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Entry version 109 (19 Jan 2022)
Sequence version 1 (19 Jul 2005)
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Protein
Submitted name:

Putative dynein heavy chain, cytosolic

Gene

LMJF_22_1110

Organism
Leishmania major
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor proteinARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...
BRENDAi
5.6.1.2, 2950

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative dynein heavy chain, cytosolicImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LMJF_22_1110Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLeishmania majorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5664 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaDiscobaEuglenozoaKinetoplasteaMetakinetoplastinaTrypanosomatidaTrypanosomatidaeLeishmaniinaeLeishmania
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000542 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
TriTrypDB:LmjF.22.1110
TriTrypDB:LMJLV39_220016600
TriTrypDB:LMJSD75_220016800

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation, DyneinARBA annotation, MicrotubuleARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5664.LmjF.22.1110

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2422 – 2565AAAInterPro annotationAdd BLAST144
Domaini2721 – 2960AAAInterPro annotationAdd BLAST240
Domaini3259 – 3408AAAInterPro annotationAdd BLAST150
Domaini3605 – 3843AAAInterPro annotationAdd BLAST239

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni128 – 155DisorderedSequence analysisAdd BLAST28
Regioni668 – 688DisorderedSequence analysisAdd BLAST21
Regioni1166 – 1187DisorderedSequence analysisAdd BLAST22
Regioni2246 – 2265DisorderedSequence analysisAdd BLAST20
Regioni3724 – 3773DisorderedSequence analysisAdd BLAST50
Regioni4697 – 4723DisorderedSequence analysisAdd BLAST27
Regioni5474 – 5495DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1267 – 1287Sequence analysisAdd BLAST21
Coiled coili1705 – 1725Sequence analysisAdd BLAST21
Coiled coili1988 – 2008Sequence analysisAdd BLAST21
Coiled coili3949 – 3986Sequence analysisAdd BLAST38
Coiled coili3991 – 4025Sequence analysisAdd BLAST35
Coiled coili4174 – 4243Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1166 – 1184Polar residuesSequence analysisAdd BLAST19
Compositional biasi4701 – 4723Polar residuesSequence analysisAdd BLAST23
Compositional biasi5479 – 5495Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3595, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_000038_7_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q4QBN6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...
PANTHERi
PTHR10676, PTHR10676, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 2 hits
PF12781, AAA_9, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4QBN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFPFDDNVVQ FIVLLTQHGT VEKVRAAIAQ SADAMGFASP PASPESAMHL
60 70 80 90 100
AAVQQQNIGE RDRGDDRETG VVSKTALLGA HVPLIAICEI SDGCAVTDGS
