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Entry version 84 (26 Feb 2020)
Sequence version 1 (13 Sep 2005)
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Protein

Deleted in malignant brain tumors 1 protein

Gene

DMBT1

Organism
Sus scrofa (Pig)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract. Required for terminal differentiation of columnar epithelial cells during early embryogenesis. Displays a broad calcium-dependent binding spectrum against both Gram-positive and Gram-negative bacteria, suggesting a role in defense against bacterial pathogens. Binds to a range of poly-sulfated and poly-phosphorylated ligands which may explain its broad bacterial-binding specificity. Inhibits cytoinvasion of S.enterica. Associates with the actin cytoskeleton and is involved in its remodeling during regulated exocytosis. Interacts with pancreatic zymogens in a pH-dependent manner and may act as a Golgi cargo receptor in the regulated secretory pathway of the pancreatic acinar cell (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Deleted in malignant brain tumors 1 protein
Alternative name(s):
Hensin
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:DMBT1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSus scrofa (Pig)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9823 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaSuinaSuidaeSus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008227 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1168 – 1188HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cytoplasmic vesicle, Membrane, Secreted

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 19Sequence analysisAdd BLAST19
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000004539020 – 1204Deleted in malignant brain tumors 1 proteinAdd BLAST1185

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi109 ↔ 173By similarity
Disulfide bondi122 ↔ 183By similarity
Disulfide bondi153 ↔ 163By similarity
Disulfide bondi257 ↔ 321By similarity
Disulfide bondi270 ↔ 331By similarity
Disulfide bondi301 ↔ 311By similarity
Disulfide bondi405 ↔ 469By similarity
Disulfide bondi418 ↔ 479By similarity
Disulfide bondi449 ↔ 459By similarity
Disulfide bondi517 ↔ 543By similarity
Disulfide bondi570 ↔ 592By similarity
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi585N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi593N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi640N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi662 ↔ 726By similarity
Disulfide bondi675 ↔ 736By similarity
Disulfide bondi706 ↔ 716By similarity
Glycosylationi749N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi752 ↔ 778By similarity
Disulfide bondi803 ↔ 825By similarity
Glycosylationi932N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi977N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi993N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1029N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1039 ↔ 1097By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Highly N- and O-glycosylated. The O-glycans are heavily sulfated (By similarity).By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q4A3R3

PeptideAtlas

More...
PeptideAtlasi
Q4A3R3

PRoteomics IDEntifications database

More...
PRIDEi
Q4A3R3

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with LGALS3. Binds SFTPD and SPAR in a calcium-dependent manner (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
9823.ENSSSCP00000003229

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q4A3R3

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini84 – 184SRCR 1PROSITE-ProRule annotationAdd BLAST101
Domaini232 – 332SRCR 2PROSITE-ProRule annotationAdd BLAST101
Domaini380 – 480SRCR 3PROSITE-ProRule annotationAdd BLAST101
Domaini517 – 628CUB 1PROSITE-ProRule annotationAdd BLAST112
Domaini634 – 737SRCR 4PROSITE-ProRule annotationAdd BLAST104
Domaini752 – 861CUB 2PROSITE-ProRule annotationAdd BLAST110
Domaini870 – 1118ZPPROSITE-ProRule annotationAdd BLAST249

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi219 – 222Poly-Thr4
Compositional biasi367 – 370Poly-Thr4
Compositional biasi506 – 509Poly-Thr4

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The SRCR domains mediate binding to bacteria.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the DMBT1 family.Curated

Keywords - Domaini

Repeat, Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q4A3R3

KEGG Orthology (KO)

More...
KOi
K13912

Database of Orthologous Groups

More...
OrthoDBi
1095487at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00041 CUB, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.290, 2 hits
3.10.250.10, 4 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000859 CUB_dom
IPR035914 Sperma_CUB_dom_sf
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
IPR001507 ZP_dom
IPR017977 ZP_dom_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00431 CUB, 2 hits
PF00530 SRCR, 4 hits
PF00100 Zona_pellucida, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00258 SPERACTRCPTR

