UniProtKB - Q4QDK0 (Q4QDK0_LEIMA)
Protein
Submitted name:
ATP/ADP translocase
Gene
ANC2
Organism
Leishmania major
Status
Functioni
GO - Molecular functioni
- ATP:ADP antiporter activity Source: InterPro
GO - Biological processi
- mitochondrial ADP transmembrane transport Source: InterPro
- mitochondrial ATP transmembrane transport Source: InterPro
Keywordsi
Biological process | TransportUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: ATP/ADP translocaseImportedSubmitted name: Putative ADP/ATP translocase 1Imported |
Gene namesi | Name:ANC2Imported Synonyms:ANC1Imported ORF Names:LMJF_19_0200Imported, LMJF_19_0210Imported |
Organismi | Leishmania majorImported |
Taxonomic identifieri | 5664 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | TriTrypDB:LmjF.19.0200 TriTrypDB:LmjF.19.0210 |
Subcellular locationi
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 127 – 149 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 190 – 212 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 224 – 245 | HelicalSequence analysisAdd BLAST | 22 |
GO - Cellular componenti
- integral component of membrane Source: UniProtKB-UniRule
- mitochondrial inner membrane Source: InterPro
- mitochondrion Source: GeneDB
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 25 – 114 | SolcarPROSITE-ProRule annotationAdd BLAST | 90 | |
Repeati | 126 – 218 | SolcarPROSITE-ProRule annotationAdd BLAST | 93 | |
Repeati | 222 – 308 | SolcarPROSITE-ProRule annotationAdd BLAST | 87 |
Sequence similaritiesi
Belongs to the mitochondrial carrier (TC 2.A.29) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_0_1 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
i Sequence
Sequence statusi: Complete.
Q4QDK0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSANNNSAAA PKKARQDMPK LGFWEEFMIS GVAAGAAKTA AAPIERVKLL
60 70 80 90 100
VQNQGEMIKQ GTLDRPYSGV MNCLTRTVKT EGLYALWRGN LSNVIRYFPT
110 120 130 140 150
QALNFAFKDQ FKRMFNYKKD RDGYMKWFMG NMASGGLAGA VSLCFVYSLD
160 170 180 190 200
YVRTRLANDT KSAKKGGERQ YSGMVDCYIK TFKTDGLVGL YRGFCVSCVG
210 220 230 240 250
IVAYRGFYFG LYDTLQPMLP VNNFIVNFML GWVVTIVSGL ISYPLDTVRR
260 270 280 290 300
RMMMTSGTGK NYRNSLECFM QCVKNEGAAS LFRGAGANIL RGVAGALVLS
310
GVDAIKPYYI SARAAKN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY691195 mRNA Translation: AAU00712.1 FR796415 Genomic DNA Translation: CAJ07105.1 FR796415 Genomic DNA Translation: CAJ07106.1 |
RefSeqi | XP_001682597.1, XM_001682545.1 XP_001682598.1, XM_001682546.1 |
Genome annotation databases
EnsemblProtistsi | CAJ07105; CAJ07105; LMJF_19_0200 CAJ07106; CAJ07106; LMJF_19_0210 |
GeneDBi | LmjF.19.0200:pep LmjF.19.0210:pep |
GeneIDi | 5651119 5651120 |
KEGGi | lma:LMJF_19_0200 lma:LMJF_19_0210 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY691195 mRNA Translation: AAU00712.1 FR796415 Genomic DNA Translation: CAJ07105.1 FR796415 Genomic DNA Translation: CAJ07106.1 |
RefSeqi | XP_001682597.1, XM_001682545.1 XP_001682598.1, XM_001682546.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 5664.LmjF.19.0210 |
Genome annotation databases
EnsemblProtistsi | CAJ07105; CAJ07105; LMJF_19_0200 CAJ07106; CAJ07106; LMJF_19_0210 |
GeneDBi | LmjF.19.0200:pep LmjF.19.0210:pep |
GeneIDi | 5651119 5651120 |
KEGGi | lma:LMJF_19_0200 lma:LMJF_19_0210 |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmjF.19.0200 TriTrypDB:LmjF.19.0210 |
Phylogenomic databases
eggNOGi | KOG0749, Eukaryota |
HOGENOMi | CLU_015166_12_0_1 |
Family and domain databases
Gene3Di | 1.50.40.10, 1 hit |
InterProi | View protein in InterPro IPR002113, ADT_euk_type IPR002067, Mit_carrier IPR018108, Mitochondrial_sb/sol_carrier IPR023395, Mt_carrier_dom_sf |
PANTHERi | PTHR45635, PTHR45635, 1 hit |
Pfami | View protein in Pfam PF00153, Mito_carr, 3 hits |
PRINTSi | PR00927, ADPTRNSLCASE PR00926, MITOCARRIER |
SUPFAMi | SSF103506, SSF103506, 1 hit |
PROSITEi | View protein in PROSITE PS50920, SOLCAR, 3 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q4QDK0_LEIMA | |
Accessioni | Q4QDK0Primary (citable) accession number: Q4QDK0 Secondary accession number(s): Q68H94 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | April 5, 2011 |
Last sequence update: | April 5, 2011 | |
Last modified: | February 10, 2021 | |
This is version 69 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |