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Protein
Submitted name:

DMD protein

Gene

DMD

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionActin-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
DMD proteinImported
Submitted name:
DystrophinImported
Gene namesi
Name:DMDImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

EuPathDBiHostDB:ENSG00000198947.15
HGNCiHGNC:2928 DMD

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198947
PharmGKBiPA27378

PTM / Processingi

Proteomic databases

MaxQBiQ4G0X0
PRIDEiQ4G0X0

Expressioni

Gene expression databases

BgeeiENSG00000198947

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ4G0X0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 111Calponin-homology (CH)InterPro annotationAdd BLAST105
Domaini126 – 232Calponin-homology (CH)InterPro annotationAdd BLAST107

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili449 – 469Sequence analysisAdd BLAST21
Coiled coili475 – 498Sequence analysisAdd BLAST24

Keywords - Domaini

Coiled coilSequence analysis, RepeatSAAS annotation

Phylogenomic databases

eggNOGiKOG4286 Eukaryota
COG5069 LUCA
GeneTreeiENSGT00760000119237
HOGENOMiHOG000134526
HOVERGENiHBG097030

Family and domain databases

CDDicd00014 CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589 Actinin_actin-bd_CS
IPR001715 CH-domain
IPR036872 CH_dom_sf
IPR016344 Dystrophin
IPR018159 Spectrin/alpha-actinin
IPR002017 Spectrin_repeat
PANTHERiPTHR44318:SF1 PTHR44318:SF1, 1 hit
PfamiView protein in Pfam
PF00307 CH, 2 hits
PF00435 Spectrin, 2 hits
SMARTiView protein in SMART
SM00033 CH, 2 hits
SM00150 SPEC, 3 hits
SUPFAMiSSF47576 SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019 ACTININ_1, 1 hit
PS00020 ACTININ_2, 1 hit
PS50021 CH, 2 hits

Sequencei

Sequence statusi: Complete.

Q4G0X0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEDEREDVQK KTFTKWVNAQ FSKFGKQHIE NLFSDLQDGR RLLDLLEGLT
60 70 80 90 100
GQKLPKEKGS TRVHALNNVN KALRVLQNNN VDLVNIGSTD IVDGNHKLTL
110 120 130 140 150
GLIWNIILHW QVKNVMKNIM AGLQQTNSEK ILLSWVRQST RNYPQVNVIN
160 170 180 190 200
FTTSWSDGLA LNALIHSHRP DLFDWNSVVC QQSATQRLEH AFNIARYQLG
210 220 230 240 250
IEKLLDPEDV DTTYPDKKSI LMYITSLFQV LPQQVSIEAI QEVEMLPRPP
260 270 280 290 300
KVTKEEHFQL HHQMHYSQQI TVSLAQGYER TSSPKPRFKS YAYTQAAYVT
310 320 330 340 350
TSDPTRSPFP SQHLEAPEDK SFGSSLMESE VNLDRYQTAL EEVLSWLLSA
360 370 380 390 400
EDTLQAQGEI SNDVEVVKDQ FHTHEGYMMD LTAHQGRVGN ILQLGSKLIG
410 420 430 440 450
TGKLSEDEET EVQEQMNLLN SRWECLRVAS MEKQSNLHRV LMDLQNQKLK
460 470 480 490 500
ELNDWLTKTE ERTRKMEEEP LGPDLEDLKR QVQQHKVLQE DLEQEQVRVN
510 520 530 540 550
SLTHMVVVVD ESSGDHATAA LEEQLKVLGD RWANICRWTE DRWVLLQDIL
560 570 580 590 600
LKWQRLTEEQ CLFSAWLSEK EDAVNKIHTT GFKDQNEMLS SLQKLAVLKA
610 620 630 640 650
DLEKKKQSMG KLYSLKQDLL STLKNKSVTQ KTEAWLDNFA RCWDNLVQKL
660 670 680 690 700
EKSTAQISQA VTTTQPSLTQ TTVMETVTTV TTREQILVKH AQEELPPPPP
710 720 730 740 750
QKKRQITVDS EIRKRLDVDI TELHSWITRS EAVLQSPEFA IFRKEGNFSD
760 770
LKEKVNVGYA LIFISVLILC CL
Length:772
Mass (Da):88,800
Last modified:February 5, 2008 - v1
Checksum:i33AEE50114531EBA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC006061 Genomic DNA No translation available.
AC078957 Genomic DNA No translation available.
AC078958 Genomic DNA No translation available.
AC079143 Genomic DNA No translation available.
AC079175 Genomic DNA No translation available.
AC079177 Genomic DNA No translation available.
AC079864 Genomic DNA No translation available.
AC090632 Genomic DNA No translation available.
AC093167 Genomic DNA No translation available.
AC093193 Genomic DNA No translation available.
BC036103 mRNA Translation: AAH36103.1
RefSeqiNP_000100.2, NM_000109.3
UniGeneiHs.495912

Genome annotation databases

EnsembliENST00000288447; ENSP00000288447; ENSG00000198947
GeneIDi1756
UCSCiuc004ddf.4 human

Similar proteinsi

Entry informationi

Entry nameiQ4G0X0_HUMAN
AccessioniPrimary (citable) accession number: Q4G0X0
Entry historyiIntegrated into UniProtKB/TrEMBL: February 5, 2008
Last sequence update: February 5, 2008
Last modified: July 18, 2018
This is version 90 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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