Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Cell adhesion molecule-related/down-regulated by oncogenes

Gene

CDON

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of a cell-surface receptor complex that mediates cell-cell interactions between muscle precursor cells. Promotes differentiation of myogenic cells (By similarity).By similarity

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-HSA-375170 CDO in myogenesis
R-HSA-5632681 Ligand-receptor interactions
R-HSA-5635838 Activation of SMO
SIGNORiQ4KMG0

Names & Taxonomyi

Protein namesi
Recommended name:
Cell adhesion molecule-related/down-regulated by oncogenes
Gene namesi
Name:CDON
Synonyms:CDO
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000064309.14
HGNCiHGNC:17104 CDON
MIMi608707 gene
neXtProtiNX_Q4KMG0

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini26 – 963ExtracellularSequence analysisAdd BLAST938
Transmembranei964 – 984HelicalSequence analysisAdd BLAST21
Topological domaini985 – 1287CytoplasmicSequence analysisAdd BLAST303

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Involvement in diseasei

Holoprosencephaly 11 (HPE11)1 Publication
The disease is caused by mutations affecting the gene represented in this entry.
Disease descriptionA structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.
See also OMIM:614226
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_066497684T → S in HPE11. 1 PublicationCorresponds to variant dbSNP:rs145983470EnsemblClinVar.1
Natural variantiVAR_066498689P → A in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906995EnsemblClinVar.1
Natural variantiVAR_066499691V → M in HPE11. 1 PublicationCorresponds to variant dbSNP:rs139323558Ensembl.1
Natural variantiVAR_066500780V → E in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906996EnsemblClinVar.1
Natural variantiVAR_066501790T → A in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906997EnsemblClinVar.1
Natural variantiVAR_066502940S → R in HPE11. 1 PublicationCorresponds to variant dbSNP:rs369673018EnsemblClinVar.1

Keywords - Diseasei

Disease mutation, Holoprosencephaly

Organism-specific databases

DisGeNETi50937
MalaCardsiCDON
MIMi614226 phenotype
OpenTargetsiENSG00000064309
Orphaneti93925 Alobar holoprosencephaly
93924 Lobar holoprosencephaly
280200 Microform holoprosencephaly
93926 Midline interhemispheric variant of holoprosencephaly
95496 Pituitary stalk interruption syndrome
220386 Semilobar holoprosencephaly
280195 Septopreoptic holoprosencephaly
PharmGKBiPA26328

Polymorphism and mutation databases

BioMutaiCDON
DMDMi308153422

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_000023405426 – 1287Cell adhesion molecule-related/down-regulated by oncogenesAdd BLAST1262

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi50 ↔ 97PROSITE-ProRule annotation
Glycosylationi88N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi100N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi141 ↔ 191PROSITE-ProRule annotation
Glycosylationi180N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi243 ↔ 290PROSITE-ProRule annotation
Glycosylationi287N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi294N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi333 ↔ 380PROSITE-ProRule annotation
Glycosylationi342N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi426 ↔ 500PROSITE-ProRule annotation
Glycosylationi427N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi570N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi873N-linked (GlcNAc...) asparagineSequence analysis1

Post-translational modificationi

N-glycosylated.By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

EPDiQ4KMG0
MaxQBiQ4KMG0
PaxDbiQ4KMG0
PeptideAtlasiQ4KMG0
PRIDEiQ4KMG0
ProteomicsDBi62193
62194 [Q4KMG0-2]

PTM databases

iPTMnetiQ4KMG0
PhosphoSitePlusiQ4KMG0

Expressioni

Gene expression databases

BgeeiENSG00000064309 Expressed in 161 organ(s), highest expression level in layer of synovial tissue
CleanExiHS_CDON
ExpressionAtlasiQ4KMG0 baseline and differential
GenevisibleiQ4KMG0 HS

Organism-specific databases

HPAiCAB012422
HPA017377

Interactioni

Subunit structurei

Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3 (By similarity). Interacts with PTCH1 (By similarity). Interacts with GAS1 (By similarity). Interacts with DHH, IHH and SHH.By similarity2 Publications

Binary interactionsi

Protein-protein interaction databases

BioGridi119165, 11 interactors
DIPiDIP-57226N
IntActiQ4KMG0, 5 interactors
MINTiQ4KMG0
STRINGi9606.ENSP00000263577

Structurei

Secondary structure

11287
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

ProteinModelPortaliQ4KMG0
SMRiQ4KMG0
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ4KMG0