110 120 130 140 150
QIIATADPAT FFRSVSCMED ATPEEAVSLG APACGGTGAR RSTGSGPGDD
160 170 180 190 200
SVPGARHKAK ALSCILLERR DPHGAGGGTA GGGGARALSV RDLYIQSMDL
210 220 230 240 250
QRPLHTLQSI LRNIYDPMLR SHKTQSALRS HVQDLLSSIR SMHNVLPEID
260 270 280 290 300
VTRYVHEDLL QLCDANPLLD VPQLIDRLGE VAKDPSFIRR VLQARNRCRE
310 320 330 340 350
ALSMEPLLSG KLEEEELAKE LQSTNSKAIG APAVGPTGLP SGWSGVHPQP
360 370 380 390 400
SAFATPLPGA AAGIAYDGDG GDDSARVVQE RIVYWRCVHA WMEDILRQLR
410 420 430 440 450
GREWRLVHRL LAQRVETDYV GEYVGYLKLV QEYITFLNTI PEKRLVNVQD
460 470 480 490 500
MKEFNDVTDE IIMAATQPTR FAARLQLSLL TSLVWQISSR WVSVMETQQV
510 520 530 540 550
LSLDEDPNVA PVAAAGDANA TQHSADVTAG AHADPFVHLQ TLRIAIHSLR
560 570 580 590 600
TLQARYVEHS TQLRHQIRVV RSPREHVEHP RVEALLARCL AVRDLIEEHL
610 620 630 640 650
LLMRQLGVVF STKIRLQFAR AKRDAVPAMG VVAAQQQPGE EYALVMQDAF
660 670 680 690 700
NECVRAVGGW VDDAEDLQRS RKGSVGEPAA SSGSPHRGCK RCSNYLWQTS
710 720 730 740 750
PTAVQRFNAA VQEYQHKRSQ CDEQIALVVS QLLSNQQYAH SDGRSSMGGA
760 770 780 790 800
GAVGMAGAGA ALKGPQASVN YADNHGLRLF RTFKRFKMLP LERVQRVVHS
810 820 830 840 850
YQDAVAEKLS AYVGYVQDCY VNVPLTKKEV SYNMARFSVS ALVAQIMWEQ
860 870 880 890 900
RLAEALTKSM MRFDYVSEHG WHQLLYLRNV EHYWRLNASL AEFIGVPLDL
910 920 930 940 950
LVCDELQLDS EVHGCAVALA CLSLHYTEEA SEWEQDEHLR IAQDLVATCD
960 970 980 990 1000
PGALAVARDR MLIGGAPRLY KTTARARDIR SSRDIIQQRI ESHMASWFEE
1010 1020 1030 1040 1050
VDKLIGGSGL DQQTLLLSGP VLWAVNCGPF SGPHNTTGGA VANEADSAVM
1060 1070 1080 1090 1100
RLQPSGGAGA MTGGFTANAN YFNTGGAGSM PRASSFSPSS LALLRAQGRS
1110 1120 1130 1140 1150
ASPSVRRASF LVPVGSGDSE SLAPAAATAA SWMVEVAFPW SFPNIAEDLR
1160 1170 1180 1190 1200
YLESSYLTST LLSAGSGEPA ATSRNSSSAA GTTLSPRGRC PAVASDLAFL
1210 1220 1230 1240 1250
RDALRGNELR SRLAHTLVEL IHVYYVTVKG EDTSLVLLAT DEYQEVNRLF
1260 1270 1280 1290 1300
QMGIALRWSD EGLLSYVQQL SDTMQAFTTT VQQLRSKTEL VYRKIRAFLV
1310 1320 1330 1340 1350
RAFHPEAILQ RVKALRRIVD TLALRCVHAH LWTRQIQPLL EQALLTQMKY
1360 1370 1380 1390 1400
LMHSFTEDFL SMRSDVRFLE KGAETDVFRL TPLRVRMRVV YKEVRLESCC
1410 1420 1430 1440 1450
GAWRQHWISE LNRFFSWIDV LPRLYKEEET QADVVGVPAA LGSDMTSTAV
1460 1470 1480 1490 1500
THGSNSTDGA GVNAGIGRAG NNGHNAASGR APDDGYQYLL LRLPASALAE
1510 1520 1530 1540 1550
PLHAIEQCVQ DAIDTENEWR RGQQFLSMDV ALMQQRFGRD LRRWSHALRL
1560 1570 1580 1590 1600
MHTVTSRIMD YTQPNKLLGG IVILAQEAQI ELGRKLDQVS QYAHAKFKDL
1610 1620 1630 1640 1650
LQGEQERAFS VITQEQMKID ALDVISNAKD AAAFLSEAPR LKSELQKLDG
1660 1670 1680 1690 1700
EITLMDNGEV SLQKLGHVFP ENWMYAAALR EEYTSLAELV DRKLKAVQVR
1710 1720 1730 1740 1750
RPFLIEEAKS AASALEVKVA EVDARFHNVD SIAVSKEAPV LAKQMVSDIY
1760 1770 1780 1790 1800
DEAVAFSVEA KQVTAIQEAL GESPHVFASL QKLLADVARV KDVWGHVASA
1810 1820 1830 1840 1850
YVELNELGAV PFFEMVPRRL HERLQQIDEE TDAYQETMQS YQLYQNLKQK
1860 1870 1880 1890 1900
LCRVLSYNRL MQDLRSDAMS PLERSMRHWK TLQHKLRAPW VLASLTVANI
1910 1920 1930 1940 1950
WESDPGVNAA VYSEVVETAQ GERRIEVQLH NINNYWNMFE FSVVVYKKHV
1960 1970 1980 1990 2000
ALIRGWDEVF ERLTEDLSTF GGMRASPYFV FPQLVSMAND AEARLDRLRQ
2010 2020 2030 2040 2050
