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UniProtKB - Q4DK87 (Q4DK87_TRYCC)

Entry version 43 (19 Jan 2022)
Sequence version 1 (13 Sep 2005)
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Protein

Chorein N-terminal domain-containing protein

Gene

Tc00.1047053509611.189

Organism
Trypanosoma cruzi (strain CL Brener)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Chorein N-terminal domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:Tc00.1047053509611.189Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiTrypanosoma cruzi (strain CL Brener)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri353153 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Trypanosoma › Schizotrypanum ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002296 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q4DK87

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 85Chorein N-terminalInterPro annotationAdd BLAST69

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni122 – 146DisorderedSequence analysisAdd BLAST25

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG502R4MM, Eukaryota

Database of Orthologous Groups

More...OrthoDBi		12773at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR026854, VPS13-like_N

Pfam protein domain database

More...Pfami		View protein in Pfam
PF12624, Chorein_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

Q4DK87-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLQQAVSYVI SSLAKIGDIN ACNVESSLRE RTLRIRDMSL RQDTLNTFLP 
        60         70         80         90        100
FTIQCGKVGD LRVKIPWPAS NEPLLLCCEG MAFTLNGETS QSCTKEMTRE 
       110        120        130        140        150
EIRGGITEES ILGTVVTSSV PVNSHEEQRS AAPLASEENS EERETSWSAA 
       160        170        180        190        200
LEDDDYMSCQ SVSNTSFASC DSQEDLASLP QNGKGFFSFL VNAASRSVSW 
       210        220        230        240        250
VMNRPIHVQL KNPCVVWPCD SHSDVGFEIT VSEIMVKIEP TLEAGAELMK 
       260        270        280        290        300
VIVITFSGVA VCANAAKEQT QKIVEIDHLS IRITSVYSSA GILCRKNVAI 
       310        320        330        340        350
VFDGVSSLFF DEDALRSLTR CAVSHGIMKE VPEYCRPFYK LRSLSSRWSY 
       360        370        380        390        400
AKSCVFAFIR DRRRRYNFNS SHLHFYAEAR TSYLALLDYC HRTRDIAEKR 
       410        420        430        440        450
EQLADIEGDI RYRDVVLFLR RKVQERYSTT VLAGSTGAGV TPPPTQPSDA 
       460        470        480        490        500
RQFVVVSSLH VDAKITCVRL PAETTVWLRD VAFVKRRGES NFSVGNVTLV 
       510        520        530        540        550
AGGKSQLLRA PDSGEPFFSL QQTESNGMTF VRTTLEALRF ITTSNWMLQL 
       560        570        580        590        600
VQPIMVAMPH VLRAIPETNC NAPETKLSNR CEKTTSFVFP LIDFHVDDLR 
       610        620        630        640        650
FHLKQLSLTH IERTSGDSRV GLLMKELSVR FGEETDVLSP MKVEMTEEED 
       660        670        680        690        700
ILVSAVTLNV SNALWEYLYH VRTEWNDALL RVSNMPGFVS RVQSTTGKTQ 
       710        720        730        740        750
IKKSFAEVCC EAELKEEFNS ALKLQRTYLL GVVITFEPLN LSMQLGTMNM 
       760        770        780        790        800
WRGAQTCGFP SVHANISSFE FSTDHVEGGV LTVTCPSGIL YSKTSSTSDA 
       810        820        830        840        850
SRVNVSIGVL ESVWKASSTR NLLHIDAMQF HVYGDATYCS AETLRFLDAL 
       860        870        880        890        900
TFAPIKCFYC RQLSSIPTTA RPYLASSLQV SVCLAEVCMQ RLIFLELDLL 
       910        920        930        940        950
GTLIKDYATF FVNNLVPTEA YRLFFSGFSN LAFVMYASSC AVKFGGDEAL 
       960        970        980        990       1000
MCRVNMPSIN GGAGAPLVNF GELLPELREA SPLTLINVCE KLLADISMPH 
      1010       1020       1030       1040       1050
LEVEVFHHRF MSIGLCATVS SFTATLPIAV EDFWDDAVHA VKRSPAECTA 
      1060       1070       1080       1090       1100
PSIKLNVGDM IRLEVEGVKY AQQSAPFPEE LSGVFSDCDM DSDTSVVACE 
      1110       1120       1130       1140       1150
KYTHAVVKNW NVHLKGVSEA DAVKELLGLW MELRHMMNSI QRRNVVNCTL 
      1160       1170       1180       1190       1200
LRGGHYNLDR TGPWFFDSPG EMVLVEDCTF LSCTSGMHMV VCSGTHVCFR 
      1210       1220       1230       1240       1250
RCHFSSFFQH AITVEDECAS FVCDNCIGED FGGESNATGA QAEVEKKTVQ 
      1260       1270       1280       1290       1300
KFLFSFHRGA VCLTLRDECR LTLNLSTVDL RFFTCFKKTV SHLRLQRGRL 
      1310       1320       1330       1340       1350
EFMEKGALHG LVSRMDLDLD WTLRHRDDYA TLSSSLRVES VSIPVLLFGT 
      1360       1370       1380       1390       1400
MRCLRGVWNA EVPFSEASVR EYPSPVKTRG FSVARWKALV TVSIIPVELC 
      1410       1420       1430       1440       1450
PPSGGAPLIS FILDSTSVVS RRETTGEAFL EARSGIQQLS LWEFSSQSHV 
      1460       1470       1480       1490       1500
SLLRNLLSVL VVARTEDFSS ASCDVSVSPC ELSLSSEQIK CVLSLLTFMQ 
      1510       1520       1530
GCDDAETVPY AVRLENYLGV EVTLQDAADQ
Length:1,530
Mass (Da):170,190
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9498D0570E4B14CF
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1530Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AAHK01000392 Genomic DNA Translation: EAN92957.1

NCBI Reference Sequences

More...RefSeqi		XP_814808.1, XM_809715.1

Genome annotation databases

Ensembl protists genome annotation project

More...EnsemblProtistsi		EAN92957; EAN92957; Tc00.1047053509611.189

Database of genes from NCBI RefSeq genomes

More...GeneIDi		3546395

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		tcr:509611.189

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AAHK01000392 Genomic DNA Translation: EAN92957.1
RefSeqiXP_814808.1, XM_809715.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Proteomic databases

PaxDbiQ4DK87

Genome annotation databases

EnsemblProtistsiEAN92957; EAN92957; Tc00.1047053509611.189
GeneIDi3546395
KEGGitcr:509611.189

Phylogenomic databases

eggNOGiENOG502R4MM, Eukaryota
OrthoDBi12773at2759

Family and domain databases

InterProiView protein in InterPro
IPR026854, VPS13-like_N
PfamiView protein in Pfam
PF12624, Chorein_N, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ4DK87_TRYCC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4DK87
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 13, 2005
Last sequence update: September 13, 2005
Last modified: January 19, 2022
This is version 43 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
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