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 114Ig-like C2-type 1Add BLAST86
Domaini120 – 204Ig-like C2-type 2Add BLAST85
Domaini225 – 303Ig-like C2-type 3Add BLAST79
Domaini310 – 396Ig-like C2-type 4Add BLAST87
Domaini405 – 516Ig-like C2-type 5Add BLAST112
Domaini579 – 677Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST99
Domaini723 – 821Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST99
Domaini826 – 926Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST101

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410IHIH Eukaryota
ENOG410XSVT LUCA
GeneTreeiENSGT00930000150975
HOGENOMiHOG000060072
HOVERGENiHBG081073
InParanoidiQ4KMG0
KOiK20033
OMAiMRTSDWL
OrthoDBiEOG091G00TB
PhylomeDBiQ4KMG0
TreeFamiTF332268

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 8 hits
InterProiView protein in InterPro
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PANTHERiPTHR44170:SF1 PTHR44170:SF1, 1 hit
PfamiView protein in Pfam
PF00041 fn3, 3 hits
PF07679 I-set, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SUPFAMiSSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 5 hits

Sequences (2+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q4KMG0-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MHPDLGPLCT LLYVTLTILC SSVSSDLAPY FTSEPLSAVQ KLGGPVVLHC
60 70 80 90 100
SAQPVTTRIS WLHNGKTLDG NLEHVKIHQG TLTILSLNSS LLGYYQCLAN
110 120 130 140 150
NSIGAIVSGP ATVSVAVLGD FGSSTKHVIT AEEKSAGFIG CRVPESNPKA
160 170 180 190 200
EVRYKIRGKW LEHSTENYLI LPSGNLQILN VSLEDKGSYK CAAYNPVTHQ
210 220 230 240 250
LKVEPIGRKL LVSRPSSDDV HILHPTHSQA LAVLSRSPVT LECVVSGVPA
260 270 280 290 300
PQVYWLKDGQ DIAPGSNWRR LYSHLATDSV DPADSGNYSC MAGNKSGDVK
310 320 330 340 350
YVTYMVNVLE HASISKGLQD QIVSLGATVH FTCDVHGNPA PNCTWFHNAQ
360 370 380 390 400
PIHPSARHLT AGNGLKISGV TVEDVGMYQC VADNGIGFMH STGRLEIEND
410 420 430 440 450
GGFKPVIITA PVSAKVADGD FVTLSCNASG LPVPVIRWYD SHGLITSHPS
460 470 480 490 500
QVLRSKSRKS QLSRPEGLNL EPVYFVLSQA GASSLHIQAV TQEHAGKYIC
510 520 530 540 550
EAANEHGTTQ AEASLMVVPF ETNTKAETVT LPDAAQNDDR SKRDGSETGL
560 570 580 590 600
LSSFPVKVHP SAVESAPEKN ASGISVPDAP IILSPPQTHT PDTYNLVWRA
610 620 630 640 650
GKDGGLPINA YFVKYRKLDD GVGMLGSWHT VRVPGSENEL HLAELEPSSL
660 670 680 690 700
YEVLMVARSA AGEGQPAMLT FRTSKEKTAS SKNTQASSPP VGIPKYPVVS
710 720 730 740 750
EAANNNFGVV LTDSSRHSGV PEAPDRPTIS TASETSVYVT WIPRANGGSP
760 770 780 790 800
ITAFKVEYKR MRTSNWLVAA EDIPPSKLSV EVRSLEPGST YKFRVIAINH
810 820 830 840 850
YGESFRSSAS RPYQVVGFPN RFSSRPITGP HIAYTEAVSD TQIMLKWTYI
860 870 880 890 900
PSSNNNTPIQ GFYIYYRPTD SDNDSDYKRD VVEGSKQWHM IGHLQPETSY
910 920 930 940 950
DIKMQCFNEG GESEFSNVMI CETKVKRVPG ASEYPVKDLS TPPNSLGSGG
960 970 980 990 1000
NVGPATSPAR SSDMLYLIVG CVLGVMVLIL MVFIAMCLWK NRQQNTIQKY
1010 1020 1030 1040 1050
DPPGYLYQGS DMNGQMVDYT TLSGASQING NVHGGFLTNG GLSSGYSHLH
1060 1070 1080 1090 1100
HKVPNAVNGI VNGSLNGGLY SGHSNSLTRT HVDFEHPHHL VNGGGMYTAV
1110 1120 1130 1140 1150
PQIDPLECVN CRNCRNNNRC FTKTNSTFSS SPPPVVPVVA PYPQDGLEMK
1160 1170 1180 1190 1200
PLSHVKVPVC LTSAVPDCGQ LPEESVKDNV EPVPTQRTCC QDIVNDVSSD
1210 1220 1230 1240 1250
GSEDPAEFSR GQEGMINLRI PDHLQLAKSC VWEGDSCAHS ETEINIVSWN
1260 1270 1280
ALILPPVPEG CAEKTMWSPP GIPLDSPTEV LQQPRET
Length:1,287
Mass (Da):139,147
Last modified:October 5, 2010 - v2
Checksum:iB7870C66F5224BBE
GO
Isoform 2 (identifier: Q4KMG0-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1212-1234: Missing.

