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Protein

tRNA pseudouridine synthase A

Gene

truA

Organism
Corynebacterium jeikeium (strain K411)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.UniRule annotationSAAS annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Catalytic activityi

tRNA uridine(38-40) = tRNA pseudouridine(38-40).UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei80NucleophileUniRule annotation1
Binding sitei145SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotation, LyaseImported
Biological processtRNA processingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase AUniRule annotation (EC:5.4.99.12UniRule annotation)
Alternative name(s):
tRNA pseudouridine(38-40) synthaseUniRule annotation
tRNA pseudouridylate synthase IUniRule annotation
tRNA-uridine isomerase IUniRule annotation
Gene namesi
Name:truAUniRule annotationImported
Ordered Locus Names:jk1755Imported
OrganismiCorynebacterium jeikeium (strain K411)Imported
Taxonomic identifieri306537 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesCorynebacteriaceaeCorynebacterium
Proteomesi
  • UP000000545 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

STRINGi306537.jk1755

Structurei

3D structure databases

ProteinModelPortaliQ4JTC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 138PseudoU_synth_1InterPro annotationAdd BLAST103
Domaini179 – 285PseudoU_synth_1InterPro annotationAdd BLAST107

Sequence similaritiesi

Belongs to the tRNA pseudouridine synthase TruA family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DI7 Bacteria
COG0101 LUCA
HOGENOMiHOG000248674
KOiK06173
OMAiFLYGMVR
OrthoDBiPOG091H010Q

Family and domain databases

Gene3Di3.30.70.660, 1 hit
HAMAPiMF_00171 TruA, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR001406 PsdUridine_synth_TruA
IPR020097 PsdUridine_synth_TruA_a/b_dom
IPR020095 PsdUridine_synth_TruA_C
PANTHERiPTHR11142 PTHR11142, 1 hit
PfamiView protein in Pfam
PF01416 PseudoU_synth_1, 2 hits
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00071 hisT_truA, 1 hit

Sequencei

Sequence statusi: Complete.

Q4JTC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPETPQAQQF SQATSAAPAD QPSQAGELVR VRLEVAYDGT DFHGWATQSG
60 70 80 90 100
GLRTVAGVLQ EKLSLVTRHP IELVVAGRTD AGVHASGQVC HADIPVDAFE
110 120 130 140 150
QRSLTRPEDL VRRLSRMLPA DVRLHGASVA PQGFDARFSA LRRHYIYRVT
160 170 180 190 200
THPAGPVPVR ARDTAAWRHP IDLEKTQAAS DALIGLNDFA AFCKAREGAT
210 220 230 240 250
TVRELQEFRW VDVSTEAEPQ TYEAHVTADA FCWSMVRSLV GAALTVGSGK
260 270 280 290 300
RPDDFTPGLL KETKRSSAVP VAPAEGLNLV RVDYPADEEL AERALTTRAK
310 320
RSPVGSGSGS AEAAAVDAGP AAGPDTAP
Length:328
Mass (Da):35,030
Last modified:August 2, 2005 - v1
Checksum:i1647E4A925EC18FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR931997 Genomic DNA Translation: CAI37932.1
RefSeqiWP_011274112.1, NC_007164.1

Genome annotation databases

EnsemblBacteriaiCAI37932; CAI37932; jk1755
GeneIDi3433058
KEGGicjk:jk1755
PATRICifig|306537.10.peg.1778

Similar proteinsi

Entry informationi

Entry nameiQ4JTC5_CORJK
AccessioniPrimary (citable) accession number: Q4JTC5
Entry historyiIntegrated into UniProtKB/TrEMBL: August 2, 2005
Last sequence update: August 2, 2005
Last modified: July 18, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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