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UniProtKB - Q4QBN6 (Q4QBN6_LEIMA)

Entry version 109 (19 Jan 2022)
Sequence version 1 (19 Jul 2005)
Previous versions | rss
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Protein
Submitted name:

Putative dynein heavy chain, cytosolic

Gene

LMJF_22_1110

Organism
Leishmania major
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMotor proteinARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDA Comprehensive Enzyme Information System

More...BRENDAi		5.6.1.2, 2950

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Putative dynein heavy chain, cytosolicImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LMJF_22_1110Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLeishmania majorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5664 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000542 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

Organism-specific databases

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		TriTrypDB:LmjF.22.1110
TriTrypDB:LMJLV39_220016600
TriTrypDB:LMJSD75_220016800

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, CytoskeletonARBA annotation, DyneinARBA annotation, MicrotubuleARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

STRING: functional protein association networks

More...STRINGi		5664.LmjF.22.1110

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2422 – 2565AAAInterPro annotationAdd BLAST144
Domaini2721 – 2960AAAInterPro annotationAdd BLAST240
Domaini3259 – 3408AAAInterPro annotationAdd BLAST150
Domaini3605 – 3843AAAInterPro annotationAdd BLAST239

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni128 – 155DisorderedSequence analysisAdd BLAST28
Regioni668 – 688DisorderedSequence analysisAdd BLAST21
Regioni1166 – 1187DisorderedSequence analysisAdd BLAST22
Regioni2246 – 2265DisorderedSequence analysisAdd BLAST20
Regioni3724 – 3773DisorderedSequence analysisAdd BLAST50
Regioni4697 – 4723DisorderedSequence analysisAdd BLAST27
Regioni5474 – 5495DisorderedSequence analysisAdd BLAST22

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1267 – 1287Sequence analysisAdd BLAST21
Coiled coili1705 – 1725Sequence analysisAdd BLAST21
Coiled coili1988 – 2008Sequence analysisAdd BLAST21
Coiled coili3949 – 3986Sequence analysisAdd BLAST38
Coiled coili3991 – 4025Sequence analysisAdd BLAST35
Coiled coili4174 – 4243Sequence analysisAdd BLAST70

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1166 – 1184Polar residuesSequence analysisAdd BLAST19
Compositional biasi4701 – 4723Polar residuesSequence analysisAdd BLAST23
Compositional biasi5479 – 5495Polar residuesSequence analysisAdd BLAST17

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the dynein heavy chain family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG3595, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_000038_7_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q4QBN6