Show »
Length:1,264
Mass (Da):136,527
Checksum:i79AB36E0B52C61D7
GO

Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E9PNF2E9PNF2_HUMAN
Cell adhesion molecule-related/down...
CDON
111Annotation score:
E9PRD8E9PRD8_HUMAN
Cell adhesion molecule-related/down...
CDON
165Annotation score:
E9PPQ7E9PPQ7_HUMAN
Cell adhesion molecule-related/down...
CDON
142Annotation score:
E9PN78E9PN78_HUMAN
Cell adhesion molecule-related/down...
CDON
641Annotation score:
H0YEX4H0YEX4_HUMAN
Cell adhesion molecule-related/down...
CDON
650Annotation score:
H0YCZ4H0YCZ4_HUMAN
Cell adhesion molecule-related/down...
CDON
243Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti75V → I in AAC34901 (PubMed:9214393).Curated1
Sequence conflicti75V → I in AAH98583 (PubMed:15489334).Curated1
Sequence conflicti265G → E in AAH98583 (PubMed:15489334).Curated1
Sequence conflicti300K → E in AAC34901 (PubMed:9214393).Curated1
Sequence conflicti669L → I in AAC34901 (PubMed:9214393).Curated1
Sequence conflicti1244I → N in AAH98583 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05603866K → R. Corresponds to variant dbSNP:rs7122277EnsemblClinVar.1
Natural variantiVAR_056039162E → K. Corresponds to variant dbSNP:rs3740909EnsemblClinVar.1
Natural variantiVAR_056040351P → A. Corresponds to variant dbSNP:rs35665264EnsemblClinVar.1
Natural variantiVAR_066497684T → S in HPE11. 1 PublicationCorresponds to variant dbSNP:rs145983470EnsemblClinVar.1
Natural variantiVAR_056041686A → V. Corresponds to variant dbSNP:rs12274923EnsemblClinVar.1
Natural variantiVAR_066498689P → A in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906995EnsemblClinVar.1
Natural variantiVAR_066499691V → M in HPE11. 1 PublicationCorresponds to variant dbSNP:rs139323558Ensembl.1
Natural variantiVAR_066500780V → E in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906996EnsemblClinVar.1
Natural variantiVAR_066501790T → A in HPE11. 1 PublicationCorresponds to variant dbSNP:rs387906997EnsemblClinVar.1
Natural variantiVAR_066502940S → R in HPE11. 1 PublicationCorresponds to variant dbSNP:rs369673018EnsemblClinVar.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0182011212 – 1234Missing in isoform 2. 1 PublicationAdd BLAST23

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004841 mRNA Translation: AAC34901.2
AP000821 Genomic DNA No translation available.
AP000842 Genomic DNA No translation available.
BC098583 mRNA Translation: AAH98583.1
CCDSiCCDS58192.1 [Q4KMG0-1]
CCDS8468.1 [Q4KMG0-2]
PIRiT03097
RefSeqiNP_001230526.1, NM_001243597.1 [Q4KMG0-1]
NP_058648.4, NM_016952.4 [Q4KMG0-2]
XP_011541164.1, XM_011542862.2 [Q4KMG0-1]
XP_011541165.1, XM_011542863.2 [Q4KMG0-1]
XP_011541166.1, XM_011542864.2 [Q4KMG0-1]
XP_011541167.1, XM_011542865.2 [Q4KMG0-1]
XP_011541168.1, XM_011542866.2 [Q4KMG0-2]
XP_016873362.1, XM_017017873.1 [Q4KMG0-1]
UniGeneiHs.38034

Genome annotation databases

EnsembliENST00000263577; ENSP00000263577; ENSG00000064309 [Q4KMG0-2]
ENST00000392693; ENSP00000376458; ENSG00000064309 [Q4KMG0-1]
GeneIDi50937
KEGGihsa:50937
UCSCiuc001qdc.5 human [Q4KMG0-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004841 mRNA Translation: AAC34901.2
AP000821 Genomic DNA No translation available.
AP000842 Genomic DNA No translation available.
BC098583 mRNA Translation: AAH98583.1
CCDSiCCDS58192.1 [Q4KMG0-1]
CCDS8468.1 [Q4KMG0-2]
PIRiT03097
RefSeqiNP_001230526.1, NM_001243597.1 [Q4KMG0-1]
NP_058648.4, NM_016952.4 [Q4KMG0-2]
XP_011541164.1, XM_011542862.2 [Q4KMG0-1]
XP_011541165.1, XM_011542863.2 [Q4KMG0-1]
XP_011541166.1, XM_011542864.2 [Q4KMG0-1]
XP_011541167.1, XM_011542865.2 [Q4KMG0-1]
XP_011541168.1, XM_011542866.2 [Q4KMG0-2]
XP_016873362.1, XM_017017873.1 [Q4KMG0-1]
UniGeneiHs.38034

