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Protein
Submitted name:

Irak3 protein

Gene

irak3

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • ATP binding Source: InterPro
  • protein serine/threonine kinase activity Source: GO_Central

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Irak3 proteinImported
Gene namesi
Name:irak3Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-060503-710 irak3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini60 – 128DeathInterPro annotationAdd BLAST69
Domaini184 – 469Protein kinaseInterPro annotationAdd BLAST286

Phylogenomic databases

eggNOGiKOG1187 Eukaryota
COG0515 LUCA
HOVERGENiHBG052146
PhylomeDBiQ4KMD6

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR033610 IRAK3
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
PANTHERiPTHR24419:SF7 PTHR24419:SF7, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Fragment.

Q4KMD6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
VESSSSSVSE RGMKHPNIIT FTPGSTRNMS GNTEPSTLLF DVPPVLMESF
60 70 80 90 100
CRLMDSGVDG LGWRTLASRI LSSQLEVRCI EMYAVAGKSP TKELMWSWAQ
110 120 130 140 150
RNKTVEDLLK VLDEMGHARA RSLFQSQDSC VLKSSSPPHY PTYLRSTGKS
160 170 180 190 200
CQVSDLHAES VSVEGEKQKC FITYFDVIEG TRHFHQDLKI GGSGFAEVYC
210 220 230 240 250
GRWGNRSFAV KVFKQENKTD WKALWEKFTK EIEVLQLNQH PNILELWGSF
260 270 280 290 300
SDSDRFCLVY PFLQNGSLFH RLHKHVDKPL SWQERLNIIK GTAKAVHHLH
310 320 330 340 350
TSQPCTVICG NITSSNILLD ENMQPKLCDF GLARLRPHSV DQSCTIVMNT
360 370 380 390 400
ALHSNLGYLP EEYIRDGKLS VKLDVYSLGV VILETCTGQK VKQESSKNLF
410 420 430 440 450
LRGVLHSEVE EKGCVDACLR FLDLKFEHWP PAVALCLLRL GLECTGSKMR
460 470 480 490 500
VRPDMEMVLQ RLIPLHPLPA FSEDQPHTLD DTIPPQRPYK SFPIEDDEMH
510 520 530 540 550
SQLEELHSPR VSKPADPCEC SQSEVTFLSN EDRSFLRDCH QESDQRVSSS
560 570 580 590 600
ESVHSDSAAR LDLYGSWPVE CSCSTETEAQ ACADCCANGF SQSVVYVTID
610 620
DDNALPAPND ARNPAKEKKK K
Length:621
Mass (Da):69,893
Last modified:August 2, 2005 - v1
Checksum:iEB04962E1DBDFD82
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei621Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098615 mRNA Translation: AAH98615.1
UniGeneiDr.90054

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098615 mRNA Translation: AAH98615.1
UniGeneiDr.90054

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-060503-710 irak3

Phylogenomic databases

eggNOGiKOG1187 Eukaryota
COG0515 LUCA
HOVERGENiHBG052146
PhylomeDBiQ4KMD6

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR033610 IRAK3
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
PANTHERiPTHR24419:SF7 PTHR24419:SF7, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ4KMD6_DANRE
AccessioniPrimary (citable) accession number: Q4KMD6
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: November 7, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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