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase

The PANTHER Classification System

More...PANTHERi		PTHR10676, PTHR10676, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 2 hits
PF12781, AAA_9, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00382, AAA, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF52540, SSF52540, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4QBN6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFPFDDNVVQ FIVLLTQHGT VEKVRAAIAQ SADAMGFASP PASPESAMHL 
        60         70         80         90        100
AAVQQQNIGE RDRGDDRETG VVSKTALLGA HVPLIAICEI SDGCAVTDGS 
       110        120        130        140        150
QIIATADPAT FFRSVSCMED ATPEEAVSLG APACGGTGAR RSTGSGPGDD 
       160        170        180        190        200
SVPGARHKAK ALSCILLERR DPHGAGGGTA GGGGARALSV RDLYIQSMDL 
       210        220        230        240        250
QRPLHTLQSI LRNIYDPMLR SHKTQSALRS HVQDLLSSIR SMHNVLPEID 
       260        270        280        290        300
VTRYVHEDLL QLCDANPLLD VPQLIDRLGE VAKDPSFIRR VLQARNRCRE 
       310        320        330        340        350
ALSMEPLLSG KLEEEELAKE LQSTNSKAIG APAVGPTGLP SGWSGVHPQP 
       360        370        380        390        400
SAFATPLPGA AAGIAYDGDG GDDSARVVQE RIVYWRCVHA WMEDILRQLR 
       410        420        430        440        450
GREWRLVHRL LAQRVETDYV GEYVGYLKLV QEYITFLNTI PEKRLVNVQD 
       460        470        480        490        500
MKEFNDVTDE IIMAATQPTR FAARLQLSLL TSLVWQISSR WVSVMETQQV 
       510        520        530        540        550
LSLDEDPNVA PVAAAGDANA TQHSADVTAG AHADPFVHLQ TLRIAIHSLR 
       560        570        580        590        600
TLQARYVEHS TQLRHQIRVV RSPREHVEHP RVEALLARCL AVRDLIEEHL 
       610        620        630        640        650
LLMRQLGVVF STKIRLQFAR AKRDAVPAMG VVAAQQQPGE EYALVMQDAF 
       660        670        680        690        700
NECVRAVGGW VDDAEDLQRS RKGSVGEPAA SSGSPHRGCK RCSNYLWQTS 
       710        720        730        740        750
PTAVQRFNAA VQEYQHKRSQ CDEQIALVVS QLLSNQQYAH SDGRSSMGGA 
       760        770        780        790        800
GAVGMAGAGA ALKGPQASVN YADNHGLRLF RTFKRFKMLP LERVQRVVHS 
       810        820        830        840        850
YQDAVAEKLS AYVGYVQDCY VNVPLTKKEV SYNMARFSVS ALVAQIMWEQ 
       860        870        880        890        900
RLAEALTKSM MRFDYVSEHG WHQLLYLRNV EHYWRLNASL AEFIGVPLDL 
       910        920        930        940        950
LVCDELQLDS EVHGCAVALA CLSLHYTEEA SEWEQDEHLR IAQDLVATCD 
       960        970        980        990       1000
PGALAVARDR MLIGGAPRLY KTTARARDIR SSRDIIQQRI ESHMASWFEE 
      1010       1020       1030       1040       1050
VDKLIGGSGL DQQTLLLSGP VLWAVNCGPF SGPHNTTGGA VANEADSAVM 
      1060       1070       1080       1090       1100
RLQPSGGAGA MTGGFTANAN YFNTGGAGSM PRASSFSPSS LALLRAQGRS 
      1110       1120       1130       1140       1150
ASPSVRRASF LVPVGSGDSE SLAPAAATAA SWMVEVAFPW SFPNIAEDLR 
      1160       1170       1180       1190       1200
YLESSYLTST LLSAGSGEPA ATSRNSSSAA GTTLSPRGRC PAVASDLAFL 
      1210       1220       1230       1240       1250
RDALRGNELR SRLAHTLVEL IHVYYVTVKG EDTSLVLLAT DEYQEVNRLF 
      1260       1270       1280       1290       1300
QMGIALRWSD EGLLSYVQQL SDTMQAFTTT VQQLRSKTEL VYRKIRAFLV 
