Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 90 (26 Feb. 2020)
Sequence version 2 (05 Oct. 2010)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Scavenger receptor cysteine-rich domain-containing protein SCART1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in the immune system, perhaps as a co-receptor on alphabeta and gammadelta T-cells.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processImmunity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scavenger receptor cysteine-rich domain-containing protein SCART1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q4G0T1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini20 – 906ExtracellularSequence analysisAdd BLAST887
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei907 – 927HelicalSequence analysisAdd BLAST21
Topological domaini928 – 1027CytoplasmicSequence analysisAdd BLAST100

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000214279

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q4G0T1 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
-

Domain mapping of disease mutations (DMDM)

More...
DMDMi
308153504

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000039939220 – 1027Scavenger receptor cysteine-rich domain-containing protein SCART1Add BLAST1008

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi53 ↔ 117PROSITE-ProRule annotation
Disulfide bondi66 ↔ 127PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi94N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi97 ↔ 107PROSITE-ProRule annotation
Glycosylationi129N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi160 ↔ 216PROSITE-ProRule annotation
Disulfide bondi171 ↔ 226PROSITE-ProRule annotation
Disulfide bondi196 ↔ 206PROSITE-ProRule annotation
Disulfide bondi253 ↔ 315PROSITE-ProRule annotation
Disulfide bondi266 ↔ 325PROSITE-ProRule annotation
Disulfide bondi297 ↔ 307PROSITE-ProRule annotation
Glycosylationi332N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi353 ↔ 417PROSITE-ProRule annotation
Disulfide bondi366 ↔ 427PROSITE-ProRule annotation
Disulfide bondi397 ↔ 407PROSITE-ProRule annotation
Disulfide bondi472 ↔ 533PROSITE-ProRule annotation
Disulfide bondi503 ↔ 513PROSITE-ProRule annotation
Disulfide bondi594 ↔ 655PROSITE-ProRule annotation
Disulfide bondi625 ↔ 635PROSITE-ProRule annotation
Disulfide bondi824 ↔ 885PROSITE-ProRule annotation
Disulfide bondi855 ↔ 865PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q4G0T1

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q4G0T1

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q4G0T1

PeptideAtlas

More...
PeptideAtlasi
Q4G0T1

PRoteomics IDEntifications database

More...
PRIDEi
Q4G0T1

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62127 [Q4G0T1-1]
62128 [Q4G0T1-2]

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Mainly expressed by CD4+ and CD8+ T lymphocytes. Also highly expressed in small intestine and colon. Expressed (at protein level) in small intestine, stomach, gall bladder, and placental villi.1 Publication

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA043101

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q4G0T1 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q4G0T1

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini28 – 128SRCR 1PROSITE-ProRule annotationAdd BLAST101
Domaini135 – 227SRCR 2PROSITE-ProRule annotationAdd BLAST93
Domaini232 – 326SRCR 3PROSITE-ProRule annotationAdd BLAST95
Domaini328 – 428SRCR 4PROSITE-ProRule annotationAdd BLAST101
Domaini434 – 534SRCR 5PROSITE-ProRule annotationAdd BLAST101
Domaini555 – 656SRCR 6PROSITE-ProRule annotationAdd BLAST102
Domaini661 – 761SRCR 7PROSITE-ProRule annotationAdd BLAST101
Domaini786 – 886SRCR 8PROSITE-ProRule annotationAdd BLAST101

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IHBC Eukaryota
ENOG410XQVR LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000162139

