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Protein
Submitted name:

Short stature homeobox isoform a

Gene

SHOX

Organism
Canis lupus familiaris (Dog) (Canis familiaris)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi116 – 175HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinPROSITE-ProRule annotation, DNA-bindingPROSITE-ProRule annotationSAAS annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Short stature homeobox isoform aImported
Gene namesi
Name:SHOXImported
OrganismiCanis lupus familiaris (Dog) (Canis familiaris)Imported
Taxonomic identifieri9615 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaCanidaeCanis

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliQ4KPC9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini114 – 174HomeoboxInterPro annotationAdd BLAST61
Domaini273 – 286OARInterPro annotationAdd BLAST14

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi273 – 286OARPROSITE-ProRule annotationAdd BLAST14

Sequence similaritiesi

Belongs to the paired homeobox family.SAAS annotation

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
HOGENOMiHOG000231518
HOVERGENiHBG007233

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR000047 HTH_motif
IPR003654 OAR_dom
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03826 OAR, 1 hit
PRINTSiPR00031 HTHREPRESSR
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit
PS50803 OAR, 1 hit

Sequencei

Sequence statusi: Complete.

Q4KPC9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEELTAFVSK SFDQKSKETG GGGGGGGKKD SITYREVLES GLARSRELGS
60 70 80 90 100
SESSLQDITE SSGHCPVHLF KDHVDSDKDK LKEFGTGRAA EGVYECKEKR
110 120 130 140 150
EDVKSEDEDG QTKLKQRRSR TNFTLEQLNE LERLFDETHY PDAFMREELS
160 170 180 190 200
QRLGLSEARV HVWFQNRRAK CRKQENQMHK GVILGTASHL DACRVAPYVN
210 220 230 240 250
MGALRMPFQQ VQAQLQLEGV AHAHPHLHPH LAAHAPYLMF PPPPFGLPIA
260 270 280 290
SLAESASAAA VVAAAAKSNS KNSSIADLRL KARKHAEALG L
Length:291
Mass (Da):32,125
Last modified:August 2, 2005 - v1
Checksum:i0BFD783D0F7F53AE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH014897
, AY954461, AY954462, AY954464 Genomic DNA Translation: AAY58046.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH014897
, AY954461, AY954462, AY954464 Genomic DNA Translation: AAY58046.1

3D structure databases

ProteinModelPortaliQ4KPC9
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
HOGENOMiHOG000231518
HOVERGENiHBG007233

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR000047 HTH_motif
IPR003654 OAR_dom
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF03826 OAR, 1 hit
PRINTSiPR00031 HTHREPRESSR
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit
PS50803 OAR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ4KPC9_CANLF
AccessioniPrimary (citable) accession number: Q4KPC9
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: October 10, 2018
This is version 109 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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