VLEVLLEVQK RWVYLDGILS ENAEVRVQLP HDTVKFDRTS RELLHILPRP
2060 2070 2080 2090 2100
RSSGNLPELH VSFFLEDEKL KATLERLLSQ LSAVQRALTS YLDTQRSRFP
2110 2120 2130 2140 2150
RFFFAGDDDL LEIMGNSKNP LFLNKHLKKM FTALASLQLD GNVKDATTRL
2160 2170 2180 2190 2200
CGFSSAEGEE LSFQPGPIAY RQRPIHEWLG EAEQGMVHTL REATLRAYNE
2210 2220 2230 2240 2250
LVSTKDASPY ALLWSMDWMR QKPTQVVCLA LQLLWTREQE SLLTGAHGGG
2260 2270 2280 2290 2300
AGATDARRTS QASSSTLSVV TSSMDDLLTR LAGNVLGNAV APSSRRQCEQ
2310 2320 2330 2340 2350
LITVAVYQRD VSRTLAARKV ASRDDFNWLS VLRLYVVPIH HQQQHGGKSM
2360 2370 2380 2390 2400
SSLSNIGLAR GTNVSGLVLS EYRSAETLEC RMADASVLHG FEYIGAYERL
2410 2420 2430 2440 2450
VQTPLTDKCY LTLMQSLHTR LGGSPVGPAG TGKTETVKAL GMQLGRHVLV
2460 2470 2480 2490 2500
FNCDDTFDYQ AVSRIFLGLC QVGAWGCFDE FNRLEERILS ALSLQIQVIQ
2510 2520 2530 2540 2550
HSLRAWQREV QLNHRAVPLH SNVAIFITMN PGYAGRSKLP GNLKQLFRTV
2560 2570 2580 2590 2600
TMTIPDRETI AEVMLFAQGF TTAEALSQKV VPLFRLCEEQ FTRQAHYDFG
2610 2620 2630 2640 2650
LRALKSVLVA AGDRKRQVAA ASRGSPGGHN AAGGAGADTV QETERTLLLE
2660 2670 2680 2690 2700
SIIATVAPKL VAQDAALFYP LLHDFFPGCS LPALPMDELR EAVECVCAES
2710 2720 2730 2740 2750
GLSPAAGWME KVLQFYHTKM TRHGVMIVGP SGTGKTTAWK VLMAAMVRLQ
2760 2770 2780 2790 2800
RALHMHAYVL SPKVLSKGEL FGTLDVTTRE WRDGVFTSIL RKIIDAEEQQ
2810 2820 2830 2840 2850
QIPADLALAG DDDTGHQVVA AQSVGVDNKK RASLKQNVIC DGDASAPGAQ
2860 2870 2880 2890 2900
SSEARKEHWI IFDGDVDPEW VENLNSVLDD NRLLTLPNGE RLPLPRSVRI
2910 2920 2930 2940 2950
IFEVQDLLYA TPATVSRCGM LWLSEGVVPL SGVLAHTYHQ LQEHPIVDAR
2960 2970 2980 2990 3000
GRHLHWGTDH MIGVTGVRSA FYTECLVTGE YGKVYHELVL SSARTSVEEV
3010 3020 3030 3040 3050
MAGSLPRHHG RTSSGDEDIT ALATPKRSSH LCKDATPQSD KAAELDMGDT
3060 3070 3080 3090 3100
LYGTTGHGSH AIFTSTSGGG AASTLRRSHP DAERIQELMV SSWAAAFEKD
3110 3120 3130 3140 3150
GAVVRGLQLM KSAAFRDVCV MVPSDQQCIQ SMVAFLVQGV WRTFETEQQS
3160 3170 3180 3190 3200
NGDVFSDAVV KKIAMQVLSY AIFWGLASAM SLENRMKLAQ QLGLRPTVDG
3210 3220 3230 3240 3250
VAQSMLEVEV CYRTGEWRLI RNRVKEISLL AEQVGANDTV ITTVDTCRHE
3260 3270 3280 3290 3300
DVLSAWLGAG RSAILCGPPG SGKTMSITAV LSSLPEYEVV FLNFSSGTTV
3310 3320 3330 3340 3350
KTIVKALEQH CRVQDTARGL VMAPTSGKQL LLFCDEVNLP ALDRYGTQVV
3360 3370 3380 3390 3400
VQLLRQLIER NGFYRARDNT WITVEDVQVV GACNPPTDPG RVSLSARFLR
3410 3420 3430 3440 3450
WAPVLLVDFP SPESLKTIYT TYCRAILAWN ERLSGQVATR LAQAMVKMYR
3460 3470 3480 3490 3500
VSQAKFTPIQ QPHYLYSPRE LSRWSRALYE GILTWDDAVR RQLNVSQLVR
3510 3520 3530 3540 3550
LAVHEGLRVF ADRLVTAEER AWTDTAIVEA FREFFTDVDD HAFHQPLLYS
3560 3570 3580 3590 3600
TLLSRSYTDS PREELRAYVQ KKLAAFNEEE SLGNLVIYDA MIDHVVRIDR
3610 3620 3630 3640 3650
VLRQPLGHLL IAGSSGVGKT ALTKLVAWMR GFSTFTLMLH RGYDLDDFEH
3660 3670 3680 3690 3700
DLRGVLRRAG CKRERICFLF DESNILQPSF LEYMNALLAS GEVPGLFDGD
3710 3720 3730 3740 3750
EWSKLMQEVR DAVLASQSYY ATSRSAGGAG AAGRAGGSAG GGGEAGRDRD
3760 3770 3780 3790 3800
SSALRGGGCK GLDGNDNGNG VTGSQRASVV TGVGVAASAA GDDLVDVHNE
3810 3820 3830 3840 3850
AELYHWFLRN VHEYLHVVLT INPSSGEFTS RTVASPALVN RCTIDWFGDW
3860 3870 3880 3890 3900
DTTTLQQVCQ ERIRHLALLP ACHGVFAIEV EAKEAVVESL CAIHVATQHI
