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Entry version 127 (07 Apr 2021)
Sequence version 1 (30 Aug 2005)
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Protein

Eukaryotic translation initiation factor 3 subunit B

Gene

Eif3b

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionInitiation factor, RNA-binding
Biological processProtein biosynthesis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-RNO-72649, Translation initiation complex formation
R-RNO-72689, Formation of a pool of free 40S subunits
R-RNO-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-RNO-72702, Ribosomal scanning and start codon recognition
R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Eukaryotic translation initiation factor 3 subunit BUniRule annotation
Short name:
eIF3bUniRule annotation
Alternative name(s):
Eukaryotic translation initiation factor 3 subunit 9UniRule annotation
eIF-3-etaUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Eif3b
Synonyms:Eif3s9
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Rat genome database

More...
RGDi
1309018, Eif3b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002234801 – 797Eukaryotic translation initiation factor 3 subunit BAdd BLAST797

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineUniRule annotationBy similarity1
Modified residuei31PhosphothreonineBy similarity1
Modified residuei37PhosphoserineCombined sources1
Modified residuei40PhosphoserineCombined sources1
Modified residuei68PhosphoserineUniRule annotationBy similarity1
Modified residuei72PhosphothreonineBy similarity1
Modified residuei75PhosphoserineCombined sources1
Modified residuei79PhosphoserineCombined sources1
Modified residuei84PhosphoserineBy similarity1
Modified residuei105PhosphoserineBy similarity1
Modified residuei114PhosphoserineCombined sources1
Modified residuei117PhosphoserineCombined sources1
Modified residuei135PhosphoserineCombined sources1
Modified residuei137PhosphoserineCombined sources1
Modified residuei147PhosphoserineCombined sources1
Modified residuei192N6-acetyllysineBy similarity1
Modified residuei222PhosphoserineUniRule annotationBy similarity1
Modified residuei271N6-acetyllysineBy similarity1
Modified residuei347N6-acetyllysineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated. Phosphorylation is enhanced upon serum stimulation.UniRule annotation

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q4G061

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q4G061

PRoteomics IDEntifications database

More...
PRIDEi
Q4G061

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q4G061

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q4G061

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000001253, Expressed in testis and 21 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q4G061, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is composed of 13 subunits: EIF3A, EIF3B, EIF3C, EIF3D, EIF3E, EIF3F, EIF3G, EIF3H, EIF3I, EIF3J, EIF3K, EIF3L and EIF3M. The eIF-3 complex appears to include 3 stable modules: module A is composed of EIF3A, EIF3B, EIF3G and EIF3I; module B is composed of EIF3F, EIF3H, and EIF3M; and module C is composed of EIF3C, EIF3D, EIF3E, EIF3K and EIF3L. EIF3C of module C binds EIF3B of module A and EIF3H of module B, thereby linking the three modules. EIF3J is a labile subunit that binds to the eIF-3 complex via EIF3B. The eIF-3 complex interacts with RPS6KB1 under conditions of nutrient depletion. Mitogenic stimulation leads to binding and activation of a complex composed of MTOR and RPTOR, leading to phosphorylation and release of RPS6KB1 and binding of EIF4B to eIF-3.

Also interacts with UPF2 and HNRPD.

Interacts with METTL3.

Interacts with DDX3X (By similarity).

UniRule annotationBy similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
252584, 2 interactors

Protein interaction database and analysis system

More...
IntActi
Q4G061, 7 interactors

Molecular INTeraction database

More...
MINTi
Q4G061

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000057188

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini168 – 251RRMUniRule annotationAdd BLAST84
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati315 – 353WD 1Add BLAST39
Repeati355 – 400WD 2Add BLAST46
Repeati404 – 442WD 3Add BLAST39
Repeati543 – 584WD 4Add BLAST42
Repeati632 – 677WD 5Add BLAST46

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni107 – 396Sufficient for interaction with EIF3EUniRule annotationAdd BLAST290
Regioni153 – 257Sufficient for interaction with EIF3JUniRule annotationAdd BLAST105

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The RRM domain mediates interaction with EIF3J.UniRule annotation

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the eIF-3 subunit B family.UniRule annotation

Keywords - Domaini

Repeat, WD repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2314, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00550000074913

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_011152_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q4G061

Identification of Orthologs from Complete Genome Data

More...
OMAi
LIDFSPN

Database of Orthologous Groups

More...
OrthoDBi
1194797at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12278, RRM_eIF3B, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 2 hits
3.30.70.330, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_03001, eIF3b, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011400, EIF3B
IPR034363, eIF3B_RRM
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
IPR013979, TIF_beta_prop-like
IPR015943, WD40/YVTN_repeat-like_dom_sf

