Genomic DNA No translation available.
AQIA01000897 Genomic DNA No translation available.
AQIA01000898 Genomic DNA No translation available.
AQIA01000899 Genomic DNA No translation available.
AQIA01000900 Genomic DNA No translation available.
AQIA01000901 Genomic DNA No translation available.
AB168948 mRNA Translation: BAE01048.1
RefSeqiNP_001274221.1, NM_001287292.1
UniGeneiMfa.5410

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMFAT00000006594; ENSMFAP00000032373; ENSMFAG00000037136
GeneIDi102121286
KEGGimcf:102121286

Organism-specific databases

CTDi6646

Phylogenomic databases

GeneTreeiENSGT00530000063122
HOVERGENiHBG058198
KOiK00637

Family and domain databases

InterProiView protein in InterPro
IPR004299 MBOAT_fam
IPR014371 Oat_ACAT_DAG_ARE
IPR030687 Sterol_acyltranf_meta
PANTHERiPTHR10408 PTHR10408, 1 hit
PfamiView protein in Pfam
PF03062 MBOAT, 1 hit
PIRSFiPIRSF000439 Oat_ACAT_DAG_ARE, 1 hit
PIRSF500230 Sterol_acyltranf_ACAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ4R775_MACFA
AccessioniPrimary (citable) accession number: Q4R775
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: March 28, 2018
This is version 46 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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