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Entry version 140 (10 Feb 2021)
Sequence version 1 (30 Aug 2005)
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Protein

Chaperone protein ClpB

Gene

clpB

Organism
Psychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.UniRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChaperoneUniRule annotationARBA annotation
Biological processStress responseUniRule annotation
LigandATP-bindingUniRule annotationARBA annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
PARC259536:PSYC_RS04290-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chaperone protein ClpBUniRule annotationARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:clpBUniRule annotationImported
Ordered Locus Names:Psyc_0823Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPsychrobacter arcticus (strain DSM 17307 / VKM B-2377 / 273-4)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri259536 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesMoraxellaceaePsychrobacter
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000546 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homohexamer; The oligomerization is ATP-dependent.

UniRule annotation

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
259536.Psyc_0823

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini3 – 143Clp RInterPro annotationAdd BLAST141

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili409 – 465UniRule annotationAdd BLAST57

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ClpA/ClpB family.UniRule annotationARBA annotation

Keywords - Domaini

Coiled coilUniRule annotationARBA annotation, RepeatPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
COG0542, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005070_4_0_6

Identification of Orthologs from Complete Genome Data

More...
OMAi
SKMMQGE

Database of Orthologous Groups

More...
OrthoDBi
44062at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1780.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003593, AAA+_ATPase
IPR003959, ATPase_AAA_core
IPR017730, Chaperonin_ClpB
IPR019489, Clp_ATPase_C
IPR036628, Clp_N_dom_sf
IPR004176, Clp_R_dom
IPR001270, ClpA/B
IPR018368, ClpA/B_CS1
IPR028299, ClpA/B_CS2
IPR041546, ClpA/ClpB_AAA_lid
IPR027417, P-loop_NTPase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00004, AAA, 1 hit
PF07724, AAA_2, 1 hit
PF17871, AAA_lid_9, 1 hit
PF02861, Clp_N, 2 hits
PF10431, ClpB_D2-small, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00300, CLPPROTEASEA

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00382, AAA, 2 hits
SM01086, ClpB_D2-small, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits
SSF81923, SSF81923, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR03346, chaperone_ClpB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51903, CLP_R, 1 hit
PS00870, CLPAB_1, 1 hit
PS00871, CLPAB_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q4FTI2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRFEKFTQKL QSAIQEAQSL ALGRDHTGID PVHLLAVLLQ DESNLSICQQ
60 70 80 90 100
AGASIPALKN GVAKALDNQA TISEPTGDVN LNPNSVKILN LADRQAQKEG
110 120 130 140 150
DDFIATEWVM LALAEQGDTK KIFESAGVTA NKLKAVIEQL RGDDTVNNQN
160 170 180 190 200
AEDQRDALNK YTINLTEQAE LGKLDPVIGR DEEIRRTIQV LSRRTKNNPV
210 220 230 240 250
LIGEPGVGKT AIVEGLAQKI INGDVPEGLR RKEVLSLDLG ALIAGAKFRG
260 270 280 290 300
EFEERLKAVL SDLSKQEGNV ILFIDELHTL VGAGKADGAM DAGNMLKPAL
310 320 330 340 350
ARGELHCVGA TTLDEYRKYI EKDAALERRF QKVLVDEPTV EDTIAILRGL
360 370 380 390 400
KERYELHHGV DIQDSAIIAA ARMSHRYITD RKLPDKAIDL IDEAASRLRM
410 420 430 440 450
EMDSKPESLG KLDSRLIQLK MQREVLKNEE DAGAQAERKV LDAQIEELEK
460 470 480 490 500
EYADLNEIWQ AEKALVKGSQ QLKDELDKAR IAYDKASREG DYETMSKLQY
510 520 530 540 550
ETIPQLERRI HESDLAEQKE QTGENSGVKL LRNKVTDNEI AEVVAAATGI
560 570 580 590 600
PVSKMLQGER DKMLAMEENL HERVIGQDEA VEAVANAVRR SRAGLSDPNR
610 620 630 640 650
PSGSFLFLGP TGVGKTELTK SLANFLFDSE DAIVRIDMSE YMEKHSVSRL
660 670 680 690 700
VGAPPGYVGY EEGGALTEAV RRKPYSVILF DEVEKAHPDV FNILLQVLDD
710 720 730 740 750
GRLTDSQGRV VDFKNTVIIM TSNLGSHKIQ EMVGESYEDI KAEVMDSVGQ
760 770 780 790 800
HFRPEFVNRI DEIVVFHPLG MSQMAGIAAI QLNRLRQRLY ERELDIELSA
810 820 830 840 850
DAMNKLVAVG YDPVYGARPL KRAIQQEIEN PLSLKLLAGD FVAGDIIKVD
860
VGADDKLTFD KLRMS
Length:865
Mass (Da):95,908
Last modified:August 30, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFAAC3AEFC6042A2B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP000082 Genomic DNA Translation: AAZ18676.1

NCBI Reference Sequences

More...
RefSeqi
WP_011280103.1, NC_007204.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAZ18676; AAZ18676; Psyc_0823

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
par:Psyc_0823

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000082 Genomic DNA Translation: AAZ18676.1
RefSeqiWP_011280103.1, NC_007204.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi259536.Psyc_0823

Genome annotation databases

EnsemblBacteriaiAAZ18676; AAZ18676; Psyc_0823
KEGGipar:Psyc_0823

Phylogenomic databases

eggNOGiCOG0542, Bacteria
HOGENOMiCLU_005070_4_0_6
OMAiSKMMQGE
OrthoDBi44062at2

Enzyme and pathway databases

BioCyciPARC259536:PSYC_RS04290-MONOMER

Family and domain databases

Gene3Di1.10.1780.10, 1 hit
InterProiView protein in InterPro
IPR003593, AAA+_ATPase
IPR003959, ATPase_AAA_core
IPR017730, Chaperonin_ClpB
IPR019489, Clp_ATPase_C
IPR036628, Clp_N_dom_sf
IPR004176, Clp_R_dom
IPR001270, ClpA/B
IPR018368, ClpA/B_CS1
IPR028299, ClpA/B_CS2
IPR041546, ClpA/ClpB_AAA_lid
IPR027417, P-loop_NTPase
PfamiView protein in Pfam
PF00004, AAA, 1 hit
PF07724, AAA_2, 1 hit
PF17871, AAA_lid_9, 1 hit
PF02861, Clp_N, 2 hits
PF10431, ClpB_D2-small, 1 hit
PRINTSiPR00300, CLPPROTEASEA
SMARTiView protein in SMART
SM00382, AAA, 2 hits
SM01086, ClpB_D2-small, 1 hit
SUPFAMiSSF52540, SSF52540, 2 hits
SSF81923, SSF81923, 1 hit
TIGRFAMsiTIGR03346, chaperone_ClpB, 1 hit
PROSITEiView protein in PROSITE
PS51903, CLP_R, 1 hit
PS00870, CLPAB_1, 1 hit
PS00871, CLPAB_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4FTI2_PSYA2
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4FTI2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 30, 2005
Last sequence update: August 30, 2005
Last modified: February 10, 2021
This is version 140 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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