      1310       1320       1330       1340       1350
RAFHPEAILQ RVKALRRIVD TLALRCVHAH LWTRQIQPLL EQALLTQMKY 
      1360       1370       1380       1390       1400
LMHSFTEDFL SMRSDVRFLE KGAETDVFRL TPLRVRMRVV YKEVRLESCC 
      1410       1420       1430       1440       1450
GAWRQHWISE LNRFFSWIDV LPRLYKEEET QADVVGVPAA LGSDMTSTAV 
      1460       1470       1480       1490       1500
THGSNSTDGA GVNAGIGRAG NNGHNAASGR APDDGYQYLL LRLPASALAE 
      1510       1520       1530       1540       1550
PLHAIEQCVQ DAIDTENEWR RGQQFLSMDV ALMQQRFGRD LRRWSHALRL 
      1560       1570       1580       1590       1600
MHTVTSRIMD YTQPNKLLGG IVILAQEAQI ELGRKLDQVS QYAHAKFKDL 
      1610       1620       1630       1640       1650
LQGEQERAFS VITQEQMKID ALDVISNAKD AAAFLSEAPR LKSELQKLDG 
      1660       1670       1680       1690       1700
EITLMDNGEV SLQKLGHVFP ENWMYAAALR EEYTSLAELV DRKLKAVQVR 
      1710       1720       1730       1740       1750
RPFLIEEAKS AASALEVKVA EVDARFHNVD SIAVSKEAPV LAKQMVSDIY 
      1760       1770       1780       1790       1800
DEAVAFSVEA KQVTAIQEAL GESPHVFASL QKLLADVARV KDVWGHVASA 
      1810       1820       1830       1840       1850
YVELNELGAV PFFEMVPRRL HERLQQIDEE TDAYQETMQS YQLYQNLKQK 
      1860       1870       1880       1890       1900
LCRVLSYNRL MQDLRSDAMS PLERSMRHWK TLQHKLRAPW VLASLTVANI 
      1910       1920       1930       1940       1950
WESDPGVNAA VYSEVVETAQ GERRIEVQLH NINNYWNMFE FSVVVYKKHV 
      1960       1970       1980       1990       2000
ALIRGWDEVF ERLTEDLSTF GGMRASPYFV FPQLVSMAND AEARLDRLRQ 
      2010       2020       2030       2040       2050
VLEVLLEVQK RWVYLDGILS ENAEVRVQLP HDTVKFDRTS RELLHILPRP 
      2060       2070       2080       2090       2100
RSSGNLPELH VSFFLEDEKL KATLERLLSQ LSAVQRALTS YLDTQRSRFP 
      2110       2120       2130       2140       2150
RFFFAGDDDL LEIMGNSKNP LFLNKHLKKM FTALASLQLD GNVKDATTRL 
      2160       2170       2180       2190       2200
CGFSSAEGEE LSFQPGPIAY RQRPIHEWLG EAEQGMVHTL REATLRAYNE 
      2210       2220       2230       2240       2250
LVSTKDASPY ALLWSMDWMR QKPTQVVCLA LQLLWTREQE SLLTGAHGGG 
      2260       2270       2280       2290       2300
AGATDARRTS QASSSTLSVV TSSMDDLLTR LAGNVLGNAV APSSRRQCEQ 
      2310       2320       2330       2340       2350
LITVAVYQRD VSRTLAARKV ASRDDFNWLS VLRLYVVPIH HQQQHGGKSM 
      2360       2370       2380       2390       2400
SSLSNIGLAR GTNVSGLVLS EYRSAETLEC RMADASVLHG FEYIGAYERL 
      2410       2420       2430       2440       2450
VQTPLTDKCY LTLMQSLHTR LGGSPVGPAG TGKTETVKAL GMQLGRHVLV 
      2460       2470       2480       2490       2500
FNCDDTFDYQ AVSRIFLGLC QVGAWGCFDE FNRLEERILS ALSLQIQVIQ 
      2510       2520       2530       2540       2550
HSLRAWQREV QLNHRAVPLH SNVAIFITMN PGYAGRSKLP GNLKQLFRTV 
      2560       2570       2580       2590       2600
TMTIPDRETI AEVMLFAQGF TTAEALSQKV VPLFRLCEEQ FTRQAHYDFG 
      2610       2620       2630       2640       2650
LRALKSVLVA AGDRKRQVAA ASRGSPGGHN AAGGAGADTV QETERTLLLE 
      2660       2670       2680       2690       2700
SIIATVAPKL VAQDAALFYP LLHDFFPGCS LPALPMDELR EAVECVCAES 
      2710       2720       2730       2740       2750
GLSPAAGWME KVLQFYHTKM TRHGVMIVGP SGTGKTTAWK VLMAAMVRLQ 
      2760       2770       2780       2790       2800