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3D1MX-ray1.70C/D826-924[»]
3N1FX-ray1.60C/D826-924[»]
3N1QX-ray2.89C/D/F826-924[»]
ProteinModelPortaliQ4KMG0
SMRiQ4KMG0
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi119165, 11 interactors
DIPiDIP-57226N
IntActiQ4KMG0, 5 interactors
MINTiQ4KMG0
STRINGi9606.ENSP00000263577

PTM databases

iPTMnetiQ4KMG0
PhosphoSitePlusiQ4KMG0

Polymorphism and mutation databases

BioMutaiCDON
DMDMi308153422

Proteomic databases

EPDiQ4KMG0
MaxQBiQ4KMG0
PaxDbiQ4KMG0
PeptideAtlasiQ4KMG0
PRIDEiQ4KMG0
ProteomicsDBi62193
62194 [Q4KMG0-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000263577; ENSP00000263577; ENSG00000064309 [Q4KMG0-2]
ENST00000392693; ENSP00000376458; ENSG00000064309 [Q4KMG0-1]
GeneIDi50937
KEGGihsa:50937
UCSCiuc001qdc.5 human [Q4KMG0-1]

Organism-specific databases

CTDi50937
DisGeNETi50937
EuPathDBiHostDB:ENSG00000064309.14
GeneCardsiCDON
H-InvDBiHIX0035847
HGNCiHGNC:17104 CDON
HPAiCAB012422
HPA017377
MalaCardsiCDON
MIMi608707 gene
614226 phenotype
neXtProtiNX_Q4KMG0
OpenTargetsiENSG00000064309
Orphaneti93925 Alobar holoprosencephaly
93924 Lobar holoprosencephaly
280200 Microform holoprosencephaly
93926 Midline interhemispheric variant of holoprosencephaly
95496 Pituitary stalk interruption syndrome
220386 Semilobar holoprosencephaly
280195 Septopreoptic holoprosencephaly
PharmGKBiPA26328
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IHIH Eukaryota
ENOG410XSVT LUCA
GeneTreeiENSGT00930000150975
HOGENOMiHOG000060072
HOVERGENiHBG081073
InParanoidiQ4KMG0
KOiK20033
OMAiMRTSDWL
OrthoDBiEOG091G00TB
PhylomeDBiQ4KMG0
TreeFamiTF332268

Enzyme and pathway databases

ReactomeiR-HSA-375170 CDO in myogenesis
R-HSA-5632681 Ligand-receptor interactions
R-HSA-5635838 Activation of SMO
SIGNORiQ4KMG0

Miscellaneous databases

ChiTaRSiCDON human
EvolutionaryTraceiQ4KMG0
GeneWikiiCDON
GenomeRNAii50937
PROiPR:Q4KMG0
SOURCEiSearch...

Gene expression databases

BgeeiENSG00000064309 Expressed in 161 organ(s), highest expression level in layer of synovial tissue
CleanExiHS_CDON
ExpressionAtlasiQ4KMG0 baseline and differential
GenevisibleiQ4KMG0 HS

Family and domain databases

CDDicd00063 FN3, 3 hits
Gene3Di2.60.40.10, 8 hits
InterProiView protein in InterPro
IPR032983 CDO
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR003599 Ig_sub
IPR003598 Ig_sub2
PANTHERiPTHR44170:SF1 PTHR44170:SF1, 1 hit
PfamiView protein in Pfam
PF00041 fn3, 3 hits
PF07679 I-set, 1 hit
SMARTiView protein in SMART
SM00060 FN3, 3 hits
SM00409 IG, 5 hits
SM00408 IGc2, 5 hits
SUPFAMiSSF48726 SSF48726, 5 hits
SSF49265 SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853 FN3, 3 hits
PS50835 IG_LIKE, 5 hits
ProtoNetiSearch...

Entry informationi

Entry nameiCDON_HUMAN
AccessioniPrimary (citable) accession number: Q4KMG0
Secondary accession number(s): O14631
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 2, 2006
Last sequence update: October 5, 2010
Last modified: November 7, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again