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Protein
Submitted name:

NACHT

Gene

Nlrp2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
NACHTImported
Submitted name:
NLR family, pyrin domain-containing 2Imported
Gene namesi
Name:Nlrp2Imported
Synonyms:Nalp2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:3041206 Nlrp2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000035177

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045077

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini180 – 387NACHTInterPro annotationAdd BLAST208

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

eggNOGiENOG410IM14 Eukaryota
ENOG410ZI5C LUCA
GeneTreeiENSGT00900000140813
HOGENOMiHOG000294064
HOVERGENiHBG103856
KOiK19409
OMAiSYWVEMA
OrthoDBiEOG091G01Q7

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR004020 DAPIN
IPR011029 DEATH-like_dom_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR007111 NACHT_NTPase
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF13516 LRR_6, 3 hits
PF05729 NACHT, 1 hit
PF02758 PYRIN, 1 hit
SMARTiView protein in SMART
SM01289 PYRIN, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS50837 NACHT, 1 hit

Sequencei

Sequence statusi: Complete.

Q4PLS0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHFDPLGFN LKDVLRKLDK TELNNFKRTL RSCSLPDTMK QINKLTMDLA
60 70 80 90 100
NGAQLAEILT DHCPSAWIKR VTVQILEEIN RVDLAELVVK QIEEAVLKVP
110 120 130 140 150
EEKVSSKPRE PSGTLTFPWN FVQGAKRPED KQKEEWKTRY TAKWKQNFWP
160 170 180 190 200
KCNKEIYVVT ESYKTLLALC NPKIETPFAH AIVLHGPPGS GKTTMAKQLM
210 220 230 240 250
LEWSESKQAQ IFSCAFYISC REVNNTKPCT FAHLLSMDNP SWRDCVIRDL
260 270 280 290 300
ILGKEFLFVV DGFDELTFPA GALIRDLCGD WNTVKPVEVL LGSLLKRKMA
310 320 330 340 350
PHATLLVTTR TQSLHQIFVM MDQPLLVETL GFLEQEKQEY FQKYFEDEEG
360 370 380 390 400
EEEDKGEGKA LRALKEVRCN ADLYQMASLP TACGIFCLCL ELRMKKGEDL
410 420 430 440 450
SLTCQTYTSM FLNFLCEVFS SETCEDHLNE EFQILFKKIC ILAANSLLEQ
460 470 480 490 500
VPILCEEDFL TLKLNLNNLH PMVCRHILFK DSSSTHCLSF ICLGIQQLLA
510 520 530 540 550
AIIFVQELGQ ESKGVSKYSI QNMLSREARL KNPDLSGLLP FVFGLLNETR
560 570 580 590 600
IQELKTTFGC QISTEVKRKF LECESGENKP LLLLMNMQEI LSCLYESQEE
610 620 630 640 650
GFVKEAMVLF EDISLHLKTS TDLIHASFCL KNSQNLQTMS LKVEKAVFPE
660 670 680 690 700
NVAALESTAK HQRSPDEQRM LTFWTDFCDT FNSNKKLVFL DIHESFLNSS
710 720 730 740 750
ALEILCEKLP SASCCLQKVV LKNISPDDAY EKLCLIFNGY KTISHLILQG
760 770 780 790 800
GNLDSMHHSL CEVLKNPACN LKFLSLGSCS TAAQKWDDFF PVLKVNQSLI
810 820 830 840 850
FLDLTDNSLL DKSAKLLCNI WKEPKCILQR VSLENCQLTE ACCKDLSSVL
860 870 880 890 900
MVSRTLTHLS LANNKLGDNG VKNLCESISC TECNLQTLVL WSCNITNAGC
910 920 930 940 950
HYLSKMLKQT LSLKHLDLGL NRIGTKGAKF LCEALKNPKS KLKSLWLCGC
960 970 980 990 1000
SITPLNCQDF SETLRSNKSL NTLDLSQNVL GTDAIKTFCE ALKLQICPLQ
1010 1020 1030 1040
MLRLKFDEAK PSIQNLIQEM KVSHPQLRIS SDQVDLKNPP LPHFIF
Length:1,046
Mass (Da):118,641
Last modified:July 19, 2005 - v1
Checksum:iC504DCA8693D02C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC155171 Genomic DNA No translation available.
DQ066881 mRNA Translation: AAY68479.1
RefSeqiNP_808358.2, NM_177690.3
UniGeneiMm.246598

Genome annotation databases

EnsembliENSMUST00000045022; ENSMUSP00000045077; ENSMUSG00000035177
GeneIDi232827
KEGGimmu:232827
UCSCiuc009fae.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ4PLS0_MOUSE
AccessioniPrimary (citable) accession number: Q4PLS0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 19, 2005
Last sequence update: July 19, 2005
Last modified: June 20, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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