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Entry version 112 (12 Aug 2020)
Sequence version 3 (17 Oct 2006)
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Protein

Microtubule-associated protein 9

Gene

MAP9

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • microtubule binding Source: UniProtKB

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell division, Mitosis

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...
PathwayCommonsi
Q49MG5

SIGNOR Signaling Network Open Resource

More...
SIGNORi
Q49MG5

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Microtubule-associated protein 9
Alternative name(s):
Aster-associated protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAP9
Synonyms:ASAP
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 4

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000164114.18

Human Gene Nomenclature Database

More...
HGNCi
HGNC:26118, MAP9

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
610070, gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q49MG5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
79884

Open Targets

More...
OpenTargetsi
ENSG00000164114

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA145148442

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q49MG5, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
MAP9

Domain mapping of disease mutations (DMDM)

More...
DMDMi
116242626

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002477532 – 647Microtubule-associated protein 9Add BLAST646

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineCombined sources1
Modified residuei12PhosphotyrosineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q49MG5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q49MG5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q49MG5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q49MG5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q49MG5

PeptideAtlas

More...
PeptideAtlasi
Q49MG5

PRoteomics IDEntifications database

More...
PRIDEi
Q49MG5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
62073 [Q49MG5-1]
62074 [Q49MG5-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q49MG5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q49MG5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Constitutively expressed during the cell cycle.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000164114, Expressed in primary visual cortex and 222 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q49MG5, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q49MG5, HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
ENSG00000164114, Tissue enhanced (brain, parathyroid gland)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Binds to purified microtubules via its C-terminus.

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
122969, 8 interactors

Protein interaction database and analysis system

More...
IntActi
Q49MG5, 7 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000310593

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q49MG5, protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili184 – 210Sequence analysisAdd BLAST27
Coiled coili298 – 328Sequence analysisAdd BLAST31
Coiled coili443 – 628Sequence analysisAdd BLAST186

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG502R2PC, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111184

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q49MG5

KEGG Orthology (KO)

More...
KOi
K10434

Identification of Orthologs from Complete Genome Data

More...
OMAi
AFSNWCE

Database of Orthologous Groups

More...
OrthoDBi
1024159at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q49MG5

TreeFam database of animal gene trees

More...
TreeFami
TF328794

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026106, MAP9

The PANTHER Classification System

More...
PANTHERi
PTHR14739, PTHR14739, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 6 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q49MG5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSDEVFSTTL AYTKSPKVTK RTTFQDELIR AITARSARQR SSEYSDDFDS
60 70 80 90 100
DEIVSLGDFS DTSADENSVN KKMNDFHISD DEEKNPSKLL FLKTNKSNGN
110 120 130 140 150
ITKDEPVCAI KNEEEMAPDG CEDIVVKSFS ESQNKDEEFE KDKIKMKPKP
160 170 180 190 200
RILSIKSTSS AENNSLDTDD HFKPSPRPRS MLKKKSHMEE KDGLEDKETA
210 220 230 240 250
LSEELELHSA PSSLPTPNGI QLEAEKKAFS ENLDPEDSCL TSLASSSLKQ
260 270 280 290 300
ILGDSFSPGS EGNASGKDPN EEITENHNSL KSDENKENSF SADHVTTAVE
310 320 330 340 350
KSKESQVTAD DLEEEKAKAE LIMDDDRTVD PLLSKSQSIL ISTSATASSK
360 370 380 390 400
KTIEDRNIKN KKSTNNRASS ASARLMTSEF LKKSSSKRRT PSTTTSSHYL
410 420 430 440 450
GTLKVLDQKP SQKQSIEPDR ADNIRAAVYQ EWLEKKNVYL HEMHRIKRIE
460 470 480 490 500
SENLRIQNEQ KKAAKREEAL ASFEAWKAMK EKEAKKIAAK KRLEEKNKKK
510 520 530 540 550
TEEENAARKG EALQAFEKWK EKKMEYLKEK NRKEREYERA KKQKEEETVA
560 570 580 590 600
EKKKDNLTAV EKWNEKKEAF FKQKEKEKIN EKRKEELKRA EKKDKDKQAI
610 620 630 640
NEYEKWLENK EKQERIERKQ KKRHSFLESE ALPPWSPPSR TVFAKVF
Length:647
Mass (Da):74,234
Last modified:October 17, 2006 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1F0BDE2986845B39
GO
Isoform 2 (identifier: Q49MG5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     374-377: RLMT → ARSG
     378-647: Missing.