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00042 CUB, 2 hits
SM00202 SR, 4 hits
SM00241 ZP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49854 SSF49854, 2 hits
SSF56487 SSF56487, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01180 CUB, 2 hits
PS00420 SRCR_1, 3 hits
PS50287 SRCR_2, 4 hits
PS00682 ZP_1, 1 hit
PS51034 ZP_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q4A3R3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGTSAVILEI CLLLSQVLTT VSSTTQTEST TEDRTQITET AFWETQTINS
60 70 80 90 100
VSESDLPGTH ASSFHTEEPL TTIAAEGTEW DLALRLVNGG DRCQGRVEIL
110 120 130 140 150
YQGSWGTVCD DSWDTNDANV VCRQLGCGWA VSAPGSARFG QGLGPILLDD
160 170 180 190 200
LRCSGHETYL WSCPHSGWKT HNCGHQEDAG VICSGAQRSS TVIPDWWYTT
210 220 230 240 250
TRSQTAHIRS TIPAWWHPTT TTAARTEWDL ALRLVNGGDR CQGRVEVLYQ
260 270 280 290 300
GSWGTVCDDS WDTNDANVVC RQLGCGWAVS APGSARFGQG SGPILLDDLR
310 320 330 340 350
CSGHETYLWS CPHSGWNTHN CGHHEDAGVI CSDAQRSSTV IPDWWYTTTP
360 370 380 390 400
SQTAHIRSTI PAWWHPTTTT AARTEWDLAL RLVNGGDRCQ GRVEVLYQGS
410 420 430 440 450
WGTVCDDSWD TNDANVVCRQ LGCGWAVSAP GSARFGQGSG PILLDDLRCS
460 470 480 490 500
GHETYLWSCP HSGWNTHNCG HHEDAGVICS DAQRSSTVIP DWWYTTTPSQ
510 520 530 540 550
TWWHPTTTTA ASPSSPCGGF LTSASGTFSS PSYPGLYPNN ANCVWEIEVN
560 570 580 590 600
SGYRINLGFN NLQLEVHINC IYDYIEIFDE SPGSNTSLGK ICNHTSQIFT
610 620 630 640 650
SSYNRMTVRF RSDGSVQKPG FSAWYNSFPR DASLRLVNSN SSYPSCAGRV
660 670 680 690 700
EIYQGGRWGT VCDDGWDIQD AQVVCRQLGC GNAVSAPGNA YFGPGSGPIT
710 720 730 740 750
LDDVACSGTE STLWQCRNRG WFSHNCGHSE DAGVICSVPA FTTTPPATNY
760 770 780 790 800
SCGGFLSQAA GGFNSPFYPG NYPNNANCVW DIEVQNNYRV TVVFRDVQLE
810 820 830 840 850
SGCNFDYIEV FDGPYRSSPL LARVCNGASG SFTSSSNFMS IRFISDVSVT
860 870 880 890 900
RAGFRANYYS SPSSGSTRLH CLQNHMQASV STSYLQSLGY SARDLVIPGW
910 920 930 940 950
EWSYQCQPQI TSTQVTFTIP YSSCGTIQRV DNDTITYSNS LRAAVSSGII
960 970 980 990 1000
KRKKDLNMYV SCRMLQNTWV NTVYIANDTL EVQNVQYGNF DVNISFFTSS
1010 1020 1030 1040 1050
SFLYPVRSSP YYVDLNQNLY LQAELLHANA SLALFVDTCV ASPYPNDFTT
1060 1070 1080 1090 1100
LTYDLIRSGC VKDETYQSYS QPSPRIVRFK FSSFHFLSRF PSVYLQCKMV
1110 1120 1130 1140 1150
VCRAFDSSSR CRRGCVVRSK RDVGSYQEKV DVVLGPIQLQ TLHAEKRSLD
1160 1170 1180 1190 1200
QPAVDLEEKA SAQGSYDGAA ISAGIFLVVV LAVAAFTLGR RGRAADGQPL

ISKT
Length:1,204
Mass (Da):132,225
Last modified:September 13, 2005 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i939E8B7F4825B976
GO
Isoform 2 (identifier: Q4A3R3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     78-78: T → TEWDLALRLV...PLTTIAAEGT

Show »
Length:1,349
Mass (Da):147,857
Checksum:i695ADD2D226E1815
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti445D → G in CAB03556 (Ref. 3) Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03465778T → TEWDLALRLVNGGDRCQGRV EILYQGSWGTVCDDSWDTND ANVVCRQLGCGWAISAPGSA RFGQGSGPILLDDLRCSGHE TYLWSCPHSGWKTHNCGHQE DAGVICSGAQRSSTVIPAWW HPTTTTTATSSFHTEEPLTT IAAEGT in isoform 2. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ853849 Genomic DNA Translation: CAJ27171.1
AM048631 mRNA Translation: CAJ14977.1
Z81180 mRNA Translation: CAB03556.1

NCBI Reference Sequences

More...
RefSeqi
NP_001041653.1, NM_001048188.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
751862

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ssc:751862

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ853849 Genomic DNA Translation: CAJ27171.1
AM048631 mRNA Translation: CAJ14977.1
Z81180 mRNA Translation: CAB03556.1
RefSeqiNP_001041653.1, NM_001048188.1

3D structure databases

SMRiQ4A3R3
ModBaseiSearch...

Protein-protein interaction databases

STRINGi9823.ENSSSCP00000003229

Proteomic databases

PaxDbiQ4A3R3
PeptideAtlasiQ4A3R3
PRIDEiQ4A3R3

Genome annotation databases

GeneIDi751862
KEGGissc:751862

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
1755

Phylogenomic databases

InParanoidiQ4A3R3
KOiK13912
OrthoDBi1095487at2759

Family and domain databases

CDDicd00041 CUB, 2 hits
Gene3Di2.60.120.290, 2 hits
3.10.250.10, 4 hits
InterProiView protein in InterPro
IPR000859 CUB_dom
IPR035914 Sperma_CUB_dom_sf
IPR001190 SRCR
IPR017448 SRCR-like_dom
IPR036772 SRCR-like_dom_sf
IPR001507 ZP_dom
IPR017977 ZP_dom_CS
PfamiView protein in Pfam
PF00431 CUB, 2 hits
PF00530 SRCR, 4 hits
PF00100 Zona_pellucida, 1 hit
PRINTSiPR00258 SPERACTRCPTR
SMARTiView protein in SMART
SM00042 CUB, 2 hits
SM00202 SR, 4 hits
SM00241 ZP, 1 hit
SUPFAMiSSF49854 SSF49854, 2 hits
SSF56487 SSF56487, 4 hits
PROSITEiView protein in PROSITE
PS01180 CUB, 2 hits
PS00420 SRCR_1, 3 hits
PS50287 SRCR_2, 4 hits
PS00682 ZP_1, 1 hit
PS51034 ZP_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiDMBT1_PIG
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q4A3R3
Secondary accession number(s): Q0W9P8, Q95316
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: September 13, 2005
Last modified: February 26, 2020
This is version 84 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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