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q4G0T1

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.250.10, 8 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00530 SRCR, 8 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00258 SPERACTRCPTR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00202 SR, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56487 SSF56487, 8 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00420 SRCR_1, 1 hit
PS50287 SRCR_2, 8 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q4G0T1-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MRAALWTLGL GPLLLNLWAV PIGGPGALRL AYRHSTCDGV VLVRHHGAWG
60 70 80 90 100
YVCNQEWTLA EASVVCRQLG CGPAVGAPKY VPLPGEMAQP WLHNVSCRGN
110 120 130 140 150
ESSLWECSLG SWCQSPCPHA WVVVALCSNG TFRELRLVKG RSPCAGLPEI
160 170 180 190 200
RNVNGVDRLC VLHVEEAMVF CRELGCGPVL QAPRRDVGVV RKYLACRGTE
210 220 230 240 250
PTIRSCRLDN NFRSGCDLRL DAEVVCSGHT EARLVGGEHP CAGRLEVTWG
260 270 280 290 300
TVCDAALDLA TAHVVCRELQ CGAVVSTPEG ARFGRGSGPV WTEAFRCAGN
310 320 330 340 350
ESLLFHCPRG RGSQCGHGHD AGLRCSEFRM VNGSSSCEGR VEFQVQGSWA
360 370 380 390 400
PLCATHWDIA DATVLCHQLN CGNAVAAPGG GHFGDGDAAI WPDAFHCEGT
410 420 430 440 450
ESYLWNCPVS TLGAPACAPG NTASAVCSGL AHALRLREGQ SRCDGRVEVS
460 470 480 490 500
LDGVWGRVLD DAWDLRGAGV VCRQLGCRGA QQAYDAPAPS RGSVQVALSR
510 520 530 540 550
VRCLGTETRL TQCNVSATLQ EPAGTSRDAG VVCSGEVGTA SPMARRHGIP
560 570 580 590 600
GALTLSLHRE PQGAAGRGAG ALHGGAWGTV CDDAWDLRDA HVVCRQLGCG
610 620 630 640 650
RALSALGAAH FGAGAGRIWL DELGCQGHES ALWQCPSAGW GRHDWRHKED
660 670 680 690 700
AGVFCSESVA LRLRGGTCCC AGWLDVFYNG TWGAMCSNAL KDLSLSIICK
710 720 730 740 750
QLGCGVWGVG LAGEQALPLC GHRDRLGGQH RVPQAAQLHS VAMPFPPMAP
760 770 780 790 800
ALLRPSRAGL SEDRPQAAGE PLNCSSWLGC PEEGALRVRG GEDRCSGRVE
810 820 830 840 850
LWHAGSWGTV CDDGWDLADA EVVCRQLGCG RAVAALGAAA FGPGSGPVWL
860 870 880 890 900
DEVGCRGSEA SLWGCPAERW GRGDRAHEED AGVRCWEPGP GPPLPAAPFR
910 920 930 940 950
TFWVVSVVLG SLLGLLLLGL MAFLILPRVT QAMQRGLGRS EVSPGEAIYD
960 970 980 990 1000
VIGEMPPAGL YEEIMEAEAV LQDEEDGSVV KVDTEAAVSG EVSNLLEGQS
1010 1020
IRAEGGHSRP VSQGYDEAAF PLEEMTL
Length:1,027
Mass (Da):108,611
Last modified:October 5, 2010 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6E956AC67ECDA48D
GO
Isoform Gamma (identifier: Q4G0T1-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     229-232: HTEA → EAAT
     233-1027: Missing.

Show »
Length:232
Mass (Da):25,190
Checksum:i64AD58CC652C3A88
GO
Isoform Alpha (identifier: Q4G0T1-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     226-324: Missing.
     657-935: Missing.

Show »
Length:649
Mass (Da):68,842
Checksum:i91DB49F1C4E9017A
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti89Q → K in BC038300 (PubMed:15489334).Curated1
Sequence conflicti136R → G in BC038300 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_053841226 – 324Missing in isoform Alpha. 1 PublicationAdd BLAST99
Alternative sequenceiVSP_039839229 – 232HTEA → EAAT in isoform Gamma. 1 Publication4
Alternative sequenceiVSP_039840233 – 1027Missing in isoform Gamma. 1 PublicationAdd BLAST795
Alternative sequenceiVSP_053842657 – 935Missing in isoform Alpha. 1 PublicationAdd BLAST279

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AL161645 Genomic DNA No translation available.
BC038300 mRNA No translation available.

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL161645 Genomic DNA No translation available.
BC038300 mRNA No translation available.

3D structure databases

SMRiQ4G0T1
ModBaseiSearch...

Polymorphism and mutation databases

BioMutai-
DMDMi308153504

Proteomic databases

jPOSTiQ4G0T1
MassIVEiQ4G0T1
PaxDbiQ4G0T1
PeptideAtlasiQ4G0T1
PRIDEiQ4G0T1
ProteomicsDBi62127 [Q4G0T1-1]
62128 [Q4G0T1-2]

Organism-specific databases

GeneCards: human genes, protein and diseases

More...
GeneCardsi
SCART1
HPAiHPA043101
neXtProtiNX_Q4G0T1
OpenTargetsiENSG00000214279

Phylogenomic databases

eggNOGiENOG410IHBC Eukaryota
ENOG410XQVR LUCA
GeneTreeiENSGT00940000162139
PhylomeDBiQ4G0T1

Miscellaneous databases

PharosiQ4G0T1 Tdark
RNActiQ4G0T1 protein

Family and domain databases

Gene3Di3.10.250.10, 8 hits
InterProiView protein in InterPro
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
PfamiView protein in Pfam
PF00530 SRCR, 8 hits
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00202 SR, 7 hits
SUPFAMiSSF56487 SSF56487, 8 hits
PROSITEiView protein in PROSITE
PS00420 SRCR_1, 1 hit
PS50287 SRCR_2, 8 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSRCRM_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4G0T1
Secondary accession number(s): C9K0L3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: October 5, 2010
Last modified: February 26, 2020
This is version 90 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again