Show »
Length:377
Mass (Da):41,582
Checksum:iB76E5EBED1224B79
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
E7ETZ8E7ETZ8_HUMAN
Microtubule-associated protein 9
MAP9
623Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A2VCS9A2VCS9_HUMAN
MAP9 protein
MAP9
488Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0C4DG83A0A0C4DG83_HUMAN
Aster-associated protein, isoform C...
MAP9 ASAP, hCG_26928
376Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A8MSM7A8MSM7_HUMAN
Microtubule-associated protein 9
MAP9
190Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0Y945H0Y945_HUMAN
Microtubule-associated protein 9
MAP9
33Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
C9JXH8C9JXH8_HUMAN
Microtubule-associated protein 9
MAP9
31Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti116M → L in BAB14978 (PubMed:14702039).Curated1
Sequence conflicti450E → G in BAB14978 (PubMed:14702039).Curated1
Sequence conflicti575E → K in AAW02921 (PubMed:16049101).Curated1
Sequence conflicti631A → T in CAH18129 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051152146M → V. Corresponds to variant dbSNP:rs34082815Ensembl.1
Natural variantiVAR_027151177R → W2 PublicationsCorresponds to variant dbSNP:rs3733391Ensembl.1
Natural variantiVAR_051153499K → R. Corresponds to variant dbSNP:rs1058992Ensembl.1
Natural variantiVAR_051154601N → D1 PublicationCorresponds to variant dbSNP:rs2305050Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_020037374 – 377RLMT → ARSG in isoform 2. 1 Publication4
Alternative sequenceiVSP_020038378 – 647Missing in isoform 2. 1 PublicationAdd BLAST270

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY690636 mRNA Translation: AAW02921.1
AK024730 mRNA Translation: BAB14978.1 Sequence problems.
AK024812 mRNA Translation: BAB15017.1
AC097467 Genomic DNA Translation: AAY40981.1
CR749274 mRNA Translation: CAH18129.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS35493.1 [Q49MG5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001034669.1, NM_001039580.1 [Q49MG5-1]
XP_011530555.1, XM_011532253.1 [Q49MG5-1]
XP_011530556.1, XM_011532254.2 [Q49MG5-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000311277; ENSP00000310593; ENSG00000164114 [Q49MG5-1]
ENST00000650955; ENSP00000498412; ENSG00000164114 [Q49MG5-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
79884

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:79884

UCSC genome browser

More...
UCSCi
uc003ios.4, human [Q49MG5-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY690636 mRNA Translation: AAW02921.1
AK024730 mRNA Translation: BAB14978.1 Sequence problems.
AK024812 mRNA Translation: BAB15017.1
AC097467 Genomic DNA Translation: AAY40981.1
CR749274 mRNA Translation: CAH18129.1
CCDSiCCDS35493.1 [Q49MG5-1]
RefSeqiNP_001034669.1, NM_001039580.1 [Q49MG5-1]
XP_011530555.1, XM_011532253.1 [Q49MG5-1]
XP_011530556.1, XM_011532254.2 [Q49MG5-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi122969, 8 interactors
IntActiQ49MG5, 7 interactors
STRINGi9606.ENSP00000310593

PTM databases

iPTMnetiQ49MG5
PhosphoSitePlusiQ49MG5

Polymorphism and mutation databases

BioMutaiMAP9
DMDMi116242626

Proteomic databases

EPDiQ49MG5
jPOSTiQ49MG5
MassIVEiQ49MG5
MaxQBiQ49MG5
PaxDbiQ49MG5
PeptideAtlasiQ49MG5
PRIDEiQ49MG5
ProteomicsDBi62073 [Q49MG5-1]
62074 [Q49MG5-2]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
48220, 85 antibodies

Genome annotation databases

EnsembliENST00000311277; ENSP00000310593; ENSG00000164114 [Q49MG5-1]
ENST00000650955; ENSP00000498412; ENSG00000164114 [Q49MG5-1]
GeneIDi79884
KEGGihsa:79884
UCSCiuc003ios.4, human [Q49MG5-1]

Organism-specific databases

Comparative Toxicogenomics Database

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CTDi
79884
DisGeNETi79884
EuPathDBiHostDB:ENSG00000164114.18

GeneCards: human genes, protein and diseases

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GeneCardsi
MAP9
HGNCiHGNC:26118, MAP9
HPAiENSG00000164114, Tissue enhanced (brain, parathyroid gland)
MIMi610070, gene
neXtProtiNX_Q49MG5
OpenTargetsiENSG00000164114
PharmGKBiPA145148442

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG502R2PC, Eukaryota
GeneTreeiENSGT00730000111184
InParanoidiQ49MG5
KOiK10434
OMAiAFSNWCE
OrthoDBi1024159at2759
PhylomeDBiQ49MG5
TreeFamiTF328794

Enzyme and pathway databases

PathwayCommonsiQ49MG5
SIGNORiQ49MG5

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
79884, 1 hit in 875 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
MAP9, human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
79884
PharosiQ49MG5, Tbio

Protein Ontology

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PROi
PR:Q49MG5
RNActiQ49MG5, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSG00000164114, Expressed in primary visual cortex and 222 other tissues
ExpressionAtlasiQ49MG5, baseline and differential
GenevisibleiQ49MG5, HS

Family and domain databases

InterProiView protein in InterPro
IPR026106, MAP9
PANTHERiPTHR14739, PTHR14739, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAP9_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q49MG5
Secondary accession number(s): Q4W5I7
, Q68DU1, Q9H781, Q9H7B6
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 25, 2006
Last sequence update: October 17, 2006
Last modified: August 12, 2020
This is version 112 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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