RALHMHAYVL SPKVLSKGEL FGTLDVTTRE WRDGVFTSIL RKIIDAEEQQ 
      2810       2820       2830       2840       2850
QIPADLALAG DDDTGHQVVA AQSVGVDNKK RASLKQNVIC DGDASAPGAQ 
      2860       2870       2880       2890       2900
SSEARKEHWI IFDGDVDPEW VENLNSVLDD NRLLTLPNGE RLPLPRSVRI 
      2910       2920       2930       2940       2950
IFEVQDLLYA TPATVSRCGM LWLSEGVVPL SGVLAHTYHQ LQEHPIVDAR 
      2960       2970       2980       2990       3000
GRHLHWGTDH MIGVTGVRSA FYTECLVTGE YGKVYHELVL SSARTSVEEV 
      3010       3020       3030       3040       3050
MAGSLPRHHG RTSSGDEDIT ALATPKRSSH LCKDATPQSD KAAELDMGDT 
      3060       3070       3080       3090       3100
LYGTTGHGSH AIFTSTSGGG AASTLRRSHP DAERIQELMV SSWAAAFEKD 
      3110       3120       3130       3140       3150
GAVVRGLQLM KSAAFRDVCV MVPSDQQCIQ SMVAFLVQGV WRTFETEQQS 
      3160       3170       3180       3190       3200
NGDVFSDAVV KKIAMQVLSY AIFWGLASAM SLENRMKLAQ QLGLRPTVDG 
      3210       3220       3230       3240       3250
VAQSMLEVEV CYRTGEWRLI RNRVKEISLL AEQVGANDTV ITTVDTCRHE 
      3260       3270       3280       3290       3300
DVLSAWLGAG RSAILCGPPG SGKTMSITAV LSSLPEYEVV FLNFSSGTTV 
      3310       3320       3330       3340       3350
KTIVKALEQH CRVQDTARGL VMAPTSGKQL LLFCDEVNLP ALDRYGTQVV 
      3360       3370       3380       3390       3400
VQLLRQLIER NGFYRARDNT WITVEDVQVV GACNPPTDPG RVSLSARFLR 
      3410       3420       3430       3440       3450
WAPVLLVDFP SPESLKTIYT TYCRAILAWN ERLSGQVATR LAQAMVKMYR 
      3460       3470       3480       3490       3500
VSQAKFTPIQ QPHYLYSPRE LSRWSRALYE GILTWDDAVR RQLNVSQLVR 
      3510       3520       3530       3540       3550
LAVHEGLRVF ADRLVTAEER AWTDTAIVEA FREFFTDVDD HAFHQPLLYS 
      3560       3570       3580       3590       3600
TLLSRSYTDS PREELRAYVQ KKLAAFNEEE SLGNLVIYDA MIDHVVRIDR 
      3610       3620       3630       3640       3650
VLRQPLGHLL IAGSSGVGKT ALTKLVAWMR GFSTFTLMLH RGYDLDDFEH 
      3660       3670       3680       3690       3700
DLRGVLRRAG CKRERICFLF DESNILQPSF LEYMNALLAS GEVPGLFDGD 
      3710       3720       3730       3740       3750
EWSKLMQEVR DAVLASQSYY ATSRSAGGAG AAGRAGGSAG GGGEAGRDRD 
      3760       3770       3780       3790       3800
SSALRGGGCK GLDGNDNGNG VTGSQRASVV TGVGVAASAA GDDLVDVHNE 
      3810       3820       3830       3840       3850
AELYHWFLRN VHEYLHVVLT INPSSGEFTS RTVASPALVN RCTIDWFGDW 
      3860       3870       3880       3890       3900
DTTTLQQVCQ ERIRHLALLP ACHGVFAIEV EAKEAVVESL CAIHVATQHI 
      3910       3920       3930       3940       3950
NQALRVRYAN QGTFVTPRHF TDCVSHFVTI FQEKRKVSSD ALVHLHSGLK 
      3960       3970       3980       3990       4000
KLELTAQEVA AQRATLQDNE AEIEASSRRA QAMLERIVSE TDVAKREKAA 
      4010       4020       4030       4040       4050
AQDLERQLQD EHAQISEDAQ RLSIELAEAE PALREADAAL STVKPEYLRE 
      4060       4070       4080       4090       4100
IRAYAMPPPM VKRTLEAVGA LMGEKNCEDW DSLKNCIRRD DFLASVRNFR 
      4110       4120       4130       4140       4150
PDDITEPARE RVRGMMRDSK FTVEAAYRAS KAAGPLMQWV FFQVKYSAIY 
      4160       4170       4180       4190       4200
QRVAPVRSKI EKLIKARDVK LKGLEVAQEE VREKENSLQQ LMGEYQNATA 
      4210       4220       4230       4240       4250
QIAELKQRIT AISAKCNRAQ TVLQQLLDER DRWEKEVHSF DSEARTTLGD 