The PANTHER Classification System

More...
PANTHERi
PTHR14068, PTHR14068, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08662, eIF2A, 1 hit
PF00076, RRM_1, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF036424, eIF3b, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360, RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928, SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102, RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4G061-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQDAENVAAP EAAEERAEPA RQQPVSESPP TDEAAGSGGS EVGRTEDAEE
60 70 80 90 100
DAEARPEPEV RAKPAAQSEE ETAASPAASP TPQSAQEPSA PGKAEAGGEQ
110 120 130 140 150
ARHPSARAEE EGGSDGSAAE AEPRALENGE ADEPSFSDPE DFVDDVSEEE
160 170 180 190 200
LLGDVLKDRP QEADGIDSVI VVDNVPQVGP DRLEKLKNVI HKIFSKFGKI
210 220 230 240 250
INDYYPEEDG KTKGYIFLEY ASPAHAVDAV KNADGYKLDK QHTFRVNLFT
260 270 280 290 300
DFDKYMTISD EWDIPEKQPF KDLGNLRYWL EEAECRDQYS VIFESGDRTS
310 320 330 340 350
IFWNDVKDPV SIEERARWTE TYVRWSPKGT YLATFHQRGI ALWGGDKFKQ
360 370 380 390 400
IQRFSHQGVQ LIDFSPCERY LVTFSPLMDT QDDPQAIIIW DILTGHKKRG
410 420 430 440 450
FHCESSAHWP IFKWSHDGKF FARMTLDTLS IYETPSMGLL DKKSLKISGI
460 470 480 490 500
KDFSWSPGGN IIAFWVPEDK DIPARVTLMQ LPTRQEIRVR NLFNVVDCKL
510 520 530 540 550
HWQKNGDYLC VKVDRTPKGT QGVVTNFEIF RMREKQVPVD VVEMKETIIA
560 570 580 590 600
FAWEPNGSKF AVLHGEAPRI SVSFYHVKSN GKIELIKMFD KQQANTIFWS
610 620 630 640 650
PQGQFVVLAG LRSMNGALAF VDTSDCTVMN IAEHYMASDV EWDPTGRYVV
660 670 680 690 700
TSVSWWSHKV DNAYWLWTFQ GRLLQKNNKD RFCQLLWRPR PPTLLSQDQI
710 720 730 740 750
KQIKKDLKKY SKIFEQKDRL SQSKASKELV ERRRTMMEDF RQYRKMAQEL
760 770 780 790
YMKQKNERLE LRGGVDTDEL DSNVDDWEEE TIEFFVTEEV IPLGSQE
Length:797
Mass (Da):90,911
Last modified:August 30, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDACAA7CABE41EBA2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC098728 mRNA Translation: AAH98728.1

NCBI Reference Sequences

More...
RefSeqi
NP_001026810.1, NM_001031640.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000060444; ENSRNOP00000057188; ENSRNOG00000001253

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
288516

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:288516

UCSC genome browser

More...
UCSCi
RGD:1309018, rat

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC098728 mRNA Translation: AAH98728.1
RefSeqiNP_001026810.1, NM_001031640.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi252584, 2 interactors
IntActiQ4G061, 7 interactors
MINTiQ4G061
STRINGi10116.ENSRNOP00000057188

PTM databases

iPTMnetiQ4G061
PhosphoSitePlusiQ4G061

Proteomic databases

jPOSTiQ4G061
PaxDbiQ4G061
PRIDEiQ4G061

Genome annotation databases

EnsembliENSRNOT00000060444; ENSRNOP00000057188; ENSRNOG00000001253
GeneIDi288516
KEGGirno:288516
UCSCiRGD:1309018, rat

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
8662
RGDi1309018, Eif3b

Phylogenomic databases

eggNOGiKOG2314, Eukaryota
GeneTreeiENSGT00550000074913
HOGENOMiCLU_011152_1_0_1
InParanoidiQ4G061
OMAiLIDFSPN
OrthoDBi1194797at2759

Enzyme and pathway databases

ReactomeiR-RNO-156827, L13a-mediated translational silencing of Ceruloplasmin expression
R-RNO-72649, Translation initiation complex formation
R-RNO-72689, Formation of a pool of free 40S subunits
R-RNO-72695, Formation of the ternary complex, and subsequently, the 43S complex
R-RNO-72702, Ribosomal scanning and start codon recognition
R-RNO-72706, GTP hydrolysis and joining of the 60S ribosomal subunit

Miscellaneous databases

Protein Ontology

More...
PROi
PR:Q4G061

Gene expression databases

BgeeiENSRNOG00000001253, Expressed in testis and 21 other tissues
GenevisibleiQ4G061, RN

Family and domain databases

CDDicd12278, RRM_eIF3B, 1 hit
Gene3Di2.130.10.10, 2 hits
3.30.70.330, 1 hit
HAMAPiMF_03001, eIF3b, 1 hit
InterProiView protein in InterPro
IPR011400, EIF3B
IPR034363, eIF3B_RRM
IPR012677, Nucleotide-bd_a/b_plait_sf
IPR035979, RBD_domain_sf
IPR000504, RRM_dom
IPR013979, TIF_beta_prop-like
IPR015943, WD40/YVTN_repeat-like_dom_sf
PANTHERiPTHR14068, PTHR14068, 1 hit
PfamiView protein in Pfam
PF08662, eIF2A, 1 hit
PF00076, RRM_1, 1 hit
PIRSFiPIRSF036424, eIF3b, 1 hit
SMARTiView protein in SMART
SM00360, RRM, 1 hit
SUPFAMiSSF54928, SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102, RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiEIF3B_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4G061
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: August 30, 2005
Last modified: April 7, 2021
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families
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