3910 3920 3930 3940 3950
NQALRVRYAN QGTFVTPRHF TDCVSHFVTI FQEKRKVSSD ALVHLHSGLK
3960 3970 3980 3990 4000
KLELTAQEVA AQRATLQDNE AEIEASSRRA QAMLERIVSE TDVAKREKAA
4010 4020 4030 4040 4050
AQDLERQLQD EHAQISEDAQ RLSIELAEAE PALREADAAL STVKPEYLRE
4060 4070 4080 4090 4100
IRAYAMPPPM VKRTLEAVGA LMGEKNCEDW DSLKNCIRRD DFLASVRNFR
4110 4120 4130 4140 4150
PDDITEPARE RVRGMMRDSK FTVEAAYRAS KAAGPLMQWV FFQVKYSAIY
4160 4170 4180 4190 4200
QRVAPVRSKI EKLIKARDVK LKGLEVAQEE VREKENSLQQ LMGEYQNATA
4210 4220 4230 4240 4250
QIAELKQRIT AISAKCNRAQ TVLQQLLDER DRWEKEVHSF DSEARTTLGD
4260 4270 4280 4290 4300
CVMSAVFLAY TGFYDEHTRE RVLMPRWLAC LQRATIPVRK GLSVTEYLSP
4310 4320 4330 4340 4350
ATQQLAWEEA GLPKDRLNID NAVIMHRCQR YVLLIDPTDV AAHFVLRYYG
4360 4370 4380 4390 4400
AQKITKTSFS RPGYVKQLEM AVRFGYPILM EDAEHLDPAV VPLLNGEVRC
4410 4420 4430 4440 4450
HGTRHITRIG PHEVDLAPSF HLFLHTRNPN FQSPPDLAGQ VCMVNFTVTL
4460 4470 4480 4490 4500
SSLQSQCLHY TLLHERPDVD AKRSNLLKAQ GEYQLRLRVL EDKLLTRIAE
4510 4520 4530 4540 4550
AEGSLLDNNA LIESLTELKE EATCIAGDIA DSENSMREIR SVEDMYRPIA
4560 4570 4580 4590 4600
TVVAQAHFAL QRFEELSPYY CYNVRFVLRV LDDALRALPA TSTPAADGGL
4610 4620 4630 4640 4650
RLQQLTYGIF VLLHRRVVRG MFHEDHLVWA LRLAQLRSAM SATGAKSASS
4660 4670 4680 4690 4700
APTAASMVVL PTDSTGGSAV MPEEWEWILS CLRLAGSGVG AAGAGAGLPS
4710 4720 4730 4740 4750
TAASRTMTTD SSEDGGASSP ITAATTATSL PPVVRQACPA LGLQSCQALA
4760 4770 4780 4790 4800
FLLTKPAFNE VRETLTTRAP AWEAVLTSAT PVATSESALP PECFPRGASR
4810 4820 4830 4840 4850
VRRFLLLALI LLNTRRDAFI EAVRQLLASY FSPKEMGTAA AAGTDAAAAL
4860 4870 4880 4890 4900
FTDDLFAPQT NDLADGIMAE LSAATPLLMV ADTMFDPALR VEELAQRTCT
4910 4920 4930 4940 4950
NLSVVAMGSM ESIENADAYL AEATKSGGWV LLKNVHLARG YMDKLEKQLH
4960 4970 4980 4990 5000
FQRSEGQLHK EFRLFLTAER DRSAAKPSTT ATAAAASSKV LPINLIEASV
5010 5020 5030 5040 5050
VVVYEAPPGM QSSLLQTYGE YPVVGAAAFD GTDASSVAPS AGAAAASNNT
5060 5070 5080 5090 5100
SLQRLYLAAA WLHSVITERI LYKPLGWSEA YEYTEVEYQR VVQAVQAWSS
5110 5120 5130 5140 5150
AAPAPAAATA SSSNASALKV SWDALRTIVA TTVYGGKVSN VFDQHILNVF
5160 5170 5180 5190 5200
CRRLLRPEML QDAAQFVSEA AAAGAPPPPI RGRSRAELLQ WIHALPGGSS
5210 5220 5230 5240 5250
HPAWLALPIG ADRMTRARSA IEVVERLSLV QSTLDDELTF AEIDSDAQAA
5260 5270 5280 5290 5300
ASGALRATRW AAKVQSYCTA WYPILRDALG KLEKHPFVLQ AVALHKQETV
5310 5320 5330 5340 5350
ERASAADVGA AKESGVNRSG ASHSGGVSAP LVLAMQREVV AAVELVRHLL
5360 5370 5380 5390 5400
TCVRELREVA MEERTPSSVH RGLVEELMKD HVPDVWAAHL RGVHGSAAHS
5410 5420 5430 5440 5450
LFVGLWIADV QQRVEHLLEL ATAAHGGQLA KTPVRLGALF SPGAFLTAFK
5460 5470 5480 5490 5500
QHCARAEQVP LEQLVPQVEV DAATGASAGR APRTTSSALS TTGIPGAPAT
5510 5520 5530 5540 5550
SAASLAPLRE NEVVFTGLTL HSAQVGVAGK CTLRGATTSG AAPALSSAVV
5560 5570 5580 5590 5600
LRWRWVRSTD SVATTTALTA RLERQTDQQQ SILLPFYTTE NREALLEVLE
5610 5620 5630
LPKAPNSGIT SGDGDAGVHA WYERGVCVTA WSASE
Length:5,635
Mass (Da):620,071
Last modified:July 19, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64A9EB81A9B14641
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
FR796418 Genomic DNA Translation: CAJ04513.1