      4260       4270       4280       4290       4300
CVMSAVFLAY TGFYDEHTRE RVLMPRWLAC LQRATIPVRK GLSVTEYLSP 
      4310       4320       4330       4340       4350
ATQQLAWEEA GLPKDRLNID NAVIMHRCQR YVLLIDPTDV AAHFVLRYYG 
      4360       4370       4380       4390       4400
AQKITKTSFS RPGYVKQLEM AVRFGYPILM EDAEHLDPAV VPLLNGEVRC 
      4410       4420       4430       4440       4450
HGTRHITRIG PHEVDLAPSF HLFLHTRNPN FQSPPDLAGQ VCMVNFTVTL 
      4460       4470       4480       4490       4500
SSLQSQCLHY TLLHERPDVD AKRSNLLKAQ GEYQLRLRVL EDKLLTRIAE 
      4510       4520       4530       4540       4550
AEGSLLDNNA LIESLTELKE EATCIAGDIA DSENSMREIR SVEDMYRPIA 
      4560       4570       4580       4590       4600
TVVAQAHFAL QRFEELSPYY CYNVRFVLRV LDDALRALPA TSTPAADGGL 
      4610       4620       4630       4640       4650
RLQQLTYGIF VLLHRRVVRG MFHEDHLVWA LRLAQLRSAM SATGAKSASS 
      4660       4670       4680       4690       4700
APTAASMVVL PTDSTGGSAV MPEEWEWILS CLRLAGSGVG AAGAGAGLPS 
      4710       4720       4730       4740       4750
TAASRTMTTD SSEDGGASSP ITAATTATSL PPVVRQACPA LGLQSCQALA 
      4760       4770       4780       4790       4800
FLLTKPAFNE VRETLTTRAP AWEAVLTSAT PVATSESALP PECFPRGASR 
      4810       4820       4830       4840       4850
VRRFLLLALI LLNTRRDAFI EAVRQLLASY FSPKEMGTAA AAGTDAAAAL 
      4860       4870       4880       4890       4900
FTDDLFAPQT NDLADGIMAE LSAATPLLMV ADTMFDPALR VEELAQRTCT 
      4910       4920       4930       4940       4950
NLSVVAMGSM ESIENADAYL AEATKSGGWV LLKNVHLARG YMDKLEKQLH 
      4960       4970       4980       4990       5000
FQRSEGQLHK EFRLFLTAER DRSAAKPSTT ATAAAASSKV LPINLIEASV 
      5010       5020       5030       5040       5050
VVVYEAPPGM QSSLLQTYGE YPVVGAAAFD GTDASSVAPS AGAAAASNNT 
      5060       5070       5080       5090       5100
SLQRLYLAAA WLHSVITERI LYKPLGWSEA YEYTEVEYQR VVQAVQAWSS 
      5110       5120       5130       5140       5150
AAPAPAAATA SSSNASALKV SWDALRTIVA TTVYGGKVSN VFDQHILNVF 
      5160       5170       5180       5190       5200
CRRLLRPEML QDAAQFVSEA AAAGAPPPPI RGRSRAELLQ WIHALPGGSS 
      5210       5220       5230       5240       5250
HPAWLALPIG ADRMTRARSA IEVVERLSLV QSTLDDELTF AEIDSDAQAA 
      5260       5270       5280       5290       5300
ASGALRATRW AAKVQSYCTA WYPILRDALG KLEKHPFVLQ AVALHKQETV 
      5310       5320       5330       5340       5350
ERASAADVGA AKESGVNRSG ASHSGGVSAP LVLAMQREVV AAVELVRHLL 
      5360       5370       5380       5390       5400
TCVRELREVA MEERTPSSVH RGLVEELMKD HVPDVWAAHL RGVHGSAAHS 
      5410       5420       5430       5440       5450
LFVGLWIADV QQRVEHLLEL ATAAHGGQLA KTPVRLGALF SPGAFLTAFK 
      5460       5470       5480       5490       5500
QHCARAEQVP LEQLVPQVEV DAATGASAGR APRTTSSALS TTGIPGAPAT 
      5510       5520       5530       5540       5550
SAASLAPLRE NEVVFTGLTL HSAQVGVAGK CTLRGATTSG AAPALSSAVV 
      5560       5570       5580       5590       5600
LRWRWVRSTD SVATTTALTA RLERQTDQQQ SILLPFYTTE NREALLEVLE 
      5610       5620       5630 
LPKAPNSGIT SGDGDAGVHA WYERGVCVTA WSASE
Length:5,635
Mass (Da):620,071
Last modified:July 19, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i64A9EB81A9B14641
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
FR796418 Genomic DNA Translation: CAJ04513.1

