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Protein

Uronate isomerase

Gene

uxaC

Organism
Staphylococcus haemolyticus (strain JCSC1435)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucuronate = D-fructuronate.UniRule annotation
D-galacturonate = D-tagaturonate.UniRule annotation

Pathwayi: pentose and glucuronate interconversion

This protein is involved in the pathway pentose and glucuronate interconversion, which is part of Carbohydrate metabolism.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway pentose and glucuronate interconversion and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase

Enzyme and pathway databases

BioCyciSHAE279808:G1G27-2610-MONOMER
UniPathwayi
UPA00246

Names & Taxonomyi

Protein namesi
Recommended name:
Uronate isomeraseUniRule annotation (EC:5.3.1.12UniRule annotation)
Alternative name(s):
Glucuronate isomeraseUniRule annotation
Uronic isomeraseUniRule annotation
Gene namesi
Name:uxaCUniRule annotation
Ordered Locus Names:SH2648
OrganismiStaphylococcus haemolyticus (strain JCSC1435)
Taxonomic identifieri279808 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcaceaeStaphylococcus
Proteomesi
  • UP000000543 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000447791 – 467Uronate isomeraseAdd BLAST467

Interactioni

Protein-protein interaction databases

STRINGi279808.SH2648

Structurei

3D structure databases

ProteinModelPortaliQ4L320
SMRiQ4L320
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D2H Bacteria
COG1904 LUCA
HOGENOMiHOG000224075
KOiK01812
OMAiFREMTTE
OrthoDBiPOG091H07GL

Family and domain databases

HAMAPiMF_00675 UxaC, 1 hit
InterProiView protein in InterPro
IPR032466 Metal_Hydrolase
IPR003766 Uronate_isomerase
PfamiView protein in Pfam
PF02614 UxaC, 1 hit
SUPFAMiSSF51556 SSF51556, 1 hit

Sequencei

Sequence statusi: Complete.

Q4L320-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAFINEHFML NNETGKHLYH DFAKDMPIYD YHCHLDPKQI SDNVACDNIT
60 70 80 90 100
DLWLSGDHYK WRAMRAQGIE EQYITGDAAP LDKFKKWTET LENSVGNPLY
110 120 130 140 150
HWSQLELKMY FDIEDLLTSD NAEAIYHRAN DYLKQHHTTT QSLITDSNVN
160 170 180 190 200
LICTTDNPTD DLNYHDAIKA KDGFNTTVLP AFRPDDVFKV GDPAFTDLLQ
210 220 230 240 250
KLENLTHPIT TPSDFIEALY KRIQYFHDKG GRLADHGLEE MHFEAYTDQA
260 270 280 290 300
IQDIFKKALN HADISTYERF QFQSYMLNEL SKAYYERGWV MQIHFGAIRN
310 320 330 340 350
NNTKMFEKVG KDAGFDSIRD QDNLAYHLNA TLDMMEQEGH LPKTILYNLN
360 370 380 390 400
PIYNDIVGST IANFQTEPGI KSKVQHGAGW WFNDTKRGML RQMSSLADQG
410 420 430 440 450
LLMHFVGMLT DSRSFISYSR HDYFRRILSS FIGDLVEKGE IPNDDQLLKR
460
MIENICYNNA YNYFKLI
Length:467
Mass (Da):54,328
Last modified:August 2, 2005 - v1
Checksum:iD3DE78446DD3CE1A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA Translation: BAE05957.1
RefSeqiWP_011276887.1, NC_007168.1

Genome annotation databases

EnsemblBacteriaiBAE05957; BAE05957; SH2648
GeneIDi24246857
KEGGisha:SH2648

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP006716 Genomic DNA Translation: BAE05957.1
RefSeqiWP_011276887.1, NC_007168.1

3D structure databases

ProteinModelPortaliQ4L320
SMRiQ4L320
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi279808.SH2648

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAE05957; BAE05957; SH2648
GeneIDi24246857
KEGGisha:SH2648

Phylogenomic databases

eggNOGiENOG4105D2H Bacteria
COG1904 LUCA
HOGENOMiHOG000224075
KOiK01812
OMAiFREMTTE
OrthoDBiPOG091H07GL

Enzyme and pathway databases

UniPathwayi
UPA00246

BioCyciSHAE279808:G1G27-2610-MONOMER

Family and domain databases

HAMAPiMF_00675 UxaC, 1 hit
InterProiView protein in InterPro
IPR032466 Metal_Hydrolase
IPR003766 Uronate_isomerase
PfamiView protein in Pfam
PF02614 UxaC, 1 hit
SUPFAMiSSF51556 SSF51556, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiUXAC_STAHJ
AccessioniPrimary (citable) accession number: Q4L320
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: August 2, 2005
Last modified: April 25, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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