NCBI Reference Sequences

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RefSeqi
XP_001683262.1, XM_001683210.1

Genome annotation databases

Ensembl protists genome annotation project

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EnsemblProtistsi
CAJ04513; CAJ04513; LMJF_22_1110

Database of genes from NCBI RefSeq genomes

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GeneIDi
5651870

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
lma:LMJF_22_1110

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796418 Genomic DNA Translation: CAJ04513.1
RefSeqiXP_001683262.1, XM_001683210.1

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5664.LmjF.22.1110

Genome annotation databases

EnsemblProtistsiCAJ04513; CAJ04513; LMJF_22_1110
GeneIDi5651870
KEGGilma:LMJF_22_1110

Organism-specific databases

VEuPathDBiTriTrypDB:LmjF.22.1110
TriTrypDB:LMJLV39_220016600
TriTrypDB:LMJSD75_220016800

Phylogenomic databases

eggNOGiKOG3595, Eukaryota
HOGENOMiCLU_000038_7_0_1
InParanoidiQ4QBN6

Enzyme and pathway databases

BRENDAi5.6.1.2, 2950

Family and domain databases

Gene3Di1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase
PANTHERiPTHR10676, PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 2 hits
PF12781, AAA_9, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 4 hits
SUPFAMiSSF52540, SSF52540, 4 hits

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4QBN6_LEIMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4QBN6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: January 19, 2022
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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