NCBI Reference Sequences

More...RefSeqi		XP_001683262.1, XM_001683210.1

Genome annotation databases

Ensembl protists genome annotation project

More...EnsemblProtistsi		CAJ04513; CAJ04513; LMJF_22_1110

Database of genes from NCBI RefSeq genomes

More...GeneIDi		5651870

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		lma:LMJF_22_1110

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796418 Genomic DNA Translation: CAJ04513.1
RefSeqiXP_001683262.1, XM_001683210.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Protein-protein interaction databases

STRINGi5664.LmjF.22.1110

Genome annotation databases

EnsemblProtistsiCAJ04513; CAJ04513; LMJF_22_1110
GeneIDi5651870
KEGGilma:LMJF_22_1110

Organism-specific databases

VEuPathDBiTriTrypDB:LmjF.22.1110
TriTrypDB:LMJLV39_220016600
TriTrypDB:LMJSD75_220016800

Phylogenomic databases

eggNOGiKOG3595, Eukaryota
HOGENOMiCLU_000038_7_0_1
InParanoidiQ4QBN6

Enzyme and pathway databases

BRENDAi5.6.1.2, 2950

Family and domain databases

Gene3Di1.10.8.710, 1 hit
1.10.8.720, 1 hit
1.20.140.100, 1 hit
3.10.490.20, 1 hit
3.20.180.20, 1 hit
3.40.50.300, 6 hits
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR035699, AAA_6
IPR035706, AAA_9
IPR041658, AAA_lid_11
IPR042219, AAA_lid_11_sf
IPR026983, DHC_fam
IPR042222, Dynein_2_N
IPR043157, Dynein_AAA1S
IPR041228, Dynein_C
IPR043160, Dynein_C_barrel
IPR024743, Dynein_HC_stalk
IPR024317, Dynein_heavy_chain_D4_dom
IPR004273, Dynein_heavy_D6_P-loop
IPR013602, Dynein_heavy_linker
IPR042228, Dynein_linker_3
IPR027417, P-loop_NTPase
PANTHERiPTHR10676, PTHR10676, 1 hit
PfamiView protein in Pfam
PF12774, AAA_6, 1 hit
PF12780, AAA_8, 2 hits
PF12781, AAA_9, 1 hit
PF18198, AAA_lid_11, 1 hit
PF08393, DHC_N2, 1 hit
PF18199, Dynein_C, 1 hit
PF03028, Dynein_heavy, 1 hit
PF12777, MT, 1 hit
SMARTiView protein in SMART
SM00382, AAA, 4 hits
SUPFAMiSSF52540, SSF52540, 4 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4QBN6_LEIMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4QBN6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: January 19, 2022
This is version 109 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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