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Entry version 70 (17 Jun 2020)
Sequence version 1 (19 Jul 2005)
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Protein
Submitted name:

Uncharacterized protein

Gene

LMJF_30_1625

Organism
Leishmania major
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:LMJF_30_1625Imported, LMJF_30_1630Imported, LMJF_30_1635Imported, LMJF_30_1640Imported, LMJF_30_1645Imported, LMJF_30_1650Imported, LMJF_30_1660Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLeishmania majorImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5664 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaDiscobaEuglenozoaKinetoplasteaMetakinetoplastinaTrypanosomatidaTrypanosomatidaeLeishmaniinaeLeishmania
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000542 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 30

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
TriTrypDB:LmjF.30.1625
TriTrypDB:LmjF.30.1630
TriTrypDB:LmjF.30.1635
TriTrypDB:LmjF.30.1640
TriTrypDB:LmjF.30.1645
TriTrypDB:LmjF.30.1650
TriTrypDB:LmjF.30.1660

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei56 – 81HelicalSequence analysisAdd BLAST26
Transmembranei102 – 121HelicalSequence analysisAdd BLAST20

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
5664.LmjF.30.1660

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG3318 Eukaryota
ENOG41118KQ LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_098404_3_0_1

KEGG Orthology (KO)

More...
KOi
K23565

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009445 TMEM85/Emc4

The PANTHER Classification System

More...
PANTHERi
PTHR19315 PTHR19315, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF06417 DUF1077, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4Q7D8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASAVANVNA SAKPMTDKEI TRHRVMARLS EIRTQPLKQL PMTVFMMWMV
60 70 80 90 100
GNEVSIFSIM FVGMAVVNPL QSILSAGKLF ADFEEDSKAD RQIRSAVNQA
110 120 130 140 150
RWIYIGCCLV AFLVALVKLN WMELLPVSSM DWMDNTPPTY QELSSGVFYH
Length:150
Mass (Da):16,924
Last modified:July 19, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iAE084E2734677E32
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
FR796426 Genomic DNA Translation: CAJ06282.1
FR796426 Genomic DNA Translation: CAJ06285.1
FR796426 Genomic DNA Translation: CAJ06287.1
FR796426 Genomic DNA Translation: CAJ06289.1
FR796426 Genomic DNA Translation: CAJ06291.1
FR796426 Genomic DNA Translation: CAJ06293.1
FR796426 Genomic DNA Translation: CAJ06295.1

NCBI Reference Sequences

More...
RefSeqi
XP_001684758.1, XM_001684706.1
XP_001684760.1, XM_001684708.1
XP_001684762.1, XM_001684710.1
XP_001684764.1, XM_001684712.1
XP_001684766.1, XM_001684714.1
XP_001684768.1, XM_001684716.1
XP_001684770.1, XM_001684718.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAJ06282; CAJ06282; LMJF_30_1625
CAJ06285; CAJ06285; LMJF_30_1630
CAJ06287; CAJ06287; LMJF_30_1635
CAJ06289; CAJ06289; LMJF_30_1640
CAJ06291; CAJ06291; LMJF_30_1645
CAJ06293; CAJ06293; LMJF_30_1650
CAJ06295; CAJ06295; LMJF_30_1660

GeneDB pathogen genome database from Sanger Institute

More...
GeneDBi
LmjF.30.1625:pep
LmjF.30.1630:pep
LmjF.30.1635:pep
LmjF.30.1640:pep
LmjF.30.1645:pep
LmjF.30.1650:pep
LmjF.30.1660:pep

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
5653697
5653699
5653701
5653703
5653705
5653707
5653709

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
lma:LMJF_30_1625
lma:LMJF_30_1630
lma:LMJF_30_1635
lma:LMJF_30_1640
lma:LMJF_30_1645
lma:LMJF_30_1650
lma:LMJF_30_1660

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
FR796426 Genomic DNA Translation: CAJ06282.1
FR796426 Genomic DNA Translation: CAJ06285.1
FR796426 Genomic DNA Translation: CAJ06287.1
FR796426 Genomic DNA Translation: CAJ06289.1
FR796426 Genomic DNA Translation: CAJ06291.1
FR796426 Genomic DNA Translation: CAJ06293.1
FR796426 Genomic DNA Translation: CAJ06295.1
RefSeqiXP_001684758.1, XM_001684706.1
XP_001684760.1, XM_001684708.1
XP_001684762.1, XM_001684710.1
XP_001684764.1, XM_001684712.1
XP_001684766.1, XM_001684714.1
XP_001684768.1, XM_001684716.1
XP_001684770.1, XM_001684718.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi5664.LmjF.30.1660

Genome annotation databases

EnsemblProtistsiCAJ06282; CAJ06282; LMJF_30_1625
CAJ06285; CAJ06285; LMJF_30_1630
CAJ06287; CAJ06287; LMJF_30_1635
CAJ06289; CAJ06289; LMJF_30_1640
CAJ06291; CAJ06291; LMJF_30_1645
CAJ06293; CAJ06293; LMJF_30_1650
CAJ06295; CAJ06295; LMJF_30_1660
GeneDBiLmjF.30.1625:pep
LmjF.30.1630:pep
LmjF.30.1635:pep
LmjF.30.1640:pep
LmjF.30.1645:pep
LmjF.30.1650:pep
LmjF.30.1660:pep
GeneIDi5653697
5653699
5653701
5653703
5653705
5653707
5653709
KEGGilma:LMJF_30_1625
lma:LMJF_30_1630
lma:LMJF_30_1635
lma:LMJF_30_1640
lma:LMJF_30_1645
lma:LMJF_30_1650
lma:LMJF_30_1660

Organism-specific databases

EuPathDBiTriTrypDB:LmjF.30.1625
TriTrypDB:LmjF.30.1630
TriTrypDB:LmjF.30.1635
TriTrypDB:LmjF.30.1640
TriTrypDB:LmjF.30.1645
TriTrypDB:LmjF.30.1650
TriTrypDB:LmjF.30.1660

Phylogenomic databases

eggNOGiKOG3318 Eukaryota
ENOG41118KQ LUCA
HOGENOMiCLU_098404_3_0_1
KOiK23565

Family and domain databases

InterProiView protein in InterPro
IPR009445 TMEM85/Emc4
PANTHERiPTHR19315 PTHR19315, 1 hit
PfamiView protein in Pfam
PF06417 DUF1077, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4Q7D8_LEIMA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4Q7D8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: June 17, 2020
This is version 70 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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