UniProtKB - Q4Q5L3 (Q4Q5L3_LEIMA)
Protein
Submitted name:
Putative ubiquitin carrier protein 4
Gene
LMJF_32_0700
Organism
Leishmania major
Status
Functioni
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 89 | Glycyl thioester intermediatePROSITE-ProRule annotation | 1 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- ligase activity Source: UniProtKB-KW
- ubiquitin conjugating enzyme activity Source: GO_Central
GO - Biological processi
- protein polyubiquitination Source: GO_Central
- ubiquitin-dependent protein catabolic process Source: GO_Central
Keywordsi
Molecular function | LigaseImported, TransferaseARBA annotation |
Biological process | Ubl conjugation pathwayUniRule annotationARBA annotation |
Ligand | ATP-bindingUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | ORF Names:LMJF_32_0700Imported |
Organismi | Leishmania majorImported |
Taxonomic identifieri | 5664 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Proteomesi |
|
Organism-specific databases
VEuPathDBi | TriTrypDB:LmjF.32.0700 |
Structurei
3D structure databases
SMRi | Q4Q5L3 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q4Q5L3 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 29 – 141 | UBC coreInterPro annotationAdd BLAST | 113 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 150 – 234 | DisorderedSequence analysisAdd BLAST | 85 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 161 – 181 | PolyampholyteSequence analysisAdd BLAST | 21 | |
Compositional biasi | 217 – 234 | AcidicSequence analysisAdd BLAST | 18 |
Sequence similaritiesi
Belongs to the ubiquitin-conjugating enzyme family.UniRule annotation
Phylogenomic databases
eggNOGi | KOG0416, Eukaryota |
HOGENOMi | CLU_030988_7_2_1 |
InParanoidi | Q4Q5L3 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q4Q5L3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGAGNLRSN RRREMDYMRL CNSTRKVYPS DTVAEFWVEF KGPEGTPYED
60 70 80 90 100
GTWMLHVQLP SDYPFKSPSI GFCNRILHPN VDERSGSVCL DVINQTWTPM
110 120 130 140 150
YQLENIFDVF LPQLLRYPNP SDPLNVQAAH LLHADRVGFD ALLREHVSTH
160 170 180 190 200
ATPQKALESI PEAYRPHDNT HEEEPDEANA KDTASDGPVN AGHSKGLTDS
210 220 230
SVTPTEDHRV MHDDIAIDGD EDVEAEYEPE EIDL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR796428 Genomic DNA Translation: CAJ08567.1 |
RefSeqi | XP_001685385.1, XM_001685333.1 |
Genome annotation databases
EnsemblProtistsi | CAJ08567; CAJ08567; LMJF_32_0700 |
GeneDBi | LmjF.32.0700:pep |
GeneIDi | 5656181 |
KEGGi | lma:LMJF_32_0700 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | FR796428 Genomic DNA Translation: CAJ08567.1 |
RefSeqi | XP_001685385.1, XM_001685333.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1YF9 | X-ray | 2.00 | A/B/C | 1-167 | [»] | |
SMRi | Q4Q5L3 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 5664.LmjF.32.0700 |
Genome annotation databases
EnsemblProtistsi | CAJ08567; CAJ08567; LMJF_32_0700 |
GeneDBi | LmjF.32.0700:pep |
GeneIDi | 5656181 |
KEGGi | lma:LMJF_32_0700 |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmjF.32.0700 |
Phylogenomic databases
eggNOGi | KOG0416, Eukaryota |
HOGENOMi | CLU_030988_7_2_1 |
InParanoidi | Q4Q5L3 |
Miscellaneous databases
EvolutionaryTracei | Q4Q5L3 |
Family and domain databases
CDDi | cd00195, UBCc, 1 hit |
Gene3Di | 3.10.110.10, 1 hit |
InterProi | View protein in InterPro IPR000608, UBQ-conjugat_E2 IPR023313, UBQ-conjugating_AS IPR016135, UBQ-conjugating_enzyme/RWD |
Pfami | View protein in Pfam PF00179, UQ_con, 1 hit |
SUPFAMi | SSF54495, SSF54495, 1 hit |
PROSITEi | View protein in PROSITE PS00183, UBIQUITIN_CONJUGAT_1, 1 hit PS50127, UBIQUITIN_CONJUGAT_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q4Q5L3_LEIMA | |
Accessioni | Q4Q5L3Primary (citable) accession number: Q4Q5L3 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 19, 2005 |
Last sequence update: | July 19, 2005 | |
Last modified: | February 10, 2021 | |
This is version 114 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |